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Antitumor potential of the myotoxin BthTX-I from Bothrops jararacussu snake venom: evaluation of cell cycle alterations and death mechanisms induced in tumor cell lines.

Prinholato da Silva C, Costa TR, Paiva RM, Cintra AC, Menaldo DL, Antunes LM, Sampaio SV.

J Venom Anim Toxins Incl Trop Dis. 2015 Nov 3;21:44. doi: 10.1186/s40409-015-0044-5. eCollection 2015.


A legion of potential regulatory sRNAs exists beyond the typical microRNAs microcosm.

Jha A, Panzade G, Pandey R, Shankar R.

Nucleic Acids Res. 2015 Oct 15;43(18):8713-24. doi: 10.1093/nar/gkv871. Epub 2015 Sep 9.


Lipid analysis of eight human breast cancer cell lines with ToF-SIMS.

Robinson MA, Graham DJ, Morrish F, Hockenbery D, Gamble LJ.

Biointerphases. 2015 Jun 28;11(2):02A303. doi: 10.1116/1.4929633.


Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays.

Lee JA, Shinn P, Jaken S, Oliver S, Willard FS, Heidler S, Peery RB, Oler J, Chu S, Southall N, Dexheimer TS, Smallwood J, Huang R, Guha R, Jadhav A, Cox K, Austin CP, Simeonov A, Sittampalam GS, Husain S, Franklin N, Wild DJ, Yang JJ, Sutherland JJ, Thomas CJ.

PLoS One. 2015 Jul 15;10(7):e0130796. doi: 10.1371/journal.pone.0130796. eCollection 2015.


Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?

Robey RB, Weisz J, Kuemmerle NB, Salzberg AC, Berg A, Brown DG, Kubik L, Palorini R, Al-Mulla F, Al-Temaimi R, Colacci A, Mondello C, Raju J, Woodrick J, Scovassi AI, Singh N, Vaccari M, Roy R, Forte S, Memeo L, Salem HK, Amedei A, Hamid RA, Williams GP, Lowe L, Meyer J, Martin FL, Bisson WH, Chiaradonna F, Ryan EP.

Carcinogenesis. 2015 Jun;36 Suppl 1:S203-31. doi: 10.1093/carcin/bgv037. Review.


Chicken or the egg: Warburg effect and mitochondrial dysfunction.

Senyilmaz D, Teleman AA.

F1000Prime Rep. 2015 Apr 2;7:41. doi: 10.12703/P7-41. eCollection 2015. Review.


UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis.

Moon JS, Lee S, Park MA, Siempos II, Haslip M, Lee PJ, Yun M, Kim CK, Howrylak J, Ryter SW, Nakahira K, Choi AM.

J Clin Invest. 2015 Feb;125(2):665-80. doi: 10.1172/JCI78253. Epub 2015 Jan 9.


Maf1 is a novel target of PTEN and PI3K signaling that negatively regulates oncogenesis and lipid metabolism.

Palian BM, Rohira AD, Johnson SA, He L, Zheng N, Dubeau L, Stiles BL, Johnson DL.

PLoS Genet. 2014 Dec 11;10(12):e1004789. doi: 10.1371/journal.pgen.1004789. eCollection 2014 Dec. Erratum in: PLoS Genet. 2015 Mar;11(3):e1005055.


The selective target of capsaicin on FASN expression and de novo fatty acid synthesis mediated through ROS generation triggers apoptosis in HepG2 cells.

Impheng H, Pongcharoen S, Richert L, Pekthong D, Srisawang P.

PLoS One. 2014 Sep 25;9(9):e107842. doi: 10.1371/journal.pone.0107842. eCollection 2014.


Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells.

Corominas-Faja B, Cuyàs E, Gumuzio J, Bosch-Barrera J, Leis O, Martin ÁG, Menendez JA.

Oncotarget. 2014 Sep 30;5(18):8306-16.


Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer.

Roy D, Mondal S, Wang C, He X, Khurana A, Giri S, Hoffmann R, Jung DB, Kim SH, Chini EN, Periera JC, Folmes CD, Mariani A, Dowdy SC, Bakkum-Gamez JN, Riska SM, Oberg AL, Karoly ED, Bell LN, Chien J, Shridhar V.

Cancer Metab. 2014 Aug 18;2:13. doi: 10.1186/2049-3002-2-13. eCollection 2014. Erratum in: Cancer Metab. 2014;2:24.


Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment.

Daniëls VW, Smans K, Royaux I, Chypre M, Swinnen JV, Zaidi N.

PLoS One. 2014 Sep 12;9(9):e106913. doi: 10.1371/journal.pone.0106913. eCollection 2014.


Fatty Acid Composition of Tissue Cultured Breast Carcinoma and the Effect of Stearoyl-CoA Desaturase 1 Inhibition.

Mohammadzadeh F, Mosayebi G, Montazeri V, Darabi M, Fayezi S, Shaaker M, Rahmati M, Baradaran B, Mehdizadeh A, Darabi M.

J Breast Cancer. 2014 Jun;17(2):136-42. doi: 10.4048/jbc.2014.17.2.136. Epub 2014 Jun 27.


Glycerophosphoglycerol, Beta-alanine, and pantothenic Acid as metabolic companions of glycolytic activity and cell migration in breast cancer cell lines.

Hutschenreuther A, Birkenmeier G, Bigl M, Krohn K, Birkemeyer C.

Metabolites. 2013 Nov 27;3(4):1084-101. doi: 10.3390/metabo3041084.


Metformin: On Ongoing Journey across Diabetes, Cancer Therapy and Prevention.

Pulito C, Sanli T, Rana P, Muti P, Blandino G, Strano S.

Metabolites. 2013 Nov 7;3(4):1051-75. doi: 10.3390/metabo3041051.


Increased phosphatidylethanolamine N-methyltransferase gene expression in non-small-cell lung cancer tissue predicts shorter patient survival.

Zinrajh D, Hörl G, Jürgens G, Marc J, Sok M, Cerne D.

Oncol Lett. 2014 Jun;7(6):2175-2179. Epub 2014 Apr 4.


Lipid metabolism enzyme ACSVL3 supports glioblastoma stem cell maintenance and tumorigenicity.

Sun P, Xia S, Lal B, Shi X, Yang KS, Watkins PA, Laterra J.

BMC Cancer. 2014 Jun 4;14:401. doi: 10.1186/1471-2407-14-401.


Targeting FASN in Breast Cancer and the Discovery of Promising Inhibitors from Natural Products Derived from Traditional Chinese Medicine.

Cheng CS, Wang Z, Chen J.

Evid Based Complement Alternat Med. 2014;2014:232946. doi: 10.1155/2014/232946. Epub 2014 Mar 13. Review.


Antitumoral activity of snake venom proteins: new trends in cancer therapy.

Calderon LA, Sobrinho JC, Zaqueo KD, de Moura AA, Grabner AN, Mazzi MV, Marcussi S, Nomizo A, Fernandes CF, Zuliani JP, Carvalho BM, da Silva SL, Stábeli RG, Soares AM.

Biomed Res Int. 2014;2014:203639. doi: 10.1155/2014/203639. Epub 2014 Feb 13. Review.

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