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Results: 1 to 20 of 33

Cited In for PubMed (Select 19017562)


Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention.

Carman A, Kishinevsky S, Koren J 3rd, Lou W, Chiosis G.

J Alzheimers Dis Parkinsonism. 2013 Apr;2013(Suppl 10). pii: 007.


Hsp90 inhibitors as new leads to target parasitic diarrheal diseases.

Debnath A, Shahinas D, Bryant C, Hirata K, Miyamoto Y, Hwang G, Gut J, Renslo AR, Pillai DR, Eckmann L, Reed SL, McKerrow JH.

Antimicrob Agents Chemother. 2014 Jul;58(7):4138-44. doi: 10.1128/AAC.02576-14. Epub 2014 May 12.


Protein chaperones: a composition of matter review (2008 - 2013).

Taldone T, Patel HJ, Bolaender A, Patel MR, Chiosis G.

Expert Opin Ther Pat. 2014 May;24(5):501-18. doi: 10.1517/13543776.2014.887681. Review.


A repurposing strategy for Hsp90 inhibitors demonstrates their potency against filarial nematodes.

Gillan V, O'Neill K, Maitland K, Sverdrup FM, Devaney E.

PLoS Negl Trop Dis. 2014 Feb 13;8(2):e2699. doi: 10.1371/journal.pntd.0002699. eCollection 2014 Feb.


Small-molecule control of intracellular protein levels through modulation of the ubiquitin proteasome system.

Buckley DL, Crews CM.

Angew Chem Int Ed Engl. 2014 Feb 24;53(9):2312-30. doi: 10.1002/anie.201307761. Epub 2014 Jan 23. Review.


Network analysis identifies an HSP90-central hub susceptible in ovarian cancer.

Liu H, Xiao F, Serebriiskii IG, O'Brien SW, Maglaty MA, Astsaturov I, Litwin S, Martin LP, Proia DA, Golemis EA, Connolly DC.

Clin Cancer Res. 2013 Sep 15;19(18):5053-67. doi: 10.1158/1078-0432.CCR-13-1115. Epub 2013 Jul 30.


Targeting heat shock protein 90 for the treatment of malignant pheochromocytoma.

Giubellino A, Sourbier C, Lee MJ, Scroggins B, Bullova P, Landau M, Ying W, Neckers L, Trepel JB, Pacak K.

PLoS One. 2013;8(2):e56083. doi: 10.1371/journal.pone.0056083. Epub 2013 Feb 14.


Diabetic peripheral neuropathy: should a chaperone accompany our therapeutic approach?

Farmer KL, Li C, Dobrowsky RT.

Pharmacol Rev. 2012 Oct;64(4):880-900. doi: 10.1124/pr.111.005314. Epub 2012 Aug 10. Review.


Thermodynamics of aryl-dihydroxyphenyl-thiadiazole binding to human Hsp90.

Kazlauskas E, Petrikaitė V, Michailovienė V, Revuckienė J, Matulienė J, Grinius L, Matulis D.

PLoS One. 2012;7(5):e36899. doi: 10.1371/journal.pone.0036899. Epub 2012 May 24. Erratum in: PLoS One. 2012;7(6). doi:10.1371/annotation/fb1b3941-789b-4d6f-8463-19a877124f78.


Synthesis and evaluation of 11β-(4-substituted phenyl) estradiol analogs: transition from estrogen receptor agonists to antagonists.

Hanson RN, Hua E, Hendricks JA, Labaree D, Hochberg RB.

Bioorg Med Chem. 2012 Jun 15;20(12):3768-80. doi: 10.1016/j.bmc.2012.04.041. Epub 2012 May 7.


Advances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment.

Patel HJ, Modi S, Chiosis G, Taldone T.

Expert Opin Drug Discov. 2011 May;6(5):559-587.


Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers.

Jhaveri K, Taldone T, Modi S, Chiosis G.

Biochim Biophys Acta. 2012 Mar;1823(3):742-55. doi: 10.1016/j.bbamcr.2011.10.008. Epub 2011 Oct 29. Review.


HSP90 functions in the circadian clock through stabilization of the client F-box protein ZEITLUPE.

Kim TS, Kim WY, Fujiwara S, Kim J, Cha JY, Park JH, Lee SY, Somers DE.

Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16843-8. doi: 10.1073/pnas.1110406108. Epub 2011 Sep 26.


Molecular chaperones and regulation of tau quality control: strategies for drug discovery in tauopathies.

Miyata Y, Koren J, Kiray J, Dickey CA, Gestwicki JE.

Future Med Chem. 2011 Sep;3(12):1523-37. doi: 10.4155/fmc.11.88. Review.


Regulated binding of importin-α to protein kinase Cδ in response to apoptotic signals facilitates nuclear import.

Adwan TS, Ohm AM, Jones DN, Humphries MJ, Reyland ME.

J Biol Chem. 2011 Oct 14;286(41):35716-24. doi: 10.1074/jbc.M111.255950. Epub 2011 Aug 24.


Design, synthesis, and evaluation of small molecule Hsp90 probes.

Taldone T, Zatorska D, Patel PD, Zong H, Rodina A, Ahn JH, Moulick K, Guzman ML, Chiosis G.

Bioorg Med Chem. 2011 Apr 15;19(8):2603-14. doi: 10.1016/j.bmc.2011.03.013. Epub 2011 Mar 12. Review.


Enforced N-domain proximity stimulates Hsp90 ATPase activity and is compatible with function in vivo.

Pullen L, Bolon DN.

J Biol Chem. 2011 Apr 1;286(13):11091-8. doi: 10.1074/jbc.M111.223131. Epub 2011 Jan 28.


Molecular chaperones as rational drug targets for Parkinson's disease therapeutics.

Kalia SK, Kalia LV, McLean PJ.

CNS Neurol Disord Drug Targets. 2010 Dec;9(6):741-53. Review.


Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2009.

Dolle RE, Bourdonnec BL, Worm K, Morales GA, Thomas CJ, Zhang W.

J Comb Chem. 2010 Nov 8;12(6):765-806. doi: 10.1021/cc100128w. Epub 2010 Oct 5. Review. No abstract available.

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