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Items: 11


The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD.

Sun J, Siroy A, Lokareddy RK, Speer A, Doornbos KS, Cingolani G, Niederweis M.

Nat Struct Mol Biol. 2015 Sep;22(9):672-8. doi: 10.1038/nsmb.3064. Epub 2015 Aug 3.


An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity.

Danilchanka O, Sun J, Pavlenok M, Maueröder C, Speer A, Siroy A, Marrero J, Trujillo C, Mayhew DL, Doornbos KS, Muñoz LE, Herrmann M, Ehrt S, Berens C, Niederweis M.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6750-5. doi: 10.1073/pnas.1400136111. Epub 2014 Apr 21.


Big brains, meat, tuberculosis, and the nicotinamide switches: co-evolutionary relationships with modern repercussions?

Williams AC, Dunbar RI.

Int J Tryptophan Res. 2013 Oct 15;6:73-88. doi: 10.4137/IJTR.S12838. eCollection 2013.


Distributive conjugal transfer in mycobacteria generates progeny with meiotic-like genome-wide mosaicism, allowing mapping of a mating identity locus.

Gray TA, Krywy JA, Harold J, Palumbo MJ, Derbyshire KM.

PLoS Biol. 2013 Jul;11(7):e1001602. doi: 10.1371/journal.pbio.1001602. Epub 2013 Jul 9.


Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis.

Supply P, Marceau M, Mangenot S, Roche D, Rouanet C, Khanna V, Majlessi L, Criscuolo A, Tap J, Pawlik A, Fiette L, Orgeur M, Fabre M, Parmentier C, Frigui W, Simeone R, Boritsch EC, Debrie AS, Willery E, Walker D, Quail MA, Ma L, Bouchier C, Salvignol G, Sayes F, Cascioferro A, Seemann T, Barbe V, Locht C, Gutierrez MC, Leclerc C, Bentley SD, Stinear TP, Brisse S, Médigue C, Parkhill J, Cruveiller S, Brosch R.

Nat Genet. 2013 Feb;45(2):172-9. doi: 10.1038/ng.2517. Epub 2013 Jan 6.


Mycobacterium tuberculosis complex lipid virulence factors preserved in the 17,000-year-old skeleton of an extinct bison, Bison antiquus.

Lee OY, Wu HH, Donoghue HD, Spigelman M, Greenblatt CL, Bull ID, Rothschild BM, Martin LD, Minnikin DE, Besra GS.

PLoS One. 2012;7(7):e41923. doi: 10.1371/journal.pone.0041923. Epub 2012 Jul 30.


Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death.

Simeone R, Bobard A, Lippmann J, Bitter W, Majlessi L, Brosch R, Enninga J.

PLoS Pathog. 2012 Feb;8(2):e1002507. doi: 10.1371/journal.ppat.1002507. Epub 2012 Feb 2.


Comparative transcriptional study of the putative mannose donor biosynthesis genes in virulent Mycobacterium tuberculosis and attenuated Mycobacterium bovis BCG strains.

Keiser TL, Azad AK, Guirado E, Bonacci R, Schlesinger LS.

Infect Immun. 2011 Nov;79(11):4668-73. doi: 10.1128/IAI.05635-11. Epub 2011 Sep 6.


Novel Mycobacterium tuberculosis complex pathogen, M. mungi.

Alexander KA, Laver PN, Michel AL, Williams M, van Helden PD, Warren RM, Gey van Pittius NC.

Emerg Infect Dis. 2010 Aug;16(8):1296-9. doi: 10.3201/eid1608.100314. Erratum in: Emerg Infect Dis. 2010 Dec;16(12):2024.


Using a label-free proteomics method to identify differentially abundant proteins in closely related hypo- and hypervirulent clinical Mycobacterium tuberculosis Beijing isolates.

de Souza GA, Fortuin S, Aguilar D, Pando RH, McEvoy CR, van Helden PD, Koehler CJ, Thiede B, Warren RM, Wiker HG.

Mol Cell Proteomics. 2010 Nov;9(11):2414-23. doi: 10.1074/mcp.M900422-MCP200. Epub 2010 Feb 26.


Strains of the East Asian (W/Beijing) lineage of Mycobacterium tuberculosis are DosS/DosT-DosR two-component regulatory system natural mutants.

Fallow A, Domenech P, Reed MB.

J Bacteriol. 2010 Apr;192(8):2228-38. doi: 10.1128/JB.01597-09. Epub 2010 Feb 12.

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