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Items: 1 to 20 of 24


KINATEST-ID: a pipeline to develop phosphorylation-dependent terbium sensitizing kinase assays.

Lipchik AM, Perez M, Bolton S, Dumrongprechachan V, Ouellette SB, Cui W, Parker LL.

J Am Chem Soc. 2015 Feb 25;137(7):2484-94. doi: 10.1021/ja507164a. Epub 2015 Feb 17.


Systematic analysis of the phosphoproteome and kinase-substrate networks in the mouse testis.

Qi L, Liu Z, Wang J, Cui Y, Guo Y, Zhou T, Zhou Z, Guo X, Xue Y, Sha J.

Mol Cell Proteomics. 2014 Dec;13(12):3626-38. doi: 10.1074/mcp.M114.039073. Epub 2014 Oct 7.


Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics.

Xue L, Wang P, Cao P, Zhu JK, Tao WA.

Mol Cell Proteomics. 2014 Nov;13(11):3199-210. doi: 10.1074/mcp.O114.038588. Epub 2014 Jul 14.


Structural basis for phosphorylation and lysine acetylation cross-talk in a kinase motif associated with myocardial ischemia and cardioprotection.

Parker BL, Shepherd NE, Trefely S, Hoffman NJ, White MY, Engholm-Keller K, Hambly BD, Larsen MR, James DE, Cordwell SJ.

J Biol Chem. 2014 Sep 12;289(37):25890-906. doi: 10.1074/jbc.M114.556035. Epub 2014 Jul 9. Erratum in: J Biol Chem. 2014 Dec 5;289(49):33875.


Comprehensive characterization of (S)GTP-binding proteins by orthogonal quantitative (S)GTP-affinity profiling and (S)GTP/GTP competition assays.

Xiao Y, Ji D, Guo L, Wang Y.

Anal Chem. 2014 May 6;86(9):4550-8. doi: 10.1021/ac500588q. Epub 2014 Apr 11.


Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid.

Ræder H, McAllister FE, Tjora E, Bhatt S, Haldorsen I, Hu J, Willems SM, Vesterhus M, El Ouaamari A, Liu M, Ræder MB, Immervoll H, Hoem D, Dimcevski G, Njølstad PR, Molven A, Gygi SP, Kulkarni RN.

Diabetes. 2014 Jan;63(1):259-69. doi: 10.2337/db13-1012. Epub 2013 Sep 23.


Signal transduction in cerebral arteries after subarachnoid hemorrhage-a phosphoproteomic approach.

Parker BL, Larsen MR, Edvinsson LI, Povlsen GK.

J Cereb Blood Flow Metab. 2013 Aug;33(8):1259-69. doi: 10.1038/jcbfm.2013.78. Epub 2013 May 29.


Identification of a metabolizing enzyme in human kidney by proteomic correlation profiling.

Sakurai H, Kubota K, Inaba S, Takanaka K, Shinagawa A.

Mol Cell Proteomics. 2013 Aug;12(8):2313-23. doi: 10.1074/mcp.M112.023853. Epub 2013 May 14.


Mass spectrometry based method to increase throughput for kinome analyses using ATP probes.

McAllister FE, Niepel M, Haas W, Huttlin E, Sorger PK, Gygi SP.

Anal Chem. 2013 May 7;85(9):4666-74. doi: 10.1021/ac303478g. Epub 2013 Apr 22.


Determining target engagement in living systems.

Simon GM, Niphakis MJ, Cravatt BF.

Nat Chem Biol. 2013 Apr;9(4):200-5. doi: 10.1038/nchembio.1211. No abstract available.


Protein analysis by shotgun/bottom-up proteomics.

Zhang Y, Fonslow BR, Shan B, Baek MC, Yates JR 3rd.

Chem Rev. 2013 Apr 10;113(4):2343-94. doi: 10.1021/cr3003533. Epub 2013 Feb 26. Review. No abstract available.


Time-resolved luminescence detection of spleen tyrosine kinase activity through terbium sensitization.

Lipchik AM, Parker LL.

Anal Chem. 2013 Mar 5;85(5):2582-8. doi: 10.1021/ac3023422. Epub 2013 Feb 15.


The revolution and evolution of shotgun proteomics for large-scale proteome analysis.

Yates JR 3rd.

J Am Chem Soc. 2013 Feb 6;135(5):1629-40. doi: 10.1021/ja3094313. Epub 2013 Jan 16.


Temporal profiling of lapatinib-suppressed phosphorylation signals in EGFR/HER2 pathways.

Imami K, Sugiyama N, Imamura H, Wakabayashi M, Tomita M, Taniguchi M, Ueno T, Toi M, Ishihama Y.

Mol Cell Proteomics. 2012 Dec;11(12):1741-57. doi: 10.1074/mcp.M112.019919. Epub 2012 Sep 10.


Photocleavable peptide-oligonucleotide conjugates for protein kinase assays by MALDI-TOF MS.

Zhou G, Khan F, Dai Q, Sylvester JE, Kron SJ.

Mol Biosyst. 2012 Sep;8(9):2395-404. Epub 2012 Jul 6.


Phosphoproteomic analysis of leukemia cells under basal and drug-treated conditions identifies markers of kinase pathway activation and mechanisms of resistance.

Alcolea MP, Casado P, Rodríguez-Prados JC, Vanhaesebroeck B, Cutillas PR.

Mol Cell Proteomics. 2012 Aug;11(8):453-66. doi: 10.1074/mcp.M112.017483. Epub 2012 Apr 29.


FLEXIQinase, a mass spectrometry-based assay, to unveil multikinase mechanisms.

Singh SA, Winter D, Bilimoria PM, Bonni A, Steen H, Steen JA.

Nat Methods. 2012 Apr 8;9(5):504-8. doi: 10.1038/nmeth.1970.


Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates.

Xue L, Wang WH, Iliuk A, Hu L, Galan JA, Yu S, Hans M, Geahlen RL, Tao WA.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5615-20. doi: 10.1073/pnas.1119418109. Epub 2012 Mar 26.


Purification and identification of activating enzymes of CS-0777, a selective sphingosine 1-phosphate receptor 1 modulator, in erythrocytes.

Yonesu K, Kubota K, Tamura M, Inaba S, Honda T, Yahara C, Watanabe N, Matsuoka T, Nara F.

J Biol Chem. 2011 Jul 15;286(28):24765-75. doi: 10.1074/jbc.M110.217299. Epub 2011 May 25.


Phosphoproteomics in cancer.

Harsha HC, Pandey A.

Mol Oncol. 2010 Dec;4(6):482-95. doi: 10.1016/j.molonc.2010.09.004. Epub 2010 Sep 26. Review.

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