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Results: 17

Cited In for PubMed (Select 19460155)

1.

Tyrosine phosphorylation of Dbl regulates GTPase signaling.

Gupta M, Qi X, Thakur V, Manor D.

J Biol Chem. 2014 Jun 13;289(24):17195-202. doi: 10.1074/jbc.M114.573782. Epub 2014 Apr 28.

2.

Modification of p115RhoGEF Ser(330) regulates its RhoGEF activity.

Chow CR, Suzuki N, Kawamura T, Hamakubo T, Kozasa T.

Cell Signal. 2013 Nov;25(11):2085-92. doi: 10.1016/j.cellsig.2013.06.012. Epub 2013 Jun 29.

3.

Structural basis for autoinhibition of the guanine nucleotide exchange factor FARP2.

He X, Kuo YC, Rosche TJ, Zhang X.

Structure. 2013 Mar 5;21(3):355-64. doi: 10.1016/j.str.2013.01.001. Epub 2013 Jan 31.

4.

Structural determinants of RGS-RhoGEF signaling critical to Entamoeba histolytica pathogenesis.

Bosch DE, Kimple AJ, Manning AJ, Muller RE, Willard FS, Machius M, Rogers SL, Siderovski DP.

Structure. 2013 Jan 8;21(1):65-75. doi: 10.1016/j.str.2012.11.012. Epub 2012 Dec 20.

5.

The role of actin filament dynamics in the myogenic response of cerebral resistance arteries.

Walsh MP, Cole WC.

J Cereb Blood Flow Metab. 2013 Jan;33(1):1-12. doi: 10.1038/jcbfm.2012.144. Epub 2012 Oct 17. Review.

6.

Activation of p115-RhoGEF requires direct association of Gα13 and the Dbl homology domain.

Chen Z, Guo L, Hadas J, Gutowski S, Sprang SR, Sternweis PC.

J Biol Chem. 2012 Jul 20;287(30):25490-500. doi: 10.1074/jbc.M111.333716. Epub 2012 Jun 1.

7.

Essential role of the NH2-terminal region of Cdc24 guanine nucleotide exchange factor in its initial polarized localization in Saccharomyces cerevisiae.

Fujimura-Kamada K, Hirai T, Tanaka K.

Eukaryot Cell. 2012 Jan;11(1):2-15. doi: 10.1128/EC.05146-11. Epub 2011 Nov 23.

8.

Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13.

Kozasa T, Hajicek N, Chow CR, Suzuki N.

J Biochem. 2011 Oct;150(4):357-69. doi: 10.1093/jb/mvr105. Epub 2011 Aug 26. Review.

9.

Insights into the molecular activation mechanism of the RhoA-specific guanine nucleotide exchange factor, PDZRhoGEF.

Bielnicki JA, Shkumatov AV, Derewenda U, Somlyo AV, Svergun DI, Derewenda ZS.

J Biol Chem. 2011 Oct 7;286(40):35163-75. doi: 10.1074/jbc.M111.270918. Epub 2011 Aug 4.

10.

Identification of a negative regulatory region for the exchange activity and characterization of T332I mutant of Rho guanine nucleotide exchange factor 10 (ARHGEF10).

Chaya T, Shibata S, Tokuhara Y, Yamaguchi W, Matsumoto H, Kawahara I, Kogo M, Ohoka Y, Inagaki S.

J Biol Chem. 2011 Aug 26;286(34):29511-20. doi: 10.1074/jbc.M111.236810. Epub 2011 Jun 30.

11.

Identification of critical residues in G(alpha)13 for stimulation of p115RhoGEF activity and the structure of the G(alpha)13-p115RhoGEF regulator of G protein signaling homology (RH) domain complex.

Hajicek N, Kukimoto-Niino M, Mishima-Tsumagari C, Chow CR, Shirouzu M, Terada T, Patel M, Yokoyama S, Kozasa T.

J Biol Chem. 2011 Jun 10;286(23):20625-36. doi: 10.1074/jbc.M110.201392. Epub 2011 Apr 20.

12.

Mechanistic insights into specificity, activity, and regulatory elements of the regulator of G-protein signaling (RGS)-containing Rho-specific guanine nucleotide exchange factors (GEFs) p115, PDZ-RhoGEF (PRG), and leukemia-associated RhoGEF (LARG).

Jaiswal M, Gremer L, Dvorsky R, Haeusler LC, Cirstea IC, Uhlenbrock K, Ahmadian MR.

J Biol Chem. 2011 May 20;286(20):18202-12. doi: 10.1074/jbc.M111.226431. Epub 2011 Mar 28.

13.

Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF.

Chen Z, Guo L, Sprang SR, Sternweis PC.

Protein Sci. 2011 Jan;20(1):107-17. doi: 10.1002/pro.542.

14.

Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.

Chen Z, Medina F, Liu MY, Thomas C, Sprang SR, Sternweis PC.

J Biol Chem. 2010 Jul 2;285(27):21070-81. doi: 10.1074/jbc.M110.122549. Epub 2010 Apr 29.

15.

Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors.

Aittaleb M, Boguth CA, Tesmer JJ.

Mol Pharmacol. 2010 Feb;77(2):111-25. doi: 10.1124/mol.109.061234. Epub 2009 Oct 30. Review.

16.

Semaphorin 4D signaling requires the recruitment of phospholipase C gamma into the plexin-B1 receptor complex.

Swiercz JM, Worzfeld T, Offermanns S.

Mol Cell Biol. 2009 Dec;29(23):6321-34. doi: 10.1128/MCB.00103-09. Epub 2009 Oct 5.

17.

The solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoA.

Cierpicki T, Bielnicki J, Zheng M, Gruszczyk J, Kasterka M, Petoukhov M, Zhang A, Fernandez EJ, Svergun DI, Derewenda U, Bushweller JH, Derewenda ZS.

Protein Sci. 2009 Oct;18(10):2067-79. doi: 10.1002/pro.219.

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