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Results: 19

1.

Axon degeneration and PGC-1α-mediated protection in a zebrafish model of α-synuclein toxicity.

O'Donnell KC, Lulla A, Stahl MC, Wheat ND, Bronstein JM, Sagasti A.

Dis Model Mech. 2014 May;7(5):571-82. doi: 10.1242/dmm.013185. Epub 2014 Mar 13.

PMID:
24626988
[PubMed - in process]
Free PMC Article
2.

The impact of mitochondrial DNA and nuclear genes related to mitochondrial functioning on the risk of Parkinson's disease.

Gaweda-Walerych K, Zekanowski C.

Curr Genomics. 2013 Dec;14(8):543-59. doi: 10.2174/1389202914666131210211033.

PMID:
24532986
[PubMed]
Free PMC Article
3.

Genome-wide analysis reveals coating of the mitochondrial genome by TFAM.

Wang YE, Marinov GK, Wold BJ, Chan DC.

PLoS One. 2013 Aug 26;8(8):e74513. doi: 10.1371/journal.pone.0074513. eCollection 2013.

PMID:
23991223
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice.

Thomas RR, Khan SM, Smigrodzki RM, Onyango IG, Dennis J, Khan OM, Portelli FR, Bennett JP Jr.

Aging (Albany NY). 2012 Sep;4(9):620-35.

PMID:
23075607
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mitochondrial gene therapy improves respiration, biogenesis, and transcription in G11778A Leber's hereditary optic neuropathy and T8993G Leigh's syndrome cells.

Iyer S, Bergquist K, Young K, Gnaiger E, Rao RR, Bennett JP Jr.

Hum Gene Ther. 2012 Jun;23(6):647-57. doi: 10.1089/hum.2011.177. Epub 2012 Apr 17.

PMID:
22390282
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Therapeutic potential of melatonin and its analogs in Parkinson's disease: focus on sleep and neuroprotection.

Srinivasan V, Cardinali DP, Srinivasan US, Kaur C, Brown GM, Spence DW, Hardeland R, Pandi-Perumal SR.

Ther Adv Neurol Disord. 2011 Sep;4(5):297-317. doi: 10.1177/1756285611406166.

PMID:
22010042
[PubMed]
Free PMC Article
7.

Role and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases.

Swerdlow RH.

Curr Pharm Des. 2011;17(31):3356-73. Review.

PMID:
21902672
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Designing an organellar postal service: delivery of macromolecules to mitochondria in intact cells.

Bruni F, Lightowlers RN.

Mol Ther. 2011 Aug;19(8):1404-5. doi: 10.1038/mt.2011.139. No abstract available.

PMID:
21804616
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Mitochondrial transformation: time for concerted action.

Lightowlers RN.

EMBO Rep. 2011 Jun;12(6):480-1. doi: 10.1038/embor.2011.93. No abstract available.

PMID:
21629303
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Does mitochondrial DNA play a role in Parkinson's disease? A review of cybrid and other supportive evidence.

Swerdlow RH.

Antioxid Redox Signal. 2012 May 1;16(9):950-64. doi: 10.1089/ars.2011.3948. Epub 2011 May 25. Review.

PMID:
21338319
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Leber's Hereditary Optic Neuropathy-Gene Therapy: From Benchtop to Bedside.

Koilkonda RD, Guy J.

J Ophthalmol. 2011;2011:179412. doi: 10.1155/2011/179412. Epub 2010 Dec 26.

PMID:
21253496
[PubMed]
Free PMC Article
12.

Re-engineering the mitochondrial genomes in mammalian cells.

Yoon YG, Koob MD, Yoo YH.

Anat Cell Biol. 2010 Jun;43(2):97-109. doi: 10.5115/acb.2010.43.2.97. Epub 2010 Jun 30.

PMID:
21189990
[PubMed]
Free PMC Article
13.

Leber hereditary optic neuropathy gene therapy clinical trial recruitment: year 1.

Lam BL, Feuer WJ, Abukhalil F, Porciatti V, Hauswirth WW, Guy J.

Arch Ophthalmol. 2010 Sep;128(9):1129-35. doi: 10.1001/archophthalmol.2010.201.

PMID:
20837795
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin.

Thomas RR, Khan SM, Portell FR, Smigrodzki RM, Bennett JP Jr.

Mitochondrion. 2011 Jan;11(1):108-18. doi: 10.1016/j.mito.2010.08.004. Epub 2010 Aug 18.

PMID:
20727424
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Induction of rapid and highly efficient expression of the human ND4 complex I subunit in the mouse visual system by self-complementary adeno-associated virus.

Koilkonda RD, Chou TH, Porciatti V, Hauswirth WW, Guy J.

Arch Ophthalmol. 2010 Jul;128(7):876-83. doi: 10.1001/archophthalmol.2010.135.

PMID:
20625049
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions.

Keeney PM, Bennett JP Jr.

Mol Neurodegener. 2010 May 26;5:21. doi: 10.1186/1750-1326-5-21.

PMID:
20504367
[PubMed]
Free PMC Article
17.

The Alzheimer's disease mitochondrial cascade hypothesis.

Swerdlow RH, Burns JM, Khan SM.

J Alzheimers Dis. 2010;20 Suppl 2:S265-79. doi: 10.3233/JAD-2010-100339. Review.

PMID:
20442494
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease.

Chu CT.

Hum Mol Genet. 2010 Apr 15;19(R1):R28-37. doi: 10.1093/hmg/ddq143. Epub 2010 Apr 12. Review.

PMID:
20385539
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

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