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Items: 19


In Vitro Expansion of Bone Marrow Derived Mesenchymal Stem Cells Alters DNA Double Strand Break Repair of Etoposide Induced DNA Damage.

Hare I, Gencheva M, Evans R, Fortney J, Piktel D, Vos JA, Howell D, Gibson LF.

Stem Cells Int. 2016;2016:8270464. doi: 10.1155/2016/8270464. Epub 2016 Jan 6.


FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4.

Zhang Q, Karnak D, Tan M, Lawrence TS, Morgan MA, Sun Y.

Mol Cell. 2016 Feb 4;61(3):419-33. doi: 10.1016/j.molcel.2015.12.010. Epub 2016 Jan 7.


Harmine suppresses homologous recombination repair and inhibits proliferation of hepatoma cells.

Zhang L, Zhang F, Zhang W, Chen L, Gao N, Men Y, Xu X, Jiang Y.

Cancer Biol Ther. 2015;16(11):1585-92. doi: 10.1080/15384047.2015.1078021. Epub 2015 Sep 18.


Mutant IDH1-driven cellular transformation increases RAD51-mediated homologous recombination and temozolomide resistance.

Ohba S, Mukherjee J, See WL, Pieper RO.

Cancer Res. 2014 Sep 1;74(17):4836-44. doi: 10.1158/0008-5472.CAN-14-0924. Epub 2014 Jul 17.


A small molecule inhibitor of human RAD51 potentiates breast cancer cell killing by therapeutic agents in mouse xenografts.

Huang F, Mazin AV.

PLoS One. 2014 Jun 27;9(6):e100993. doi: 10.1371/journal.pone.0100993. eCollection 2014.


Utilization of Rad51C promoter for transcriptional targeting of cancer cells.

Cao Y, Xu Y, Zhang L, Li Z, Jiang Y, Tian X, Seluanov A, Gorbunova V, Mao Z.

Oncotarget. 2014 Apr 15;5(7):1805-11.


Doubling down on the PI3K-AKT-mTOR pathway enhances the antitumor efficacy of PARP inhibitor in triple negative breast cancer model beyond BRCA-ness.

De P, Sun Y, Carlson JH, Friedman LS, Leyland-Jones BR, Dey N.

Neoplasia. 2014 Jan;16(1):43-72. Erratum in: Neoplasia. 2014 Apr;16(4):375. Neoplasia. 2014 Apr;16(4):375.


RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.

Bohgaki M, Bohgaki T, El Ghamrasni S, Srikumar T, Maire G, Panier S, Fradet-Turcotte A, Stewart GS, Raught B, Hakem A, Hakem R.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):20982-7. doi: 10.1073/pnas.1320302111. Epub 2013 Dec 9.


Changes in the expression of miR-381 and miR-495 are inversely associated with the expression of the MDR1 gene and development of multi-drug resistance.

Xu Y, Ohms SJ, Li Z, Wang Q, Gong G, Hu Y, Mao Z, Shannon MF, Fan JY.

PLoS One. 2013 Nov 26;8(11):e82062. doi: 10.1371/journal.pone.0082062. eCollection 2013.


Riccardin D Exerts Its Antitumor Activity by Inducing DNA Damage in PC-3 Prostate Cancer Cells In Vitro and In Vivo.

Hu Z, Kong F, Si M, Tian K, Yu LX, Young CY, Yuan H, Lou H.

PLoS One. 2013 Sep 17;8(9):e74387. doi: 10.1371/journal.pone.0074387. eCollection 2013.


Evaluation of DNA damage in COPD patients and its correlation with polymorphisms in repair genes.

da Silva AL, da Rosa HT, Karnopp TE, Charlier CF, Ellwanger JH, Moura DJ, Possuelo LG, Valim AR, Guecheva TN, Henriques JA.

BMC Med Genet. 2013 Sep 20;14:93. doi: 10.1186/1471-2350-14-93.


Polymorphism of UBC9 gene encoding the SUMO-E2-conjugating enzyme and breast cancer risk.

Wozniak K, Krupa R, Synowiec E, Morawiec Z.

Pathol Oncol Res. 2014 Jan;20(1):67-72. doi: 10.1007/s12253-013-9659-4. Epub 2013 Jul 20.


Effect of EME1 exon variant Ile350Thr on risk and early onset of breast cancer in southern Chinese women.

Zhao J, Liu L, Zhang A, Chen Q, Fang W, Zeng L, Lu J.

J Biomed Res. 2013 May;27(3):193-201. doi: 10.7555/JBR.27.20130013. Epub 2013 Apr 15.


The interconnectedness of cancer cell signaling.

Rehemtulla A.

Neoplasia. 2011 Dec;13(12):1183-93.


Analysis of DNA double-strand break (DSB) repair in mammalian cells.

Seluanov A, Mao Z, Gorbunova V.

J Vis Exp. 2010 Sep 8;(43). pii: 2002. doi: 10.3791/2002.


Targeting abnormal DNA double strand break repair in cancer.

Rassool FV, Tomkinson AE.

Cell Mol Life Sci. 2010 Nov;67(21):3699-710. doi: 10.1007/s00018-010-0493-5. Epub 2010 Aug 10. Review.


Three-dimensionally specific inhibition of DNA repair-related genes by activated KRAS in colon crypt model.

Tsunoda T, Takashima Y, Fujimoto T, Koyanagi M, Yoshida Y, Doi K, Tanaka Y, Kuroki M, Sasazuki T, Shirasawa S.

Neoplasia. 2010 May;12(5):397-404.


The War on Cancer rages on.

Rehemtulla A.

Neoplasia. 2009 Dec;11(12):1252-63.

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