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The role of poly(ADP-ribosyl)ation in DNA damage response and cancer chemotherapy.

Li M, Yu X.

Oncogene. 2014 Sep 15. doi: 10.1038/onc.2014.295. [Epub ahead of print] Review.


A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response.

Blasius M, Wagner SA, Choudhary C, Bartek J, Jackson SP.

Genes Dev. 2014 Sep 15;28(18):1977-82. doi: 10.1101/gad.246272.114. Epub 2014 Sep 4.


Achieving peptide binding specificity and promiscuity by loops: case of the forkhead-associated domain.

Huang YM, Chang CE.

PLoS One. 2014 May 28;9(5):e98291. doi: 10.1371/journal.pone.0098291. eCollection 2014.


Conditional genetic interactions of RTT107, SLX4, and HRQ1 reveal dynamic networks upon DNA damage in S. cerevisiae.

Leung GP, Aristizabal MJ, Krogan NJ, Kobor MS.

G3 (Bethesda). 2014 Apr 2;4(6):1059-69. doi: 10.1534/g3.114.011205.


Nuclear pore complex evolution: a trypanosome Mlp analogue functions in chromosomal segregation but lacks transcriptional barrier activity.

Holden JM, Koreny L, Obado S, Ratushny AV, Chen WM, Chiang JH, Kelly S, Chait BT, Aitchison JD, Rout MP, Field MC.

Mol Biol Cell. 2014 May;25(9):1421-36. doi: 10.1091/mbc.E13-12-0750. Epub 2014 Mar 5.


The checkpoint-dependent nuclear accumulation of Rho1p exchange factor Rgf1p is important for tolerance to chronic replication stress.

Muñoz S, Manjón E, García P, Sunnerhagen P, Sánchez Y.

Mol Biol Cell. 2014 Apr;25(7):1137-50. doi: 10.1091/mbc.E13-11-0689. Epub 2014 Jan 29.


The breast cancer susceptibility genes (BRCA) in breast and ovarian cancers.

Paul A, Paul S.

Front Biosci (Landmark Ed). 2014 Jan 1;19:605-18. Review.


DNA-PK target identification reveals novel links between DNA repair signaling and cytoskeletal regulation.

Kotula E, Faigle W, Berthault N, Dingli F, Loew D, Sun JS, Dutreix M, Quanz M.

PLoS One. 2013 Nov 25;8(11):e80313. doi: 10.1371/journal.pone.0080313. eCollection 2013.


CK1 is required for a mitotic checkpoint that delays cytokinesis.

Johnson AE, Chen JS, Gould KL.

Curr Biol. 2013 Oct 7;23(19):1920-6. doi: 10.1016/j.cub.2013.07.077. Epub 2013 Sep 19.


Tumor protein D52 represents a negative regulator of ATM protein levels.

Chen Y, Kamili A, Hardy JR, Groblewski GE, Khanna KK, Byrne JA.

Cell Cycle. 2013 Sep 15;12(18):3083-97. doi: 10.4161/cc.26146. Epub 2013 Aug 21.


The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response.

Li M, Lu LY, Yang CY, Wang S, Yu X.

Genes Dev. 2013 Aug 15;27(16):1752-68. doi: 10.1101/gad.226357.113.


Structural mechanisms underlying signaling in the cellular response to DNA double strand breaks.

Mermershtain I, Glover JN.

Mutat Res. 2013 Oct;750(1-2):15-22. doi: 10.1016/j.mrfmmm.2013.07.004. Epub 2013 Jul 27. Review.


PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition.

Kasahara K, Goto H, Izawa I, Kiyono T, Watanabe N, Elowe S, Nigg EA, Inagaki M.

Nat Commun. 2013;4:1882. doi: 10.1038/ncomms2879.


The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair.

Wang H, Shi LZ, Wong CC, Han X, Hwang PY, Truong LN, Zhu Q, Shao Z, Chen DJ, Berns MW, Yates JR 3rd, Chen L, Wu X.

PLoS Genet. 2013;9(2):e1003277. doi: 10.1371/journal.pgen.1003277. Epub 2013 Feb 28.


Chromatin modifications and the DNA damage response to ionizing radiation.

Kumar R, Horikoshi N, Singh M, Gupta A, Misra HS, Albuquerque K, Hunt CR, Pandita TK.

Front Oncol. 2013 Jan 22;2:214. doi: 10.3389/fonc.2012.00214. eCollection 2012.


Charting the landscape of tandem BRCT domain-mediated protein interactions.

Woods NT, Mesquita RD, Sweet M, Carvalho MA, Li X, Liu Y, Nguyen H, Thomas CE, Iversen ES Jr, Marsillac S, Karchin R, Koomen J, Monteiro AN.

Sci Signal. 2012 Sep 18;5(242):rs6.


Directed evolution of the forkhead-associated domain to generate anti-phosphospecific reagents by phage display.

Pershad K, Wypisniak K, Kay BK.

J Mol Biol. 2012 Nov 23;424(1-2):88-103. doi: 10.1016/j.jmb.2012.09.006. Epub 2012 Sep 15.


Characterization of proteins secreted by pancreatic cancer cells with anticancer drug treatment in vitro.

Takata T, Ishigaki Y, Shimasaki T, Tsuchida H, Motoo Y, Hayashi A, Tomosugi N.

Oncol Rep. 2012 Dec;28(6):1968-76. doi: 10.3892/or.2012.2020. Epub 2012 Sep 5.


Telomere structure and telomerase in health and disease (review).

Gomez DE, Armando RG, Farina HG, Menna PL, Cerrudo CS, Ghiringhelli PD, Alonso DF.

Int J Oncol. 2012 Nov;41(5):1561-9. doi: 10.3892/ijo.2012.1611. Epub 2012 Aug 29. Review.

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