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Impact of Cocoa Consumption on Inflammation Processes-A Critical Review of Randomized Controlled Trials.

Ellinger S, Stehle P.

Nutrients. 2016 May 26;8(6). pii: E321. doi: 10.3390/nu8060321. Review.


Theobroma cacao: Review of the Extraction, Isolation, and Bioassay of Its Potential Anti-cancer Compounds.

Baharum Z, Akim AM, Hin TY, Hamid RA, Kasran R.

Trop Life Sci Res. 2016 Feb;27(1):21-42.


Dietary Cocoa Powder Improves Hyperlipidemia and Reduces Atherosclerosis in apoE Deficient Mice through the Inhibition of Hepatic Endoplasmic Reticulum Stress.

Guan H, Lin Y, Bai L, An Y, Shang J, Wang Z, Zhao S, Fan J, Liu E.

Mediators Inflamm. 2016;2016:1937572. doi: 10.1155/2016/1937572. Epub 2016 Feb 15.


Epigenetic associations in relation to cardiovascular prevention and therapeutics.

Voelter-Mahlknecht S.

Clin Epigenetics. 2016 Jan 15;8:4. doi: 10.1186/s13148-016-0170-0. eCollection 2016. Review.


Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review.

Mozaffarian D.

Circulation. 2016 Jan 12;133(2):187-225. doi: 10.1161/CIRCULATIONAHA.115.018585.


Dark chocolate supplementation reduces the oxygen cost of moderate intensity cycling.

Patel RK, Brouner J, Spendiff O.

J Int Soc Sports Nutr. 2015 Dec 15;12:47. doi: 10.1186/s12970-015-0106-7. eCollection 2015.


Total Phenolic Content and Antioxidant Activity of Different Types of Chocolate, Milk, Semisweet, Dark, and Soy, in Cerebral Cortex, Hippocampus, and Cerebellum of Wistar Rats.

da Silva Medeiros N, Koslowsky Marder R, Farias Wohlenberg M, Funchal C, Dani C.

Biochem Res Int. 2015;2015:294659. doi: 10.1155/2015/294659. Epub 2015 Nov 16.


Molecular Mechanisms and Therapeutic Effects of (-)-Epicatechin and Other Polyphenols in Cancer, Inflammation, Diabetes, and Neurodegeneration.

Shay J, Elbaz HA, Lee I, Zielske SP, Malek MH, Hüttemann M.

Oxid Med Cell Longev. 2015;2015:181260. doi: 10.1155/2015/181260. Epub 2015 Jun 9. Review.


The acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: a randomized, controlled trial.

Massee LA, Ried K, Pase M, Travica N, Yoganathan J, Scholey A, Macpherson H, Kennedy G, Sali A, Pipingas A.

Front Pharmacol. 2015 May 20;6:93. doi: 10.3389/fphar.2015.00093. eCollection 2015.


Chocolate-candy consumption and 3-year weight gain among postmenopausal U.S. women.

Greenberg JA, Manson JE, Buijsse B, Wang L, Allison MA, Neuhouser ML, Tinker L, Waring ME, Isasi CR, Martin LW, Thomson CA.

Obesity (Silver Spring). 2015 Mar;23(3):677-83. doi: 10.1002/oby.20983. Epub 2015 Feb 3.


Deleterious effects of maternal ingestion of cocoa upon fetal ductus arteriosus in late pregnancy.

Zielinsky P, Martignoni FV, Vian I.

Front Pharmacol. 2014 Dec 22;5:281. doi: 10.3389/fphar.2014.00281. eCollection 2014.


Changes in body weight, blood pressure and selected metabolic biomarkers with an energy-restricted diet including twice daily sweet snacks and once daily sugar-free beverage.

Nickols-Richardson SM, Piehowski KE, Metzgar CJ, Miller DL, Preston AG.

Nutr Res Pract. 2014 Dec;8(6):695-704. doi: 10.4162/nrp.2014.8.6.695. Epub 2014 Nov 5.


Short term effects of cocoa consumption on blood pressure.

Alleyne T, Alleyne A, Arrindell D, Balleram N, Cozier D, Haywood R, Humphrey C, Pran L, Rampersad K, Reyes D, Bahall S, Holder R, Ignacio D.

West Indian Med J. 2014 Aug;63(4):312-7. doi: 10.7727/wimj.2013.273. Epub 2013 Dec 2.


Cocoa bioactive compounds: significance and potential for the maintenance of skin health.

Scapagnini G, Davinelli S, Di Renzo L, De Lorenzo A, Olarte HH, Micali G, Cicero AF, Gonzalez S.

Nutrients. 2014 Aug 11;6(8):3202-13. doi: 10.3390/nu6083202. Review.


Dark chocolate acutely improves walking autonomy in patients with peripheral artery disease.

Loffredo L, Perri L, Catasca E, Pignatelli P, Brancorsini M, Nocella C, De Falco E, Bartimoccia S, Frati G, Carnevale R, Violi F.

J Am Heart Assoc. 2014 Jul 2;3(4). pii: e001072. doi: 10.1161/JAHA.114.001072. Erratum in: J Am Heart Assoc. 2014 Aug;3(4):e000456.


Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function.

Yamazaki KG, Andreyev AY, Ortiz-Vilchis P, Petrosyan S, Divakaruni AS, Wiley SE, De La Fuente C, Perkins G, Ceballos G, Villarreal F, Murphy AN.

Int J Cardiol. 2014 Aug 1;175(2):297-306. doi: 10.1016/j.ijcard.2014.05.009. Epub 2014 May 15.


Cell membrane mediated (-)-epicatechin effects on upstream endothelial cell signaling: evidence for a surface receptor.

Moreno-Ulloa A, Romero-Perez D, Villarreal F, Ceballos G, Ramirez-Sanchez I.

Bioorg Med Chem Lett. 2014 Jun 15;24(12):2749-52. doi: 10.1016/j.bmcl.2014.04.038. Epub 2014 Apr 19.


Cocoa polyphenols and inflammatory markers of cardiovascular disease.

Khan N, Khymenets O, Urpí-Sardà M, Tulipani S, Garcia-Aloy M, Monagas M, Mora-Cubillos X, Llorach R, Andres-Lacueva C.

Nutrients. 2014 Feb 21;6(2):844-80. doi: 10.3390/nu6020844. Review.


Dietary cocoa reduces metabolic endotoxemia and adipose tissue inflammation in high-fat fed mice.

Gu Y, Yu S, Park JY, Harvatine K, Lambert JD.

J Nutr Biochem. 2014 Apr;25(4):439-45. doi: 10.1016/j.jnutbio.2013.12.004. Epub 2013 Dec 31.


Immunomodulatory properties of cacao extracts - potential consequences for medical applications.

Becker K, Geisler S, Ueberall F, Fuchs D, Gostner JM.

Front Pharmacol. 2013 Dec 12;4:154. doi: 10.3389/fphar.2013.00154. Review.

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