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Items: 1 to 20 of 803

1.

"Inflammaging" as a Druggable Target: A Senescence-Associated Secretory Phenotype-Centered View of Type 2 Diabetes.

Prattichizzo F, De Nigris V, La Sala L, Procopio AD, Olivieri F, Ceriello A.

Oxid Med Cell Longev. 2016;2016:1810327. doi: 10.1155/2016/1810327. Epub 2016 Jun 1. Review.

2.

Autophagy and Tubular Cell Death in the Kidney.

Havasi A, Dong Z.

Semin Nephrol. 2016 May;36(3):174-88. doi: 10.1016/j.semnephrol.2016.03.005. Review.

PMID:
27339383
3.

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice.

Mitchell SJ, Madrigal-Matute J, Scheibye-Knudsen M, Fang E, Aon M, González-Reyes JA, Cortassa S, Kaushik S, Gonzalez-Freire M, Patel B, Wahl D, Ali A, Calvo-Rubio M, Burón MI, Guiterrez V, Ward TM, Palacios HH, Cai H, Frederick DW, Hine C, Broeskamp F, Habering L, Dawson J, Beasley TM, Wan J, Ikeno Y, Hubbard G, Becker KG, Zhang Y, Bohr VA, Longo DL, Navas P, Ferrucci L, Sinclair DA, Cohen P, Egan JM, Mitchell JR, Baur JA, Allison DB, Anson RM, Villalba JM, Madeo F, Cuervo AM, Pearson KJ, Ingram DK, Bernier M, de Cabo R.

Cell Metab. 2016 Jun 14;23(6):1093-112. doi: 10.1016/j.cmet.2016.05.027.

PMID:
27304509
4.

From Ancient Pathways to Aging Cells-Connecting Metabolism and Cellular Senescence.

Wiley CD, Campisi J.

Cell Metab. 2016 Jun 14;23(6):1013-21. doi: 10.1016/j.cmet.2016.05.010. Review.

PMID:
27304503
5.

The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging.

Kennedy BK, Lamming DW.

Cell Metab. 2016 Jun 14;23(6):990-1003. doi: 10.1016/j.cmet.2016.05.009. Review.

PMID:
27304501
6.

Four-week rapamycin treatment improves muscular dystrophy in a fukutin-deficient mouse model of dystroglycanopathy.

Foltz SJ, Luan J, Call JA, Patel A, Peissig KB, Fortunato MJ, Beedle AM.

Skelet Muscle. 2016 Jun 2;6:20. doi: 10.1186/s13395-016-0091-9. eCollection 2016.

7.

Adaptations to chronic rapamycin in mice.

Dodds SG, Livi CB, Parihar M, Hsu HK, Benavides AD, Morris J, Javors M, Strong R, Christy B, Hasty P, Sharp ZD.

Pathobiol Aging Age Relat Dis. 2016 May 27;6:31688. doi: 10.3402/pba.v6.31688. eCollection 2016.

8.

Rapamycin: An InhibiTOR of Aging Emerges From the Soil of Easter Island.

Arriola Apelo SI, Lamming DW.

J Gerontol A Biol Sci Med Sci. 2016 Jul;71(7):841-9. doi: 10.1093/gerona/glw090. Epub 2016 May 21. Review.

PMID:
27208895
9.

Pharmacological Strategies to Retard Cardiovascular Aging.

Alfaras I, Di Germanio C, Bernier M, Csiszar A, Ungvari Z, Lakatta EG, de Cabo R.

Circ Res. 2016 May 13;118(10):1626-42. doi: 10.1161/CIRCRESAHA.116.307475. Review.

PMID:
27174954
10.

Aging and Autophagy in the Heart.

Shirakabe A, Ikeda Y, Sciarretta S, Zablocki DK, Sadoshima J.

Circ Res. 2016 May 13;118(10):1563-76. doi: 10.1161/CIRCRESAHA.116.307474. Review.

PMID:
27174950
11.

Geroscience approaches to increase healthspan and slow aging.

Melov S.

F1000Res. 2016 Apr 29;5. pii: F1000 Faculty Rev-785. doi: 10.12688/f1000research.7583.1. eCollection 2016. Review.

12.
13.

microRNA-496 - A new, potentially aging-relevant regulator of mTOR.

Rubie C, Kölsch K, Halajda B, Eichler H, Wagenpfeil S, Roemer K, Glanemann M.

Cell Cycle. 2016 Apr 17;15(8):1108-16. doi: 10.1080/15384101.2016.1158360.

PMID:
27097372
14.

Intermittent Administration of Rapamycin Extends the Life Span of Female C57BL/6J Mice.

Arriola Apelo SI, Pumper CP, Baar EL, Cummings NE, Lamming DW.

J Gerontol A Biol Sci Med Sci. 2016 Jul;71(7):876-81. doi: 10.1093/gerona/glw064. Epub 2016 Apr 18.

PMID:
27091134
15.

Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules.

Kumar S, Lombard DB.

F1000Res. 2016 Mar 29;5. pii: F1000 Faculty Rev-406. doi: 10.12688/f1000research.7821.1. eCollection 2016. Review.

16.

Tetrahydrohyperforin (IDN5706) targets the endoplasmic reticulum for autophagy activation: potential mechanism for Alzheimer's disease therapy.

González A, Cavieres VA, Inestrosa NC, Burgos PV.

Neural Regen Res. 2016 Feb;11(2):242-3. doi: 10.4103/1673-5374.177728. No abstract available.

17.

Evolutionary ecology of aging: time to reconcile field and laboratory research.

Reichard M.

Ecol Evol. 2016 Mar 28;6(9):2988-3000. doi: 10.1002/ece3.2093. eCollection 2016 May.

18.

Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis.

Castillo-Quan JI, Li L, Kinghorn KJ, Ivanov DK, Tain LS, Slack C, Kerr F, Nespital T, Thornton J, Hardy J, Bjedov I, Partridge L.

Cell Rep. 2016 Apr 19;15(3):638-50. doi: 10.1016/j.celrep.2016.03.041. Epub 2016 Apr 7.

19.

Inhibition of the Mechanistic Target of Rapamycin (mTOR)-Rapamycin and Beyond.

Lamming DW.

Cold Spring Harb Perspect Med. 2016 May 2;6(5). pii: a025924. doi: 10.1101/cshperspect.a025924. Review.

20.

Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning.

Liu D, Bordicchia M, Zhang C, Fang H, Wei W, Li JL, Guilherme A, Guntur K, Czech MP, Collins S.

J Clin Invest. 2016 May 2;126(5):1704-16. doi: 10.1172/JCI83532. Epub 2016 Mar 28.

PMID:
27018708
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