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Results: 17

1.

The unusual monomer recognition of guanine-containing mixed sequence DNA by a dithiophene heterocyclic diamidine.

Munde M, Kumar A, Peixoto P, Depauw S, Ismail MA, Farahat AA, Paul A, Say MV, David-Cordonnier MH, Boykin DW, Wilson WD.

Biochemistry. 2014 Feb 25;53(7):1218-27. doi: 10.1021/bi401582t. Epub 2014 Feb 13.

PMID:
24495039
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

BAALC expression: a suitable marker for prognostic risk stratification and detection of residual disease in cytogenetically normal acute myeloid leukemia.

Weber S, Alpermann T, Dicker F, Jeromin S, Nadarajah N, Eder C, Fasan A, Kohlmann A, Meggendorfer M, Haferlach C, Kern W, Haferlach T, Schnittger S.

Blood Cancer J. 2014 Jan 10;4:e173. doi: 10.1038/bcj.2013.71.

PMID:
24413067
[PubMed]
Free PMC Article
3.

Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia.

Goldberg L, Tijssen MR, Birger Y, Hannah RL, Kinston SJ, Schütte J, Beck D, Knezevic K, Schiby G, Jacob-Hirsch J, Biran A, Kloog Y, Marcucci G, Bloomfield CD, Aplan PD, Pimanda JE, Göttgens B, Izraeli S.

Blood. 2013 Oct 10;122(15):2694-703. doi: 10.1182/blood-2013-01-477133. Epub 2013 Aug 23.

PMID:
23974202
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Human BDH2, an anti-apoptosis factor, is a novel poor prognostic factor for de novo cytogenetically normal acute myeloid leukemia.

Yang WC, Tsai WC, Lin PM, Yang MY, Liu YC, Chang CS, Yu WH, Lin SF.

J Biomed Sci. 2013 Aug 14;20:58. doi: 10.1186/1423-0127-20-58.

PMID:
23941109
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Normal karyotype is a poor prognostic factor in myeloid leukemia of Down syndrome: a retrospective, international study.

Blink M, Zimmermann M, von Neuhoff C, Reinhardt D, de Haas V, Hasle H, O'Brien MM, Stark B, Tandonnet J, Pession A, Tousovska K, Cheuk DK, Kudo K, Taga T, Rubnitz JE, Haltrich I, Balwierz W, Pieters R, Forestier E, Johansson B, van den Heuvel-Eibrink MM, Zwaan CM.

Haematologica. 2014 Feb;99(2):299-307. doi: 10.3324/haematol.2013.089425. Epub 2013 Aug 9.

PMID:
23935021
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A standardized microarray assay for the independent gene expression markers in AML: EVI1 and BAALC.

Brand J, van Vliet MH, de Best L, Valk PJ, Viëtor HE, Löwenberg B, van Beers EH.

Exp Hematol Oncol. 2013 Mar 6;2(1):7. doi: 10.1186/2162-3619-2-7.

PMID:
23497432
[PubMed]
Free PMC Article
7.

ERG transcriptional networks in primary acute leukemia cells implicate a role for ERG in deregulated kinase signaling.

Bock J, Mochmann LH, Schlee C, Farhadi-Sartangi N, Göllner S, Müller-Tidow C, Baldus CD.

PLoS One. 2013;8(1):e52872. doi: 10.1371/journal.pone.0052872. Epub 2013 Jan 3.

PMID:
23300998
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Molecular prognostic factors in cytogenetically normal acute myeloid leukemia.

Walker A, Marcucci G.

Expert Rev Hematol. 2012 Oct;5(5):547-58. doi: 10.1586/ehm.12.45. Review.

PMID:
23146058
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines.

Nhili R, Peixoto P, Depauw S, Flajollet S, Dezitter X, Munde MM, Ismail MA, Kumar A, Farahat AA, Stephens CE, Duterque-Coquillaud M, David Wilson W, Boykin DW, David-Cordonnier MH.

Nucleic Acids Res. 2013 Jan 7;41(1):125-38. doi: 10.1093/nar/gks971. Epub 2012 Oct 23.

PMID:
23093599
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia.

Martens JH, Mandoli A, Simmer F, Wierenga BJ, Saeed S, Singh AA, Altucci L, Vellenga E, Stunnenberg HG.

Blood. 2012 Nov 8;120(19):4038-48. doi: 10.1182/blood-2012-05-429050. Epub 2012 Sep 14.

PMID:
22983443
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

New strategies in acute myeloid leukemia: redefining prognostic markers to guide therapy.

Khan I, Altman JK, Licht JD.

Clin Cancer Res. 2012 Oct 1;18(19):5163-71. doi: 10.1158/1078-0432.CCR-12-0313. Epub 2012 Aug 14.

PMID:
22893630
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Heritable polymorphism predisposes to high BAALC expression in acute myeloid leukemia.

Eisfeld AK, Marcucci G, Liyanarachchi S, Döhner K, Schwind S, Maharry K, Leffel B, Döhner H, Radmacher MD, Bloomfield CD, Tanner SM, de la Chapelle A.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6668-73. doi: 10.1073/pnas.1203756109. Epub 2012 Apr 9.

PMID:
22493267
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Low expression of MN1 associates with better treatment response in older patients with de novo cytogenetically normal acute myeloid leukemia.

Schwind S, Marcucci G, Kohlschmidt J, Radmacher MD, Mrózek K, Maharry K, Becker H, Metzeler KH, Whitman SP, Wu YZ, Powell BL, Baer MR, Kolitz JE, Carroll AJ, Larson RA, Caligiuri MA, Bloomfield CD.

Blood. 2011 Oct 13;118(15):4188-98. doi: 10.1182/blood-2011-06-357764. Epub 2011 Aug 9.

PMID:
21828125
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Impact of molecular prognostic factors in cytogenetically normal acute myeloid leukemia at diagnosis and relapse.

Walker A, Marcucci G.

Haematologica. 2011 May;96(5):640-3. doi: 10.3324/haematol.2011.042739. No abstract available.

PMID:
21531946
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia.

Balgobind BV, Van den Heuvel-Eibrink MM, De Menezes RX, Reinhardt D, Hollink IH, Arentsen-Peters ST, van Wering ER, Kaspers GJ, Cloos J, de Bont ES, Cayuela JM, Baruchel A, Meyer C, Marschalek R, Trka J, Stary J, Beverloo HB, Pieters R, Zwaan CM, den Boer ML.

Haematologica. 2011 Feb;96(2):221-30. doi: 10.3324/haematol.2010.029660. Epub 2010 Oct 22.

PMID:
20971820
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.

Schwind S, Marcucci G, Maharry K, Radmacher MD, Mrózek K, Holland KB, Margeson D, Becker H, Whitman SP, Wu YZ, Metzeler KH, Powell BL, Kolitz JE, Carter TH, Moore JO, Baer MR, Carroll AJ, Caligiuri MA, Larson RA, Bloomfield CD.

Blood. 2010 Dec 16;116(25):5660-9. doi: 10.1182/blood-2010-06-290536. Epub 2010 Sep 14.

PMID:
20841507
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.

Marcucci G, Maharry K, Wu YZ, Radmacher MD, Mrózek K, Margeson D, Holland KB, Whitman SP, Becker H, Schwind S, Metzeler KH, Powell BL, Carter TH, Kolitz JE, Wetzler M, Carroll AJ, Baer MR, Caligiuri MA, Larson RA, Bloomfield CD.

J Clin Oncol. 2010 May 10;28(14):2348-55. doi: 10.1200/JCO.2009.27.3730. Epub 2010 Apr 5.

PMID:
20368543
[PubMed - indexed for MEDLINE]
Free PMC Article
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