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Results: 11

1.

Novel preclinical models of topical PrEP pharmacodynamics provide rationale for combination of drugs with complementary properties.

Mesquita PM, Srinivasan P, Johnson TJ, Rastogi R, Evans-Strickfaden T, Kay MS, Buckheit KW, Buckheit RW Jr, Smith JM, Kiser PF, Herold BC.

Retrovirology. 2013 Oct 24;10:113. doi: 10.1186/1742-4690-10-113.

PMID:
24156604
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges.

Smith JM, Rastogi R, Teller RS, Srinivasan P, Mesquita PM, Nagaraja U, McNicholl JM, Hendry RM, Dinh CT, Martin A, Herold BC, Kiser PF.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16145-50. doi: 10.1073/pnas.1311355110. Epub 2013 Sep 16.

PMID:
24043812
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Vaginal rings for delivery of HIV microbicides.

Malcolm RK, Fetherston SM, McCoy CF, Boyd P, Major I.

Int J Womens Health. 2012;4:595-605. doi: 10.2147/IJWH.S36282. Epub 2012 Nov 20.

PMID:
23204872
[PubMed]
Free PMC Article
4.

Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220.

Fetherston SM, Geer L, Veazey RS, Goldman L, Murphy DJ, Ketas TJ, Klasse PJ, Blois S, La Colla P, Moore JP, Malcolm RK.

J Antimicrob Chemother. 2013 Feb;68(2):394-403. doi: 10.1093/jac/dks415. Epub 2012 Oct 28. Erratum in: J Antimicrob Chemother. 2013 Jun;68(6):1451.

PMID:
23109186
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A 90-day tenofovir reservoir intravaginal ring for mucosal HIV prophylaxis.

Johnson TJ, Clark MR, Albright TH, Nebeker JS, Tuitupou AL, Clark JT, Fabian J, McCabe RT, Chandra N, Doncel GF, Friend DR, Kiser PF.

Antimicrob Agents Chemother. 2012 Dec;56(12):6272-83. doi: 10.1128/AAC.01431-12. Epub 2012 Sep 24.

PMID:
23006751
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Safety and pharmacokinetics of intravaginal rings delivering tenofovir in pig-tailed macaques.

Moss JA, Malone AM, Smith TJ, Butkyavichene I, Cortez C, Gilman J, Kennedy S, Kopin E, Nguyen C, Sinha P, Hendry RM, Guenthner P, Holder A, Martin A, McNicholl J, Mitchell J, Pau CP, Srinivasan P, Smith JM, Baum MM.

Antimicrob Agents Chemother. 2012 Nov;56(11):5952-60. doi: 10.1128/AAC.01198-12. Epub 2012 Sep 10.

PMID:
22964245
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques.

Malcolm RK, Veazey RS, Geer L, Lowry D, Fetherston SM, Murphy DJ, Boyd P, Major I, Shattock RJ, Klasse PJ, Doyle LA, Rasmussen KK, Goldman L, Ketas TJ, Moore JP.

Antimicrob Agents Chemother. 2012 May;56(5):2251-8. doi: 10.1128/AAC.05810-11. Epub 2012 Feb 13.

PMID:
22330914
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Safe and sustained vaginal delivery of pyrimidinedione HIV-1 inhibitors from polyurethane intravaginal rings.

Johnson TJ, Srinivasan P, Albright TH, Watson-Buckheit K, Rabe L, Martin A, Pau CP, Hendry RM, Otten R, McNicholl J, Buckheit R Jr, Smith J, Kiser PF.

Antimicrob Agents Chemother. 2012 Mar;56(3):1291-9. doi: 10.1128/AAC.05721-11. Epub 2011 Dec 12.

PMID:
22155820
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring.

Moss JA, Malone AM, Smith TJ, Kennedy S, Kopin E, Nguyen C, Gilman J, Butkyavichene I, Vincent KL, Motamedi M, Friend DR, Clark MR, Baum MM.

Antimicrob Agents Chemother. 2012 Feb;56(2):875-82. doi: 10.1128/AAC.05662-11. Epub 2011 Nov 28.

PMID:
22123689
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Development of a pigtail macaque model of sexually transmitted infection/HIV coinfection using Chlamydia trachomatis, Trichomonas vaginalis, and SHIV(SF162P3).

Henning T, Fakile Y, Phillips C, Sweeney E, Mitchell J, Patton D, Sturdevant G, Caldwell HD, Secor WE, Papp J, Hendry RM, McNicholl J, Kersh E.

J Med Primatol. 2011 Aug;40(4):214-23. doi: 10.1111/j.1600-0684.2011.00488.x.

PMID:
21781129
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Microbial biofilms on the surface of intravaginal rings worn in non-human primates.

Gunawardana M, Moss JA, Smith TJ, Kennedy S, Kopin E, Nguyen C, Malone AM, Rabe L, Schaudinn C, Webster P, Srinivasan P, Sweeney ED, Smith JM, Baum MM.

J Med Microbiol. 2011 Jun;60(Pt 6):828-37. doi: 10.1099/jmm.0.028225-0. Epub 2011 Mar 10.

PMID:
21393449
[PubMed - indexed for MEDLINE]
Free PMC Article

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