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Items: 1 to 20 of 183


Vibration exercise decreases insulin resistance and modulates the insulin signaling pathway in a type 2 diabetic rat model.

Liu Y, Liu C, Lu ML, Tang FT, Hou XW, Yang J, Liu T.

Int J Clin Exp Med. 2015 Aug 15;8(8):13136-44. eCollection 2015.


The associations between Parkinson's disease and cancer: the plot thickens.

Feng DD, Cai W, Chen X.

Transl Neurodegener. 2015 Oct 26;4:20. doi: 10.1186/s40035-015-0043-z. eCollection 2015. Review.


Differentiating the mTOR inhibitors everolimus and sirolimus in the treatment of tuberous sclerosis complex.

MacKeigan JP, Krueger DA.

Neuro Oncol. 2015 Dec;17(12):1550-9. doi: 10.1093/neuonc/nov152. Epub 2015 Aug 19. Review.


Cyclin G Functions as a Positive Regulator of Growth and Metabolism in Drosophila.

Fischer P, La Rosa MK, Schulz A, Preiss A, Nagel AC.

PLoS Genet. 2015 Aug 14;11(8):e1005440. doi: 10.1371/journal.pgen.1005440. eCollection 2015 Aug.


Point mutations of the mTOR-RHEB pathway in renal cell carcinoma.

Ghosh AP, Marshall CB, Coric T, Shim EH, Kirkman R, Ballestas ME, Ikura M, Bjornsti MA, Sudarshan S.

Oncotarget. 2015 Jul 20;6(20):17895-910.


Milk--A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent Translation.

Melnik BC.

Int J Mol Sci. 2015 Jul 27;16(8):17048-87. doi: 10.3390/ijms160817048. Review.


Polybrominated diphenyl ether congener, BDE-47, impairs insulin sensitivity in mice with liver-specific Pten deficiency.

McIntyre RL, Kenerson HL, Subramanian S, Wang SA, Kazami M, Stapleton HM, Yeung RS.

BMC Obes. 2015 Feb 7;2:3. doi: 10.1186/s40608-014-0031-3. eCollection 2015.


Active mechanistic target of rapamycin plays an ancillary rather than essential role in zebrafish CNS axon regeneration.

Diekmann H, Kalbhen P, Fischer D.

Front Cell Neurosci. 2015 Jul 7;9:251. doi: 10.3389/fncel.2015.00251. eCollection 2015.


Rapamycin reverses paraquat-induced acute lung injury in a rat model through inhibition of NFκB activation.

Chen D, Ma T, Liu XW, Yang C, Liu Z.

Int J Clin Exp Pathol. 2015 May 1;8(5):4627-38. eCollection 2015.


Glucose transporter 3 performs a critical role in mTOR-mediated oncogenic glycolysis and tumorigenesis.

Zhang Y, Wei C, Xi J, Tang Z, Liang C.

Oncol Lett. 2015 Jun;9(6):2809-2814. Epub 2015 Mar 26.


p70S6K is regulated by focal adhesion kinase and is required for Src-selective autophagy.

Sandilands E, Schoenherr C, Frame MC.

Cell Signal. 2015 Sep;27(9):1816-23. doi: 10.1016/j.cellsig.2015.05.017. Epub 2015 Jun 9.


The mitochondrial uncoupler DNP triggers brain cell mTOR signaling network reprogramming and CREB pathway up-regulation.

Liu D, Zhang Y, Gharavi R, Park HR, Lee J, Siddiqui S, Telljohann R, Nassar MR, Cutler RG, Becker KG, Mattson MP.

J Neurochem. 2015 Aug;134(4):677-92. doi: 10.1111/jnc.13176. Epub 2015 Jun 19.


Clinical features, epidemiology, and therapy of lymphangioleiomyomatosis.

Taveira-DaSilva AM, Moss J.

Clin Epidemiol. 2015 Apr 7;7:249-57. doi: 10.2147/CLEP.S50780. eCollection 2015. Review.


17ß-Estradiol regulates mTORC2 sensitivity to rapamycin in adaptive cardiac remodeling.

Kusch A, Schmidt M, Gürgen D, Postpieszala D, Catar R, Hegner B, Davidson MM, Mahmoodzadeh S, Dragun D.

PLoS One. 2015 Apr 16;10(4):e0123385. doi: 10.1371/journal.pone.0123385. eCollection 2015.


The impact of host diet on Wolbachia titer in Drosophila.

Serbus LR, White PM, Silva JP, Rabe A, Teixeira L, Albertson R, Sullivan W.

PLoS Pathog. 2015 Mar 31;11(3):e1004777. doi: 10.1371/journal.ppat.1004777. eCollection 2015 Mar. Erratum in: PLoS Pathog. 2015 May;11(5):e1004889.


Livers with constitutive mTORC1 activity resist steatosis independent of feedback suppression of Akt.

Kenerson HL, Subramanian S, McIntyre R, Kazami M, Yeung RS.

PLoS One. 2015 Feb 3;10(2):e0117000. doi: 10.1371/journal.pone.0117000. eCollection 2015.


Signalling mechanisms regulating phenotypic changes in breast cancer cells.

Volinsky N, McCarthy CJ, von Kriegsheim A, Saban N, Okada-Hatakeyama M, Kolch W, Kholodenko BN.

Biosci Rep. 2015 Mar 18;35(2). pii: e00178. doi: 10.1042/BSR20140172.


Reciprocal regulation of AMP-activated protein kinase and phospholipase D.

Mukhopadhyay S, Saqcena M, Chatterjee A, Garcia A, Frias MA, Foster DA.

J Biol Chem. 2015 Mar 13;290(11):6986-93. doi: 10.1074/jbc.M114.622571. Epub 2015 Jan 29.


Management of lymphangioleiomyomatosis.

Taveira-DaSilva AM, Moss J.

F1000Prime Rep. 2014 Dec 1;6:116. doi: 10.12703/P6-116. eCollection 2014. Review.


A vascular model of Tsc1 deficiency accelerates renal tumor formation with accompanying hemangiosarcomas.

Leech JD, Lammers SH, Goldman S, Auricchio N, Bronson RT, Kwiatkowski DJ, Sahin M.

Mol Cancer Res. 2015 Mar;13(3):548-55. doi: 10.1158/1541-7786.MCR-14-0178. Epub 2014 Dec 29.

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