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Results: 1 to 20 of 33

1.

Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1.

Sun XX, Dai MS.

World J Biol Chem. 2014 May 26;5(2):75-84. doi: 10.4331/wjbc.v5.i2.75. Review.

PMID:
24920999
[PubMed]
Free PMC Article
2.

Distinct phylogenetic relationships and biochemical properties of Arabidopsis ovarian tumor-related deubiquitinases support their functional differentiation.

Radjacommare R, Usharani R, Kuo CH, Fu H.

Front Plant Sci. 2014 Mar 12;5:84. doi: 10.3389/fpls.2014.00084. eCollection 2014.

PMID:
24659992
[PubMed]
Free PMC Article
3.

The Role of Ubiquitination in TWEAK-Stimulated Signaling.

Vucic D.

Front Immunol. 2013 Dec 19;4:472. doi: 10.3389/fimmu.2013.00472.

PMID:
24391645
[PubMed]
Free PMC Article
4.

Deubiquitinating enzyme specificity for ubiquitin chain topology profiled by di-ubiquitin activity probes.

McGouran JF, Gaertner SR, Altun M, Kramer HB, Kessler BM.

Chem Biol. 2013 Dec 19;20(12):1447-55. doi: 10.1016/j.chembiol.2013.10.012. Epub 2013 Nov 27.

PMID:
24290882
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

OTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3.

Herhaus L, Al-Salihi M, Macartney T, Weidlich S, Sapkota GP.

Nat Commun. 2013;4:2519. doi: 10.1038/ncomms3519.

PMID:
24071738
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Modifying the vicinity of the isopeptide bond to reveal differential behavior of ubiquitin chains with interacting proteins: organic chemistry applied to synthetic proteins.

Haj-Yahya N, Haj-Yahya M, Castañeda CA, Spasser L, Hemantha HP, Jbara M, Penner M, Ciechanover A, Fushman D, Brik A.

Angew Chem Int Ed Engl. 2013 Oct 11;52(42):11149-53. doi: 10.1002/anie.201306118. Epub 2013 Sep 4.

PMID:
24006204
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.

Wiener R, DiBello AT, Lombardi PM, Guzzo CM, Zhang X, Matunis MJ, Wolberger C.

Nat Struct Mol Biol. 2013 Sep;20(9):1033-9. doi: 10.1038/nsmb.2655. Epub 2013 Aug 18.

PMID:
23955022
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy.

García-Santisteban I, Peters GJ, Giovannetti E, Rodríguez JA.

Mol Cancer. 2013 Aug 10;12:91. doi: 10.1186/1476-4598-12-91. Review.

PMID:
23937906
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.

Mevissen TE, Hospenthal MK, Geurink PP, Elliott PR, Akutsu M, Arnaudo N, Ekkebus R, Kulathu Y, Wauer T, El Oualid F, Freund SM, Ovaa H, Komander D.

Cell. 2013 Jul 3;154(1):169-84. doi: 10.1016/j.cell.2013.05.046.

PMID:
23827681
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin.

Keusekotten K, Elliott PR, Glockner L, Fiil BK, Damgaard RB, Kulathu Y, Wauer T, Hospenthal MK, Gyrd-Hansen M, Krappmann D, Hofmann K, Komander D.

Cell. 2013 Jun 6;153(6):1312-26. doi: 10.1016/j.cell.2013.05.014.

PMID:
23746843
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Assembly, analysis and architecture of atypical ubiquitin chains.

Hospenthal MK, Freund SM, Komander D.

Nat Struct Mol Biol. 2013 May;20(5):555-65. doi: 10.1038/nsmb.2547. Epub 2013 Apr 7.

PMID:
23563141
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

OTUB1 modulates c-IAP1 stability to regulate signalling pathways.

Goncharov T, Niessen K, de Almagro MC, Izrael-Tomasevic A, Fedorova AV, Varfolomeev E, Arnott D, Deshayes K, Kirkpatrick DS, Vucic D.

EMBO J. 2013 Apr 17;32(8):1103-14. doi: 10.1038/emboj.2013.62. Epub 2013 Mar 22.

PMID:
23524849
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A strategy for modulation of enzymes in the ubiquitin system.

Ernst A, Avvakumov G, Tong J, Fan Y, Zhao Y, Alberts P, Persaud A, Walker JR, Neculai AM, Neculai D, Vorobyov A, Garg P, Beatty L, Chan PK, Juang YC, Landry MC, Yeh C, Zeqiraj E, Karamboulas K, Allali-Hassani A, Vedadi M, Tyers M, Moffat J, Sicheri F, Pelletier L, Durocher D, Raught B, Rotin D, Yang J, Moran MF, Dhe-Paganon S, Sidhu SS.

Science. 2013 Feb 1;339(6119):590-5. doi: 10.1126/science.1230161. Epub 2013 Jan 3.

PMID:
23287719
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Ubiquitin chain conformation regulates recognition and activity of interacting proteins.

Ye Y, Blaser G, Horrocks MH, Ruedas-Rama MJ, Ibrahim S, Zhukov AA, Orte A, Klenerman D, Jackson SE, Komander D.

Nature. 2012 Dec 13;492(7428):266-70. doi: 10.1038/nature11722. Epub 2012 Dec 2.

PMID:
23201676
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Nonenzymatic polymerization of ubiquitin: single-step synthesis and isolation of discrete ubiquitin oligomers.

Trang VH, Valkevich EM, Minami S, Chen YC, Ge Y, Strieter ER.

Angew Chem Int Ed Engl. 2012 Dec 21;51(52):13085-8. doi: 10.1002/anie.201207171. Epub 2012 Nov 19.

PMID:
23161800
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A role for intersubunit interactions in maintaining SAGA deubiquitinating module structure and activity.

Samara NL, Ringel AE, Wolberger C.

Structure. 2012 Aug 8;20(8):1414-24. doi: 10.1016/j.str.2012.05.015. Epub 2012 Jul 5.

PMID:
22771212
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Emerging role of ubiquitination in antiviral RIG-I signaling.

Maelfait J, Beyaert R.

Microbiol Mol Biol Rev. 2012 Mar;76(1):33-45. doi: 10.1128/MMBR.05012-11. Review.

PMID:
22390971
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The mechanism of OTUB1-mediated inhibition of ubiquitination.

Wiener R, Zhang X, Wang T, Wolberger C.

Nature. 2012 Feb 22;483(7391):618-22. doi: 10.1038/nature10911.

PMID:
22367539
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function.

Juang YC, Landry MC, Sanches M, Vittal V, Leung CC, Ceccarelli DF, Mateo AR, Pruneda JN, Mao DY, Szilard RK, Orlicky S, Munro M, Brzovic PS, Klevit RE, Sicheri F, Durocher D.

Mol Cell. 2012 Feb 10;45(3):384-97. doi: 10.1016/j.molcel.2012.01.011. Erratum in: Mol Cell. 2012 May 25;46(4):549.

PMID:
22325355
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

OTUB1 overexpression in mesangial cells is a novel regulator in the pathogenesis of glomerulonephritis through the decrease of DCN level.

Zhang Y, Hu R, Wu H, Jiang W, Sun Y, Wang Y, Song Y, Jin T, Zhang H, Mao X, Zhao Z, Zhang Z.

PLoS One. 2012;7(1):e29654. doi: 10.1371/journal.pone.0029654. Epub 2012 Jan 18.

PMID:
22279542
[PubMed - indexed for MEDLINE]
Free PMC Article

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