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Results: 12

Cited In for PubMed (Select 19651900)


Icariin induces synoviolin expression through NFE2L1 to protect neurons from ER stress-induced apoptosis.

Li F, Gao B, Dong H, Shi J, Fang D.

PLoS One. 2015 Mar 25;10(3):e0119955. doi: 10.1371/journal.pone.0119955. eCollection 2015.


WWP2 is overexpressed in human oral cancer, determining tumor size and poor prognosis in patients: downregulation of WWP2 inhibits the AKT signaling and tumor growth in mice.

Fukumoto C, Nakashima D, Kasamatsu A, Unozawa M, Shida-Sakazume T, Higo M, Ogawara K, Yokoe H, Shiiba M, Tanzawa H, Uzawa K.

Oncoscience. 2014 Nov 28;1(12):807-20. eCollection 2014.


Paip1, an effective stimulator of translation initiation, is targeted by WWP2 for ubiquitination and degradation.

Lv Y, Zhang K, Gao H.

Mol Cell Biol. 2014 Dec;34(24):4513-22. doi: 10.1128/MCB.00524-14. Epub 2014 Sep 29. Erratum in: Mol Cell Biol. 2015 Feb;35(3):631.


Histone deacetylase sirtuin 1 deacetylates IRF1 protein and programs dendritic cells to control Th17 protein differentiation during autoimmune inflammation.

Yang H, Lee SM, Gao B, Zhang J, Fang D.

J Biol Chem. 2013 Dec 27;288(52):37256-66. doi: 10.1074/jbc.M113.527531. Epub 2013 Nov 8.


Ndfip1 enforces a requirement for CD28 costimulation by limiting IL-2 production.

Ramos-Hernández N, Ramon HE, Beal AM, Laroche A, Dekleva EA, Oliver PM.

J Immunol. 2013 Aug 15;191(4):1536-46. doi: 10.4049/jimmunol.1203571. Epub 2013 Jul 12.


E3 ligase WWP2 negatively regulates TLR3-mediated innate immune response by targeting TRIF for ubiquitination and degradation.

Yang Y, Liao B, Wang S, Yan B, Jin Y, Shu HB, Wang YY.

Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5115-20. doi: 10.1073/pnas.1220271110. Epub 2013 Mar 11.


Analysis of sirtuin 1 expression reveals a molecular explanation of IL-2-mediated reversal of T-cell tolerance.

Gao B, Kong Q, Kemp K, Zhao YS, Fang D.

Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):899-904. doi: 10.1073/pnas.1118462109. Epub 2012 Jan 4.


Viral and cellular requirements for the budding of feline endogenous retrovirus RD-114.

Fukuma A, Abe M, Urata S, Yoshikawa R, Morikawa Y, Miyazawa T, Yasuda J.

Virol J. 2011 Dec 14;8:540. doi: 10.1186/1743-422X-8-540.


c-Abl-mediated tyrosine phosphorylation of the T-bet DNA-binding domain regulates CD4+ T-cell differentiation and allergic lung inflammation.

Chen A, Lee SM, Gao B, Shannon S, Zhu Z, Fang D.

Mol Cell Biol. 2011 Aug;31(16):3445-56. doi: 10.1128/MCB.05383-11. Epub 2011 Jun 20.


WWP2 is an E3 ubiquitin ligase for PTEN.

Maddika S, Kavela S, Rani N, Palicharla VR, Pokorny JL, Sarkaria JN, Chen J.

Nat Cell Biol. 2011 Jun;13(6):728-33. doi: 10.1038/ncb2240. Epub 2011 May 1.


The type III histone deacetylase Sirt1 protein suppresses p300-mediated histone H3 lysine 56 acetylation at Bclaf1 promoter to inhibit T cell activation.

Kong S, Kim SJ, Sandal B, Lee SM, Gao B, Zhang DD, Fang D.

J Biol Chem. 2011 May 13;286(19):16967-75. doi: 10.1074/jbc.M111.218206. Epub 2011 Mar 22.


Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes.

Lee SM, Yang H, Tartar DM, Gao B, Luo X, Ye SQ, Zaghouani H, Fang D.

Diabetologia. 2011 May;54(5):1136-46. doi: 10.1007/s00125-011-2064-1. Epub 2011 Feb 22.

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