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Genomic Alteration in Head and Neck Squamous Cell Carcinoma (HNSCC) Cell Lines Inferred from Karyotyping, Molecular Cytogenetics, and Array Comparative Genomic Hybridization.

Singchat W, Hitakomate E, Rerkarmnuaychoke B, Suntronpong A, Fu B, Bodhisuwan W, Peyachoknagul S, Yang F, Koontongkaew S, Srikulnath K.

PLoS One. 2016 Aug 8;11(8):e0160901. doi: 10.1371/journal.pone.0160901. eCollection 2016.


Classical pathology and mutational load of breast cancer - integration of two worlds.

Budczies J, Bockmayr M, Denkert C, Klauschen F, Lennerz JK, Györffy B, Dietel M, Loibl S, Weichert W, Stenzinger A.

J Pathol Clin Res. 2015 Jul 20;1(4):225-38. doi: 10.1002/cjp2.25. eCollection 2015 Oct.


The genetics of nodal marginal zone lymphoma.

Spina V, Khiabanian H, Messina M, Monti S, Cascione L, Bruscaggin A, Spaccarotella E, Holmes AB, Arcaini L, Lucioni M, Tabbò F, Zairis S, Diop F, Cerri M, Chiaretti S, Marasca R, Ponzoni M, Deaglio S, Ramponi A, Tiacci E, Pasqualucci L, Paulli M, Falini B, Inghirami G, Bertoni F, Foà R, Rabadan R, Gaidano G, Rossi D.

Blood. 2016 Sep 8;128(10):1362-73. doi: 10.1182/blood-2016-02-696757. Epub 2016 Jun 22.


Integrated Genomics for Pinpointing Survival Loci within Arm-Level Somatic Copy Number Alterations.

Roy DM, Walsh LA, Desrichard A, Huse JT, Wu W, Gao J, Bose P, Lee W, Chan TA.

Cancer Cell. 2016 May 9;29(5):737-50. doi: 10.1016/j.ccell.2016.03.025.


Frequent HRAS Mutations in Malignant Ectomesenchymoma: Overlapping Genetic Abnormalities With Embryonal Rhabdomyosarcoma.

Huang SC, Alaggio R, Sung YS, Chen CL, Zhang L, Kao YC, Agaram NP, Wexler LH, Antonescu CR.

Am J Surg Pathol. 2016 Jul;40(7):876-85. doi: 10.1097/PAS.0000000000000612.


Transgelin increases metastatic potential of colorectal cancer cells in vivo and alters expression of genes involved in cell motility.

Zhou HM, Fang YY, Weinberger PM, Ding LL, Cowell JK, Hudson FZ, Ren M, Lee JR, Chen QK, Su H, Dynan WS, Lin Y.

BMC Cancer. 2016 Feb 4;16:55. doi: 10.1186/s12885-016-2105-8.


Increased metastasis with loss of E2F2 in Myc-driven tumors.

Yuwanita I, Barnes D, Monterey MD, O'Reilly S, Andrechek ER.

Oncotarget. 2015 Nov 10;6(35):38210-24. doi: 10.18632/oncotarget.5690.


PTPRD gene associated with blood pressure response to atenolol and resistant hypertension.

Gong Y, McDonough CW, Beitelshees AL, El Rouby N, Hiltunen TP, O'Connell JR, Padmanabhan S, Langaee TY, Hall K, Schmidt SO, Curry RW Jr, Gums JG, Donner KM, Kontula KK, Bailey KR, Boerwinkle E, Takahashi A, Tanaka T, Kubo M, Chapman AB, Turner ST, Pepine CJ, Cooper-DeHoff RM, Johnson JA.

J Hypertens. 2015 Nov;33(11):2278-85. doi: 10.1097/HJH.0000000000000714.


Loss-of-Function PTPRD Mutations Lead to Increased STAT3 Activation and Sensitivity to STAT3 Inhibition in Head and Neck Cancer.

Peyser ND, Du Y, Li H, Lui V, Xiao X, Chan TA, Grandis JR.

PLoS One. 2015 Aug 12;10(8):e0135750. doi: 10.1371/journal.pone.0135750. eCollection 2015.


Genome-Wide Loss of Heterozygosity and DNA Copy Number Aberration in HPV-Negative Oral Squamous Cell Carcinoma and Their Associations with Disease-Specific Survival.

Chen C, Zhang Y, Loomis MM, Upton MP, Lohavanichbutr P, Houck JR, Doody DR, Mendez E, Futran N, Schwartz SM, Wang P.

PLoS One. 2015 Aug 6;10(8):e0135074. doi: 10.1371/journal.pone.0135074. eCollection 2015.


Abundant copy-number loss of CYCLOPS and STOP genes in gastric adenocarcinoma.

Cutcutache I, Wu AY, Suzuki Y, McPherson JR, Lei Z, Deng N, Zhang S, Wong WK, Soo KC, Chan WH, Ooi LL, Welsch R, Tan P, Rozen SG.

Gastric Cancer. 2016 Apr;19(2):453-65. doi: 10.1007/s10120-015-0514-z. Epub 2015 Jul 24.


Prognostic implication of PTPRH hypomethylation in non-small cell lung cancer.

Sato T, Soejima K, Arai E, Hamamoto J, Yasuda H, Arai D, Ishioka K, Ohgino K, Naoki K, Kohno T, Tsuta K, Watanabe S, Kanai Y, Betsuyaku T.

Oncol Rep. 2015 Sep;34(3):1137-45. doi: 10.3892/or.2015.4082. Epub 2015 Jun 25.


PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes.

Chen YT, Lin WD, Liao WL, Lin YJ, Chang JG, Tsai FJ.

Oncotarget. 2015 May 30;6(15):12997-3005.


Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity.

Kim HS, Li A, Ahn S, Song H, Zhang W.

Sci Rep. 2014 Dec 5;4:7330. doi: 10.1038/srep07330.


Reduced expression of PTPRD correlates with poor prognosis in gastric adenocarcinoma.

Wang D, Wang L, Zhou J, Pan J, Qian W, Fu J, Zhang G, Zhu Y, Liu C, Wang C, Jin Z, He Z, Wu J, Shi B.

PLoS One. 2014 Nov 20;9(11):e113754. doi: 10.1371/journal.pone.0113754. eCollection 2014.


Receptor-type protein tyrosine phosphatases in cancer.

Du Y, Grandis JR.

Chin J Cancer. 2015 Feb;34(2):61-9. doi: 10.5732/cjc.014.10146. Epub 2014 Oct 17. Review.


Host genetic variants and gene expression patterns associated with Epstein-Barr virus copy number in lymphoblastoid cell lines.

Houldcroft CJ, Petrova V, Liu JZ, Frampton D, Anderson CA, Gall A, Kellam P.

PLoS One. 2014 Oct 7;9(10):e108384. doi: 10.1371/journal.pone.0108384. eCollection 2014.


Missing-in-Metastasis regulates cell motility and invasion via PTPδ-mediated changes in SRC activity.

Chaudhary F, Lucito R, Tonks NK.

Biochem J. 2015 Jan 1;465(1):89-101. doi: 10.1042/BJ20140573.


Genetic alterations of protein tyrosine phosphatases in human cancers.

Zhao S, Sedwick D, Wang Z.

Oncogene. 2015 Jul 23;34(30):3885-94. doi: 10.1038/onc.2014.326. Epub 2014 Sep 29. Review.


NF-κB and STAT3 in glioblastoma: therapeutic targets coming of age.

Gray GK, McFarland BC, Nozell SE, Benveniste EN.

Expert Rev Neurother. 2014 Nov;14(11):1293-306. doi: 10.1586/14737175.2014.964211. Epub 2014 Sep 29. Review.

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