Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 31

1.

FGFR1 Kinase Inhibitors: Close Regioisomers Adopt Divergent Binding Modes and Display Distinct Biophysical Signatures.

Klein T, Tucker J, Holdgate GA, Norman RA, Breeze AL.

ACS Med Chem Lett. 2013 Dec 6;5(2):166-71. doi: 10.1021/ml4004205. eCollection 2014 Feb 13.

PMID:
24900792
[PubMed]
Free PMC Article
2.

Structural mimicry of a-loop tyrosine phosphorylation by a pathogenic FGF receptor 3 mutation.

Huang Z, Chen H, Blais S, Neubert TA, Li X, Mohammadi M.

Structure. 2013 Oct 8;21(10):1889-96. doi: 10.1016/j.str.2013.07.017. Epub 2013 Aug 22.

PMID:
23972473
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Quantification of shape and cell polarity reveals a novel mechanism underlying malformations resulting from related FGF mutations during facial morphogenesis.

Li X, Young NM, Tropp S, Hu D, Xu Y, Hallgrímsson B, Marcucio RS.

Hum Mol Genet. 2013 Dec 20;22(25):5160-72. doi: 10.1093/hmg/ddt369. Epub 2013 Aug 1.

PMID:
23906837
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

FGFR1 mutations cause Hartsfield syndrome, the unique association of holoprosencephaly and ectrodactyly.

Simonis N, Migeotte I, Lambert N, Perazzolo C, de Silva DC, Dimitrov B, Heinrichs C, Janssens S, Kerr B, Mortier G, Van Vliet G, Lepage P, Casimir G, Abramowicz M, Smits G, Vilain C.

J Med Genet. 2013 Sep;50(9):585-92. doi: 10.1136/jmedgenet-2013-101603. Epub 2013 Jun 28.

PMID:
23812909
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Tyrosine kinase BMX phosphorylates phosphotyrosine-primed motif mediating the activation of multiple receptor tyrosine kinases.

Chen S, Jiang X, Gewinner CA, Asara JM, Simon NI, Cai C, Cantley LC, Balk SP.

Sci Signal. 2013 May 28;6(277):ra40. doi: 10.1126/scisignal.2003936.

PMID:
23716717
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Phosphorylation of serine 779 in fibroblast growth factor receptor 1 and 2 by protein kinase C(epsilon) regulates Ras/mitogen-activated protein kinase signaling and neuronal differentiation.

Lonic A, Powell JA, Kong Y, Thomas D, Holien JK, Truong N, Parker MW, Guthridge MA.

J Biol Chem. 2013 May 24;288(21):14874-85. doi: 10.1074/jbc.M112.421669. Epub 2013 Apr 5.

PMID:
23564461
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Identification of a new interaction mode between the Src homology 2 domain of C-terminal Src kinase (Csk) and Csk-binding protein/phosphoprotein associated with glycosphingolipid microdomains.

Tanaka H, Akagi K, Oneyama C, Tanaka M, Sasaki Y, Kanou T, Lee YH, Yokogawa D, Dobenecker MW, Nakagawa A, Okada M, Ikegami T.

J Biol Chem. 2013 May 24;288(21):15240-54. doi: 10.1074/jbc.M112.439075. Epub 2013 Apr 2.

PMID:
23548896
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Deciphering Phosphotyrosine-Dependent Signaling Networks in Cancer by SH2 Profiling.

Machida K, Khenkhar M, Nollau P.

Genes Cancer. 2012 May;3(5-6):353-61. doi: 10.1177/1947601912459048.

PMID:
23226573
[PubMed]
Free PMC Article
9.

Phosphotyrosine recognition domains: the typical, the atypical and the versatile.

Kaneko T, Joshi R, Feller SM, Li SS.

Cell Commun Signal. 2012 Nov 7;10(1):32. doi: 10.1186/1478-811X-10-32.

PMID:
23134684
[PubMed]
Free PMC Article
10.

Src binds cortactin through an SH2 domain cystine-mediated linkage.

Evans JV, Ammer AG, Jett JE, Bolcato CA, Breaux JC, Martin KH, Culp MV, Gannett PM, Weed SA.

J Cell Sci. 2012 Dec 15;125(Pt 24):6185-97. doi: 10.1242/jcs.121046. Epub 2012 Oct 24.

PMID:
23097045
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Structural and functional integration of the PLCγ interaction domains critical for regulatory mechanisms and signaling deregulation.

Bunney TD, Esposito D, Mas-Droux C, Lamber E, Baxendale RW, Martins M, Cole A, Svergun D, Driscoll PC, Katan M.

Structure. 2012 Dec 5;20(12):2062-75. doi: 10.1016/j.str.2012.09.005. Epub 2012 Oct 11.

PMID:
23063561
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Evolution of SH2 domains and phosphotyrosine signalling networks.

Liu BA, Nash PD.

Philos Trans R Soc Lond B Biol Sci. 2012 Sep 19;367(1602):2556-73. doi: 10.1098/rstb.2012.0107. Review.

PMID:
22889907
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Serine phosphorylation of the insulin-like growth factor I (IGF-1) receptor C-terminal tail restrains kinase activity and cell growth.

Kelly GM, Buckley DA, Kiely PA, Adams DR, O'Connor R.

J Biol Chem. 2012 Aug 10;287(33):28180-94. doi: 10.1074/jbc.M112.385757. Epub 2012 Jun 8.

PMID:
22685298
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

High-throughput analysis of peptide-binding modules.

Liu BA, Engelmann BW, Nash PD.

Proteomics. 2012 May;12(10):1527-46. doi: 10.1002/pmic.201100599. Review.

PMID:
22610655
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Perspective: Dynamics of receptor tyrosine kinase signaling complexes.

Mayer BJ.

FEBS Lett. 2012 Aug 14;586(17):2575-9. doi: 10.1016/j.febslet.2012.05.002. Epub 2012 May 11. Review.

PMID:
22584051
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The phospholipase C isozymes and their regulation.

Gresset A, Sondek J, Harden TK.

Subcell Biochem. 2012;58:61-94. doi: 10.1007/978-94-007-3012-0_3. Review.

PMID:
22403074
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Fibronectin induces endothelial cell migration through β1 integrin and Src-dependent phosphorylation of fibroblast growth factor receptor-1 at tyrosines 653/654 and 766.

Zou L, Cao S, Kang N, Huebert RC, Shah VH.

J Biol Chem. 2012 Mar 2;287(10):7190-202. doi: 10.1074/jbc.M111.304972. Epub 2012 Jan 14.

PMID:
22247553
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav.

Chen CH, Martin VA, Gorenstein NM, Geahlen RL, Post CB.

Mol Cell Biol. 2011 Jul;31(14):2984-96. doi: 10.1128/MCB.05043-11. Epub 2011 May 23.

PMID:
21606197
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Structure of lipid kinase p110β/p85β elucidates an unusual SH2-domain-mediated inhibitory mechanism.

Zhang X, Vadas O, Perisic O, Anderson KE, Clark J, Hawkins PT, Stephens LR, Williams RL.

Mol Cell. 2011 Mar 4;41(5):567-78. doi: 10.1016/j.molcel.2011.01.026.

PMID:
21362552
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Structural basis for the interaction between the growth factor-binding protein GRB10 and the E3 ubiquitin ligase NEDD4.

Huang Q, Szebenyi DM.

J Biol Chem. 2010 Dec 31;285(53):42130-9. doi: 10.1074/jbc.M110.143412. Epub 2010 Oct 26.

PMID:
20980250
[PubMed - indexed for MEDLINE]
Free PMC Article
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk