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Results: 1 to 20 of 117

Cited In for PubMed (Select 19864570)

1.

Therapeutic targeting of autophagy in neurodegenerative and infectious diseases.

Rubinsztein DC, Bento CF, Deretic V.

J Exp Med. 2015 Jun 29;212(7):979-90. doi: 10.1084/jem.20150956. Epub 2015 Jun 22. Review.

PMID:
26101267
2.

Sestrin2 Protects Dopaminergic Cells against Rotenone Toxicity through AMPK-Dependent Autophagy Activation.

Hou YS, Guan JJ, Xu HD, Wu F, Sheng R, Qin ZH.

Mol Cell Biol. 2015 Aug 15;35(16):2740-51. doi: 10.1128/MCB.00285-15. Epub 2015 Jun 1.

PMID:
26031332
3.

Activation of mTOR: a culprit of Alzheimer's disease?

Cai Z, Chen G, He W, Xiao M, Yan LJ.

Neuropsychiatr Dis Treat. 2015 Apr 9;11:1015-30. doi: 10.2147/NDT.S75717. eCollection 2015. Review.

4.

Autophagy in neurodegenerative diseases: from mechanism to therapeutic approach.

Nah J, Yuan J, Jung YK.

Mol Cells. 2015 May;38(5):381-9. doi: 10.14348/molcells.2015.0034. Epub 2015 Apr 20. Review.

5.

Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy.

Mandler M, Valera E, Rockenstein E, Mante M, Weninger H, Patrick C, Adame A, Schmidhuber S, Santic R, Schneeberger A, Schmidt W, Mattner F, Masliah E.

Mol Neurodegener. 2015 Mar 19;10(1):10. [Epub ahead of print]

6.

The Interplay between Alpha-Synuclein Clearance and Spreading.

Lopes da Fonseca T, Villar-Piqué A, Outeiro TF.

Biomolecules. 2015 Apr 14;5(2):435-71. doi: 10.3390/biom5020435. Review.

7.

Genetic and chemical activation of TFEB mediates clearance of aggregated α-synuclein.

Kilpatrick K, Zeng Y, Hancock T, Segatori L.

PLoS One. 2015 Mar 19;10(3):e0120819. doi: 10.1371/journal.pone.0120819. eCollection 2015.

8.

The role of autophagy in Parkinson's disease.

Zhang L, Dong Y, Xu X, Xu Z.

Neural Regen Res. 2012 Jan 15;7(2):141-5. doi: 10.3969/j.issn.1673-5374.2012.02.011. Review.

9.

Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.

Ciechanover A, Kwon YT.

Exp Mol Med. 2015 Mar 13;47:e147. doi: 10.1038/emm.2014.117. Review.

10.

Neuronal aggregates: formation, clearance, and spreading.

Lim J, Yue Z.

Dev Cell. 2015 Feb 23;32(4):491-501. doi: 10.1016/j.devcel.2015.02.002. Review.

PMID:
25710535
11.

Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo.

Mbefo MK, Fares MB, Paleologou K, Oueslati A, Yin G, Tenreiro S, Pinto M, Outeiro T, Zweckstetter M, Masliah E, Lashuel HA.

J Biol Chem. 2015 Apr 10;290(15):9412-27. doi: 10.1074/jbc.M114.610774. Epub 2015 Feb 5.

PMID:
25657004
12.

Autophagy and neurodegeneration.

Frake RA, Ricketts T, Menzies FM, Rubinsztein DC.

J Clin Invest. 2015 Jan;125(1):65-74. doi: 10.1172/JCI73944. Epub 2015 Jan 2. Review.

PMID:
25654552
13.

HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders.

Fields J, Dumaop W, Elueteri S, Campos S, Serger E, Trejo M, Kosberg K, Adame A, Spencer B, Rockenstein E, He JJ, Masliah E.

J Neurosci. 2015 Feb 4;35(5):1921-38. doi: 10.1523/JNEUROSCI.3207-14.2015.

PMID:
25653352
14.

Spinal autophagy is differently modulated in distinct mouse models of neuropathic pain.

Berliocchi L, Maiarù M, Varano GP, Russo R, Corasaniti MT, Bagetta G, Tassorelli C.

Mol Pain. 2015 Feb 2;11(1):3. doi: 10.1186/1744-8069-11-3.

15.

Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.

Orr AG, Hsiao EC, Wang MM, Ho K, Kim DH, Wang X, Guo W, Kang J, Yu GQ, Adame A, Devidze N, Dubal DB, Masliah E, Conklin BR, Mucke L.

Nat Neurosci. 2015 Mar;18(3):423-34. doi: 10.1038/nn.3930. Epub 2015 Jan 26.

PMID:
25622143
16.

Structure of the human autophagy initiating kinase ULK1 in complex with potent inhibitors.

Lazarus MB, Novotny CJ, Shokat KM.

ACS Chem Biol. 2015 Jan 16;10(1):257-61. doi: 10.1021/cb500835z. Epub 2015 Jan 6.

PMID:
25551253
17.

Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on α-synuclein.

Dhungel N, Eleuteri S, Li LB, Kramer NJ, Chartron JW, Spencer B, Kosberg K, Fields JA, Stafa K, Adame A, Lashuel H, Frydman J, Shen K, Masliah E, Gitler AD.

Neuron. 2015 Jan 7;85(1):76-87. doi: 10.1016/j.neuron.2014.11.027. Epub 2014 Dec 18. Erratum in: Neuron. 2015 Feb 4;85(3):657.

PMID:
25533483
18.

The neurology of mTOR.

Lipton JO, Sahin M.

Neuron. 2014 Oct 22;84(2):275-91. doi: 10.1016/j.neuron.2014.09.034. Epub 2014 Oct 22. Review.

PMID:
25374355
19.

Acinus integrates AKT1 and subapoptotic caspase activities to regulate basal autophagy.

Nandi N, Tyra LK, Stenesen D, Krämer H.

J Cell Biol. 2014 Oct 27;207(2):253-68. doi: 10.1083/jcb.201404028. Epub 2014 Oct 20.

20.

Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.

McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong WX, Yue Z.

PLoS Genet. 2014 Oct 2;10(10):e1004626. doi: 10.1371/journal.pgen.1004626. eCollection 2014 Oct.

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