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In-Utero Low-Dose Irradiation Leads to Persistent Alterations in the Mouse Heart Proteome.

Bakshi MV, Azimzadeh O, Merl-Pham J, Verreet T, Hauck SM, Benotmane MA, Atkinson MJ, Tapio S.

PLoS One. 2016 Jun 8;11(6):e0156952. doi: 10.1371/journal.pone.0156952. eCollection 2016.


Scaffolded Antigens in Yeast Cell Particle Vaccines Provide Protection against Systemic Polyoma Virus Infection.

Tipper DJ, Szomolanyi-Tsuda E.

J Immunol Res. 2016;2016:2743292. doi: 10.1155/2016/2743292. Epub 2016 Apr 26.


Association of Common Genetic Variants in Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 with Type 2 Diabetes Mellitus in a Chinese Han Population.

Li TT, Qiao H, Tong HX, Zhuang TW, Wang TT.

Chin Med J (Engl). 2016 20th May;129(10):1179-1184. doi: 10.4103/0366-6999.181969.


Map4k4 Signaling Nodes in Metabolic and Cardiovascular Diseases.

Virbasius JV, Czech MP.

Trends Endocrinol Metab. 2016 Jul;27(7):484-92. doi: 10.1016/j.tem.2016.04.006. Epub 2016 May 6. Review.


Engineering nanomaterials to address cell-mediated inflammation in atherosclerosis.

Allen S, Liu YG, Scott E.

Regen Eng Transl Med. 2016 Mar;2(1):37-50. Epub 2016 Mar 3.


Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients.

Chuang HC, Wang JS, Lee IT, Sheu WH, Tan TH.

Oncotarget. 2016 Mar 8;7(10):10976-89. doi: 10.18632/oncotarget.7686.


Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts.

Specht CA, Lee CK, Huang H, Tipper DJ, Shen ZT, Lodge JK, Leszyk J, Ostroff GR, Levitz SM.

MBio. 2015 Dec 22;6(6):e01905-15. doi: 10.1128/mBio.01905-15.


Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis.

Roth Flach RJ, Skoura A, Matevossian A, Danai LV, Zheng W, Cortes C, Bhattacharya SK, Aouadi M, Hagan N, Yawe JC, Vangala P, Menendez LG, Cooper MP, Fitzgibbons TP, Buckbinder L, Czech MP.

Nat Commun. 2015 Dec 21;6:8995. doi: 10.1038/ncomms9995.


Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment.

Ammirati M, Bagley SW, Bhattacharya SK, Buckbinder L, Carlo AA, Conrad R, Cortes C, Dow RL, Dowling MS, El-Kattan A, Ford K, GuimarĂ£es CR, Hepworth D, Jiao W, LaPerle J, Liu S, Londregan A, Loria PM, Mathiowetz AM, Munchhof M, Orr ST, Petersen DN, Price DA, Skoura A, Smith AC, Wang J.

ACS Med Chem Lett. 2015 Oct 6;6(11):1128-33. doi: 10.1021/acsmedchemlett.5b00215. eCollection 2015 Nov 12.


Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route.

Murakami M, Nishina K, Watanabe C, Yoshida-Tanaka K, Piao W, Kuwahara H, Horikiri Y, Miyata K, Nishiyama N, Kataoka K, Yoshida M, Mizusawa H, Yokota T.

Sci Rep. 2015 Nov 23;5:17035. doi: 10.1038/srep17035.


Nanomedicine and drug delivery strategies for treatment of inflammatory bowel disease.

Takedatsu H, Mitsuyama K, Torimura T.

World J Gastroenterol. 2015 Oct 28;21(40):11343-52. doi: 10.3748/wjg.v21.i40.11343. Review.


Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug.

Miller MA, Zheng YR, Gadde S, Pfirschke C, Zope H, Engblom C, Kohler RH, Iwamoto Y, Yang KS, Askevold B, Kolishetti N, Pittet M, Lippard SJ, Farokhzad OC, Weissleder R.

Nat Commun. 2015 Oct 27;6:8692. doi: 10.1038/ncomms9692.


Drug delivery strategies and systems for HIV/AIDS pre-exposure prophylaxis and treatment.

Nelson AG, Zhang X, Ganapathi U, Szekely Z, Flexner CW, Owen A, Sinko PJ.

J Control Release. 2015 Dec 10;219:669-80. doi: 10.1016/j.jconrel.2015.08.042. Epub 2015 Aug 24.


Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis.

Ndubaku CO, Crawford TD, Chen H, Boggs JW, Drobnick J, Harris SF, Jesudason R, McNamara E, Nonomiya J, Sambrone A, Schmidt S, Smyczek T, Vitorino P, Wang L, Wu P, Yeung S, Chen J, Chen K, Ding CZ, Wang T, Xu Z, Gould SE, Murray LJ, Ye W.

ACS Med Chem Lett. 2015 Jun 29;6(8):913-8. doi: 10.1021/acsmedchemlett.5b00174. eCollection 2015 Aug 13.


Metabolic functions of FABPs--mechanisms and therapeutic implications.

Hotamisligil GS, Bernlohr DA.

Nat Rev Endocrinol. 2015 Oct;11(10):592-605. doi: 10.1038/nrendo.2015.122. Epub 2015 Aug 11. Review.


Digesting dietary miRNA therapeutics.

Yarmarkovich M, Hirschi KD.

Oncotarget. 2015 Jun 10;6(16):13848-9. No abstract available.


Biomaterial-mediated modification of the local inflammatory environment.

Browne S, Pandit A.

Front Bioeng Biotechnol. 2015 May 15;3:67. doi: 10.3389/fbioe.2015.00067. eCollection 2015. Review.


Efficient delivery of antigen to DCs using yeast-derived microparticles.

Pan Y, Li X, Kang T, Meng H, Chen Z, Yang L, Wu Y, Wei Y, Gou M.

Sci Rep. 2015 May 29;5:10687. doi: 10.1038/srep10687.


Translational Nano-Medicines: Targeted Therapeutic Delivery for Cancer and Inflammatory Diseases.

Talekar M, Tran TH, Amiji M.

AAPS J. 2015 Jul;17(4):813-27. doi: 10.1208/s12248-015-9772-2. Epub 2015 Apr 29. Review.

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