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Differential expression of P2X7 receptor and IL-1β in nociceptive and neuropathic pain.

Luchting B, Heyn J, Woehrle T, Rachinger-Adam B, Kreth S, Hinske LC, Azad SC.

J Neuroinflammation. 2016 May 4;13(1):100. doi: 10.1186/s12974-016-0565-z.


Paroxetine suppresses recombinant human P2X7 responses.

Dao-Ung P, Skarratt KK, Fuller SJ, Stokes L.

Purinergic Signal. 2015 Dec;11(4):481-90. doi: 10.1007/s11302-015-9467-2. Epub 2015 Sep 5.


Understanding the role of P2X7 in affective disorders-are glial cells the major players?

Stokes L, Spencer SJ, Jenkins TA.

Front Cell Neurosci. 2015 Jul 8;9:258. doi: 10.3389/fncel.2015.00258. eCollection 2015. Review.


Study on the behavioral changes of a post-stroke depression rat model.

Wu C, Zhang J, Chen Y.

Exp Ther Med. 2015 Jul;10(1):159-163. Epub 2015 Apr 24.


ATP as a multi-target danger signal in the brain.

Rodrigues RJ, Tomé AR, Cunha RA.

Front Neurosci. 2015 Apr 28;9:148. doi: 10.3389/fnins.2015.00148. eCollection 2015. Review.


P2X and P2Y receptors—role in the pathophysiology of the nervous system.

Puchałowicz K, Tarnowski M, Baranowska-Bosiacka I, Chlubek D, Dziedziejko V.

Int J Mol Sci. 2014 Dec 18;15(12):23672-704. doi: 10.3390/ijms151223672. Review.


Purinergic system dysfunction in mood disorders: a key target for developing improved therapeutics.

Ortiz R, Ulrich H, Zarate CA Jr, Machado-Vieira R.

Prog Neuropsychopharmacol Biol Psychiatry. 2015 Mar 3;57:117-31. doi: 10.1016/j.pnpbp.2014.10.016. Epub 2014 Nov 7. Review.


Effects of Brilliant Blue G on Serum Tumor Necrosis Factor-α Levels and Depression-like Behavior in Mice after Lipopolysaccharide Administration.

Ma M, Ren Q, Zhang JC, Hashimoto K.

Clin Psychopharmacol Neurosci. 2014 Apr;12(1):31-6. doi: 10.9758/cpn.2014.12.1.31. Epub 2014 Apr 24.


The first CNS-active carborane: A novel P2X7 receptor antagonist with antidepressant activity.

Wilkinson SM, Gunosewoyo H, Barron ML, Boucher A, McDonnell M, Turner P, Morrison DE, Bennett MR, McGregor IS, Rendina LM, Kassiou M.

ACS Chem Neurosci. 2014 May 21;5(5):335-9. doi: 10.1021/cn500054n. Epub 2014 Apr 3. Review.


Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice.

Beaucage KL, Xiao A, Pollmann SI, Grol MW, Beach RJ, Holdsworth DW, Sims SM, Darling MR, Dixon SJ.

Purinergic Signal. 2014;10(2):291-304. doi: 10.1007/s11302-013-9388-x. Epub 2013 Nov 13.


Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567.

Bhattacharya A, Wang Q, Ao H, Shoblock JR, Lord B, Aluisio L, Fraser I, Nepomuceno D, Neff RA, Welty N, Lovenberg TW, Bonaventure P, Wickenden AD, Letavic MA.

Br J Pharmacol. 2013 Oct;170(3):624-40. doi: 10.1111/bph.12314.


Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors.

Csölle C, Baranyi M, Zsilla G, Kittel A, Gölöncsér F, Illes P, Papp E, Vizi ES, Sperlágh B.

PLoS One. 2013 Jun 21;8(6):e66547. doi: 10.1371/journal.pone.0066547. Print 2013.


The inflammasome: pathways linking psychological stress, depression, and systemic illnesses.

Iwata M, Ota KT, Duman RS.

Brain Behav Immun. 2013 Jul;31:105-14. doi: 10.1016/j.bbi.2012.12.008. Epub 2012 Dec 20. Review.


Activation of P2X7 promotes cerebral edema and neurological injury after traumatic brain injury in mice.

Kimbler DE, Shields J, Yanasak N, Vender JR, Dhandapani KM.

PLoS One. 2012;7(7):e41229. doi: 10.1371/journal.pone.0041229. Epub 2012 Jul 17.


Molecular and functional properties of P2X receptors--recent progress and persisting challenges.

Kaczmarek-Hájek K, Lörinczi E, Hausmann R, Nicke A.

Purinergic Signal. 2012 Sep;8(3):375-417. doi: 10.1007/s11302-012-9314-7. Epub 2012 May 1. Review.


The absence of P2X7 receptors (P2rx7) on non-haematopoietic cells leads to selective alteration in mood-related behaviour with dysregulated gene expression and stress reactivity in mice.

Csölle C, Andó RD, Kittel Á, Gölöncsér F, Baranyi M, Soproni K, Zelena D, Haller J, Németh T, Mócsai A, Sperlágh B.

Int J Neuropsychopharmacol. 2013 Feb;16(1):213-33. doi: 10.1017/S1461145711001933. Epub 2012 Jan 16.


Electroconvulsive therapy: a novel hypothesis for the involvement of purinergic signalling.

Sadek AR, Knight GE, Burnstock G.

Purinergic Signal. 2011 Dec;7(4):447-52. doi: 10.1007/s11302-011-9242-y. Epub 2011 Jun 22.


The role of P2X7 purinergic receptors in inflammatory and nociceptive changes accompanying cyclophosphamide-induced haemorrhagic cystitis in mice.

Martins JP, Silva RB, Coutinho-Silva R, Takiya CM, Battastini AM, Morrone FB, Campos MM.

Br J Pharmacol. 2012 Jan;165(1):183-96. doi: 10.1111/j.1476-5381.2011.01535.x.


Transcriptional control mechanisms associated with the nucleotide receptor P2X7, a critical regulator of immunologic, osteogenic, and neurologic functions.

Lenertz LY, Gavala ML, Zhu Y, Bertics PJ.

Immunol Res. 2011 May;50(1):22-38. doi: 10.1007/s12026-011-8203-4. Review.


Implication of the purinergic system in alcohol use disorders.

Asatryan L, Nam HW, Lee MR, Thakkar MM, Saeed Dar M, Davies DL, Choi DS.

Alcohol Clin Exp Res. 2011 Apr;35(4):584-94. doi: 10.1111/j.1530-0277.2010.01379.x. Epub 2011 Jan 11. Review.

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