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Cited In for PubMed (Select 19497884)


Bacterial and fungal pattern recognition receptors in homologous innate signaling pathways of insects and mammals.

Stokes BA, Yadav S, Shokal U, Smith LC, Eleftherianos I.

Front Microbiol. 2015 Jan 28;6:19. doi: 10.3389/fmicb.2015.00019. eCollection 2015. Review.


The caspase-8 homolog Dredd cleaves Imd and Relish but is not inhibited by p35.

Kim CH, Paik D, Rus F, Silverman N.

J Biol Chem. 2014 Jul 18;289(29):20092-101. doi: 10.1074/jbc.M113.544841. Epub 2014 Jun 2.


Loss of Trabid, a new negative regulator of the drosophila immune-deficiency pathway at the level of TAK1, reduces life span.

Fernando MD, Kounatidis I, Ligoxygakis P.

PLoS Genet. 2014 Feb 20;10(2):e1004117. doi: 10.1371/journal.pgen.1004117. eCollection 2014 Feb.


The shrimp IKK-NF-κB signaling pathway regulates antimicrobial peptide expression and may be subverted by white spot syndrome virus to facilitate viral gene expression.

Wang PH, Gu ZH, Wan DH, Liu BD, Huang XD, Weng SP, Yu XQ, He JG.

Cell Mol Immunol. 2013 Sep;10(5):423-36. doi: 10.1038/cmi.2013.30. Epub 2013 Aug 19.


Mutations in the IMD pathway and mustard counter Vibrio cholerae suppression of intestinal stem cell division in Drosophila.

Wang Z, Hang S, Purdy AE, Watnick PI.

MBio. 2013 Jun 18;4(3):e00337-13. doi: 10.1128/mBio.00337-13.


The Drosophila IMD pathway in the activation of the humoral immune response.

Kleino A, Silverman N.

Dev Comp Immunol. 2014 Jan;42(1):25-35. doi: 10.1016/j.dci.2013.05.014. Epub 2013 May 27. Review.


Viruses and antiviral immunity in Drosophila.

Xu J, Cherry S.

Dev Comp Immunol. 2014 Jan;42(1):67-84. doi: 10.1016/j.dci.2013.05.002. Epub 2013 May 13. Review.


Ecdysone triggered PGRP-LC expression controls Drosophila innate immunity.

Rus F, Flatt T, Tong M, Aggarwal K, Okuda K, Kleino A, Yates E, Tatar M, Silverman N.

EMBO J. 2013 May 29;32(11):1626-38. doi: 10.1038/emboj.2013.100. Epub 2013 May 7.


Conventional and non-conventional Drosophila Toll signaling.

Lindsay SA, Wasserman SA.

Dev Comp Immunol. 2014 Jan;42(1):16-24. doi: 10.1016/j.dci.2013.04.011. Epub 2013 Apr 28. Review.


Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation.

Silke J, Meier P.

Cold Spring Harb Perspect Biol. 2013 Feb 1;5(2). pii: a008730. doi: 10.1101/cshperspect.a008730. Review.


Drosophila EYA regulates the immune response against DNA through an evolutionarily conserved threonine phosphatase motif.

Liu X, Sano T, Guan Y, Nagata S, Hoffmann JA, Fukuyama H.

PLoS One. 2012;7(8):e42725. doi: 10.1371/journal.pone.0042725. Epub 2012 Aug 15.


Serine/threonine acetylation of TGFβ-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling.

Paquette N, Conlon J, Sweet C, Rus F, Wilson L, Pereira A, Rosadini CV, Goutagny N, Weber AN, Lane WS, Shaffer SA, Maniatis S, Fitzgerald KA, Stuart L, Silverman N.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12710-5. doi: 10.1073/pnas.1008203109. Epub 2012 Jul 16.


Drosophila as a model system to unravel the layers of innate immunity to infection.

Kounatidis I, Ligoxygakis P.

Open Biol. 2012 May;2(5):120075. doi: 10.1098/rsob.120075. Review.


Regulating the regulators: the pervasive effects of Pol II pausing on stimulus-responsive gene networks.

Gilchrist DA, Fromm G, dos Santos G, Pham LN, McDaniel IE, Burkholder A, Fargo DC, Adelman K.

Genes Dev. 2012 May 1;26(9):933-44. doi: 10.1101/gad.187781.112.


Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling.

Meinander A, Runchel C, Tenev T, Chen L, Kim CH, Ribeiro PS, Broemer M, Leulier F, Zvelebil M, Silverman N, Meier P.

EMBO J. 2012 Jun 13;31(12):2770-83. doi: 10.1038/emboj.2012.121. Epub 2012 May 1.


The Drosophila protein mustard tailors the innate immune response activated by the immune deficiency pathway.

Wang Z, Berkey CD, Watnick PI.

J Immunol. 2012 Apr 15;188(8):3993-4000. doi: 10.4049/jimmunol.1103301. Epub 2012 Mar 16.


The Drosophila melanogaster host model.

Igboin CO, Griffen AL, Leys EJ.

J Oral Microbiol. 2012;4. doi: 10.3402/jom.v4i0.10368. Epub 2012 Feb 21.


Differentially expressed profiles in the larval testes of Wolbachia infected and uninfected Drosophila.

Zheng Y, Wang JL, Liu C, Wang CP, Walker T, Wang YF.

BMC Genomics. 2011 Dec 6;12:595. doi: 10.1186/1471-2164-12-595.


Toll-8/Tollo negatively regulates antimicrobial response in the Drosophila respiratory epithelium.

Akhouayri I, Turc C, Royet J, Charroux B.

PLoS Pathog. 2011 Oct;7(10):e1002319. doi: 10.1371/journal.ppat.1002319. Epub 2011 Oct 13.


Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway.

Boyer L, Magoc L, Dejardin S, Cappillino M, Paquette N, Hinault C, Charriere GM, Ip WK, Fracchia S, Hennessy E, Erturk-Hasdemir D, Reichhart JM, Silverman N, Lacy-Hulbert A, Stuart LM.

Immunity. 2011 Oct 28;35(4):536-49. doi: 10.1016/j.immuni.2011.08.015. Epub 2011 Oct 20.

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