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Items: 1 to 20 of 159

1.

AMPK Activators as a Drug for Diabetes, Cancer and Cardiovascular Disease.

Goodman M, Liu Z, Zhu P, Li J.

Pharm Regul Aff. 2014 Jul;3(2). pii: 118. Epub 2014 Apr 3.

2.

AICAR reduces the collagen-stimulated secretion of PDGF-AB and release of soluble CD40 ligand from human platelets: Suppression of HSP27 phosphorylation via p44/p42 MAP kinase.

Tsujimoto M, Tokuda H, Kuroyanagi G, Yamamoto N, Kainuma S, Matsushima-Nishiwaki R, Onuma T, Iida Y, Kojima A, Sawada S, Doi T, Enomoto Y, Tanabe K, Akamatsu S, Iida H, Ogura S, Otsuka T, Kozawa O, Iwama T.

Exp Ther Med. 2016 Aug;12(2):1107-1112. Epub 2016 Jun 7.

3.

Creosote Bush (Larrea tridentata) Improves Insulin Sensitivity and Reduces Plasma and Hepatic Lipids in Hamsters Fed a High Fat and Cholesterol Diet.

Del Vecchyo-Tenorio G, Rodríguez-Cruz M, Andrade-Cetto A, Cárdenas-Vázquez R.

Front Pharmacol. 2016 Jun 28;7:194. doi: 10.3389/fphar.2016.00194. eCollection 2016.

4.

Features of an altered AMPK metabolic pathway in Gilbert's Syndrome, and its role in metabolic health.

Mölzer C, Wallner M, Kern C, Tosevska A, Schwarz U, Zadnikar R, Doberer D, Marculescu R, Wagner KH.

Sci Rep. 2016 Jul 21;6:30051. doi: 10.1038/srep30051.

5.

Ampelopsin Improves Insulin Resistance by Activating PPARγ and Subsequently Up-Regulating FGF21-AMPK Signaling Pathway.

Zhou Y, Wu Y, Qin Y, Liu L, Wan J, Zou L, Zhang Q, Zhu J, Mi M.

PLoS One. 2016 Jul 8;11(7):e0159191. doi: 10.1371/journal.pone.0159191. eCollection 2016.

6.

Ethanol extracts of chickpeas alter the total lipid content and expression levels of genes related to fatty acid metabolism in mouse 3T3-L1 adipocytes.

Shinohara S, Gu Y, Yang Y, Furuta Y, Tanaka M, Yue X, Wang W, Kitano M, Kimura H.

Int J Mol Med. 2016 Aug;38(2):574-84. doi: 10.3892/ijmm.2016.2654. Epub 2016 Jun 24.

7.

AMPK Phosphorylates Desnutrin/ATGL and Hormone-Sensitive Lipase To Regulate Lipolysis and Fatty Acid Oxidation within Adipose Tissue.

Kim SJ, Tang T, Abbott M, Viscarra JA, Wang Y, Sul HS.

Mol Cell Biol. 2016 Jun 29;36(14):1961-76. doi: 10.1128/MCB.00244-16. Print 2016 Jul 15.

PMID:
27185873
8.

Rhodiola crenulata extract regulates hepatic glycogen and lipid metabolism via activation of the AMPK pathway.

Lin KT, Hsu SW, Lai FY, Chang TC, Shi LS, Lee SY.

BMC Complement Altern Med. 2016 May 17;16:127. doi: 10.1186/s12906-016-1108-y.

9.

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function.

Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martínez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, Tóth M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Fekete C, Redwood C, Yeo GS, Heisler LK, Rutter GA, Smith MA, Withers DJ, Carling D, Sternick EB, Arch JR, Cawthorne MA, Watkins H, Ashrafian H.

Cell Metab. 2016 May 10;23(5):821-36. doi: 10.1016/j.cmet.2016.04.003. Epub 2016 Apr 28.

10.

Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK.

Yang YJ, Hu L, Xia YP, Jiang CY, Miao C, Yang CQ, Yuan M, Wang L.

J Neuroinflammation. 2016 Apr 19;13(1):84. doi: 10.1186/s12974-016-0550-6.

11.

Hydroxycinnamic acid derivatives: a potential class of natural compounds for the management of lipid metabolism and obesity.

Alam MA, Subhan N, Hossain H, Hossain M, Reza HM, Rahman MM, Ullah MO.

Nutr Metab (Lond). 2016 Apr 11;13:27. doi: 10.1186/s12986-016-0080-3. eCollection 2016. Review.

12.

Dietary walnut reduces hepatic triglyceride content in high-fat-fed mice via modulation of hepatic fatty acid metabolism and adipose tissue inflammation.

Choi Y, Abdelmegeed MA, Akbar M, Song BJ.

J Nutr Biochem. 2016 Apr;30:116-25. doi: 10.1016/j.jnutbio.2015.12.005. Epub 2016 Jan 6.

PMID:
27012628
13.

Metformin stimulates IGFBP-2 gene expression through PPARalpha in diabetic states.

Kang HS, Cho HC, Lee JH, Oh GT, Koo SH, Park BH, Lee IK, Choi HS, Song DK, Im SS.

Sci Rep. 2016 Mar 24;6:23665. doi: 10.1038/srep23665.

14.

β-aminoisobutyric acid attenuates hepatic endoplasmic reticulum stress and glucose/lipid metabolic disturbance in mice with type 2 diabetes.

Shi CX, Zhao MX, Shu XD, Xiong XQ, Wang JJ, Gao XY, Chen Q, Li YH, Kang YM, Zhu GQ.

Sci Rep. 2016 Feb 24;6:21924. doi: 10.1038/srep21924.

15.

Lysosomal integral membrane protein Sidt2 plays a vital role in insulin secretion.

Gao J, Yu C, Xiong Q, Zhang Y, Wang L.

Int J Clin Exp Pathol. 2015 Dec 1;8(12):15622-31. eCollection 2015.

16.

Diabetic conditions modulate the adenosine monophosphate-activated protein kinase of podocytes.

Ha TS, Park HY, Nam JA, Han GD.

Kidney Res Clin Pract. 2014 Mar;33(1):26-32. doi: 10.1016/j.krcp.2014.02.001. Epub 2014 Mar 17.

17.

Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet.

Slocum SL, Skoko JJ, Wakabayashi N, Aja S, Yamamoto M, Kensler TW, Chartoumpekis DV.

Arch Biochem Biophys. 2016 Feb 1;591:57-65. doi: 10.1016/j.abb.2015.11.040. Epub 2015 Dec 14.

PMID:
26701603
18.

Bardoxolone Methyl Prevents Mesenteric Fat Deposition and Inflammation in High-Fat Diet Mice.

Dinh CH, Szabo A, Yu Y, Camer D, Wang H, Huang XF.

ScientificWorldJournal. 2015;2015:549352. doi: 10.1155/2015/549352. Epub 2015 Nov 5.

19.

AICAR and Metformin Exert AMPK-dependent Effects on INS-1E Pancreatic β-cell Apoptosis via Differential Downstream Mechanisms.

Dai YL, Huang SL, Leng Y.

Int J Biol Sci. 2015 Sep 14;11(11):1272-80. doi: 10.7150/ijbs.12108. eCollection 2015.

20.

Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis.

Zhang H, Li Y, Hu J, Shen WJ, Singh M, Hou X, Bittner A, Bittner S, Cortez Y, Tabassum J, Kraemer FB, Azhar S.

PLoS One. 2015 Sep 22;10(9):e0138203. doi: 10.1371/journal.pone.0138203. eCollection 2015.

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