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Items: 1 to 20 of 55

1.

Rice endosperm is cost-effective for the production of recombinant griffithsin with potent activity against HIV.

Vamvaka E, Arcalis E, Ramessar K, Evans A, O'Keefe BR, Shattock RJ, Medina V, Stöger E, Christou P, Capell T.

Plant Biotechnol J. 2016 Jun;14(6):1427-37. doi: 10.1111/pbi.12507. Epub 2016 Jan 23.

2.

Animal and human mucosal tissue models to study HIV biomedical interventions: can we predict success?

Dezzutti CS.

J Int AIDS Soc. 2015 Nov 2;18:20301. doi: 10.7448/IAS.18.1.20301. eCollection 2015. Review.

3.

Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus.

Levendosky K, Mizenina O, Martinelli E, Jean-Pierre N, Kizima L, Rodriguez A, Kleinbeck K, Bonnaire T, Robbiani M, Zydowsky TM, O'Keefe BR, Fernández-Romero JA.

Antimicrob Agents Chemother. 2015 Dec;59(12):7290-8. doi: 10.1128/AAC.01816-15. Epub 2015 Sep 14.

4.

Anti-Retroviral Lectins Have Modest Effects on Adherence of Trichomonas vaginalis to Epithelial Cells In Vitro and on Recovery of Tritrichomonas foetus in a Mouse Vaginal Model.

Chatterjee A, Ratner DM, Ryan CM, Johnson PJ, O'Keefe BR, Secor WE, Anderson DJ, Robbins PW, Samuelson J.

PLoS One. 2015 Aug 7;10(8):e0135340. doi: 10.1371/journal.pone.0135340. eCollection 2015.

5.

Improving the large scale purification of the HIV microbicide, griffithsin.

Fuqua JL, Wanga V, Palmer KE.

BMC Biotechnol. 2015 Feb 22;15:12. doi: 10.1186/s12896-015-0120-5.

6.

Multipurpose prevention technologies: the future of HIV and STI protection.

Fernández-Romero JA, Deal C, Herold BC, Schiller J, Patton D, Zydowsky T, Romano J, Petro CD, Narasimhan M.

Trends Microbiol. 2015 Jul;23(7):429-36. doi: 10.1016/j.tim.2015.02.006. Epub 2015 Mar 7. Review.

7.

Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus.

Moulaei T, Alexandre KB, Shenoy SR, Meyerson JR, Krumpe LR, Constantine B, Wilson J, Buckheit RW Jr, McMahon JB, Subramaniam S, Wlodawer A, O'Keefe BR.

Retrovirology. 2015 Jan 23;12:6. doi: 10.1186/s12977-014-0127-3.

8.

Engineering soya bean seeds as a scalable platform to produce cyanovirin-N, a non-ARV microbicide against HIV.

O'Keefe BR, Murad AM, Vianna GR, Ramessar K, Saucedo CJ, Wilson J, Buckheit KW, da Cunha NB, Araújo AC, Lacorte CC, Madeira L, McMahon JB, Rech EL.

Plant Biotechnol J. 2015 Sep;13(7):884-92. doi: 10.1111/pbi.12309. Epub 2015 Jan 9.

9.

A modular cloning toolbox for the generation of chloroplast transformation vectors.

Vafaee Y, Staniek A, Mancheno-Solano M, Warzecha H.

PLoS One. 2014 Oct 10;9(10):e110222. doi: 10.1371/journal.pone.0110222. eCollection 2014.

10.

The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus.

Garrison AR, Giomarelli BG, Lear-Rooney CM, Saucedo CJ, Yellayi S, Krumpe LR, Rose M, Paragas J, Bray M, Olinger GG Jr, McMahon JB, Huggins J, O'Keefe BR.

Antiviral Res. 2014 Dec;112:1-7. doi: 10.1016/j.antiviral.2014.09.012. Epub 2014 Oct 5.

11.

Antiviral lectins as potential HIV microbicides.

Koharudin LM, Gronenborn AM.

Curr Opin Virol. 2014 Aug;7:95-100. doi: 10.1016/j.coviro.2014.05.006. Epub 2014 Jul 8. Review.

12.

Broad anti-HIV activity of the Oscillatoria agardhii agglutinin homologue lectin family.

Férir G, Huskens D, Noppen S, Koharudin LM, Gronenborn AM, Schols D.

J Antimicrob Chemother. 2014 Oct;69(10):2746-58. doi: 10.1093/jac/dku220. Epub 2014 Jun 25.

13.

Differential inhibitory effects of cyanovirin-N, griffithsin, and scytovirin on entry mediated by envelopes of gammaretroviruses and deltaretroviruses.

Jensen SM, Ruscetti FW, Rein A, Bertolette DC, Saucedo CJ, O'Keefe BR, Jones KS.

J Virol. 2014 Feb;88(4):2327-32. doi: 10.1128/JVI.02553-13. Epub 2013 Nov 27.

14.

Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models.

Barton C, Kouokam JC, Lasnik AB, Foreman O, Cambon A, Brock G, Montefiori DC, Vojdani F, McCormick AA, O'Keefe BR, Palmer KE.

Antimicrob Agents Chemother. 2014;58(1):120-7. doi: 10.1128/AAC.01407-13. Epub 2013 Oct 21.

15.

Mechanisms of HIV-1 subtype C resistance to GRFT, CV-N and SVN.

Alexandre KB, Moore PL, Nonyane M, Gray ES, Ranchobe N, Chakauya E, McMahon JB, O'Keefe BR, Chikwamba R, Morris L.

Virology. 2013 Nov;446(1-2):66-76. doi: 10.1016/j.virol.2013.07.019. Epub 2013 Aug 15.

16.

Development of an HIV-1 Microbicide Based on Caulobacter crescentus: Blocking Infection by High-Density Display of Virus Entry Inhibitors.

Farr C, Nomellini JF, Ailon E, Shanina I, Sangsari S, Cavacini LA, Smit J, Horwitz MS.

PLoS One. 2013 Jun 19;8(6):e65965. doi: 10.1371/journal.pone.0065965. Print 2013.

17.

A modified zinc acetate gel, a potential nonantiretroviral microbicide, is safe and effective against simian-human immunodeficiency virus and herpes simplex virus 2 infection in vivo.

Kenney J, Rodríguez A, Kizima L, Seidor S, Menon R, Jean-Pierre N, Pugach P, Levendosky K, Derby N, Gettie A, Blanchard J, Piatak M Jr, Lifson JD, Paglini G, Zydowsky TM, Robbiani M, Fernández Romero JA.

Antimicrob Agents Chemother. 2013 Aug;57(8):4001-9. doi: 10.1128/AAC.00796-13. Epub 2013 Jun 10.

18.

The griffithsin dimer is required for high-potency inhibition of HIV-1: evidence for manipulation of the structure of gp120 as part of the griffithsin dimer mechanism.

Xue J, Hoorelbeke B, Kagiampakis I, Demeler B, Balzarini J, Liwang PJ.

Antimicrob Agents Chemother. 2013 Aug;57(8):3976-89. doi: 10.1128/AAC.00332-13. Epub 2013 Jun 10.

19.

Role of the carbohydrate-binding sites of griffithsin in the prevention of DC-SIGN-mediated capture and transmission of HIV-1.

Hoorelbeke B, Xue J, LiWang PJ, Balzarini J.

PLoS One. 2013 May 31;8(5):e64132. doi: 10.1371/journal.pone.0064132. Print 2013.

20.

Antiviral lectins from red and blue-green algae show potent in vitro and in vivo activity against hepatitis C virus.

Takebe Y, Saucedo CJ, Lund G, Uenishi R, Hase S, Tsuchiura T, Kneteman N, Ramessar K, Tyrrell DL, Shirakura M, Wakita T, McMahon JB, O'Keefe BR.

PLoS One. 2013 May 21;8(5):e64449. doi: 10.1371/journal.pone.0064449. Print 2013.

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