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Results: 1 to 20 of 151

Cited In for PubMed (Select 18854158)


Synthetic viability genomic screening defines Sae2 function in DNA repair.

Puddu F, Oelschlaegel T, Guerini I, Geisler NJ, Niu H, Herzog M, Salguero I, Ochoa-Montaño B, Viré E, Sung P, Adams DJ, Keane TM, Jackson SP.

EMBO J. 2015 Jun 3;34(11):1509-22. doi: 10.15252/embj.201590973. Epub 2015 Apr 21.


Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease.

Grieves JL, Fye JM, Harvey S, Grayson JM, Hollis T, Perrino FW.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5117-22. doi: 10.1073/pnas.1423804112. Epub 2015 Apr 6.


Sae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling.

Chen H, Donnianni RA, Handa N, Deng SK, Oh J, Timashev LA, Kowalczykowski SC, Symington LS.

Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):E1880-7. doi: 10.1073/pnas.1503331112. Epub 2015 Mar 23.


Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks.

Kim TM, Son MY, Dodds S, Hu L, Hasty P.

Mutat Res. 2014 Aug-Sep;766-767:66-72. doi: 10.1016/j.mrfmmm.2014.06.003. Epub 2014 Jun 22.


Replication fork integrity and intra-S phase checkpoint suppress gene amplification.

Kondratova A, Watanabe T, Marotta M, Cannon M, Segall AM, Serre D, Tanaka H.

Nucleic Acids Res. 2015 Mar 11;43(5):2678-90. doi: 10.1093/nar/gkv084. Epub 2015 Feb 11.


Tetrameric Ctp1 coordinates DNA binding and DNA bridging in DNA double-strand-break repair.

Andres SN, Appel CD, Westmoreland JW, Williams JS, Nguyen Y, Robertson PD, Resnick MA, Williams RS.

Nat Struct Mol Biol. 2015 Feb;22(2):158-66. doi: 10.1038/nsmb.2945. Epub 2015 Jan 12.


Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair.

Lafrance-Vanasse J, Williams GJ, Tainer JA.

Prog Biophys Mol Biol. 2015 Mar;117(2-3):182-93. doi: 10.1016/j.pbiomolbio.2014.12.004. Epub 2015 Jan 7. Review.


Bcl2 inhibits recruitment of Mre11 complex to DNA double-strand breaks in response to high-linear energy transfer radiation.

Xie M, Park D, You S, Li R, Owonikoko TK, Wang Y, Doetsch PW, Deng X.

Nucleic Acids Res. 2015 Jan;43(2):960-72. doi: 10.1093/nar/gku1358. Epub 2015 Jan 7.


RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway.

Kim TM, Son MY, Dodds S, Hu L, Luo G, Hasty P.

Nucleic Acids Res. 2015 Jan;43(2):893-903. doi: 10.1093/nar/gku1334. Epub 2014 Dec 17.


Structural insights into 5' flap DNA unwinding and incision by the human FAN1 dimer.

Zhao Q, Xue X, Longerich S, Sung P, Xiong Y.

Nat Commun. 2014 Dec 11;5:5726. doi: 10.1038/ncomms6726.


Structure of the Rad50 DNA double-strand break repair protein in complex with DNA.

Rojowska A, Lammens K, Seifert FU, Direnberger C, Feldmann H, Hopfner KP.

EMBO J. 2014 Dec 1;33(23):2847-59. doi: 10.15252/embj.201488889. Epub 2014 Oct 27.


Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1.

Gwon GH, Kim Y, Liu Y, Watson AT, Jo A, Etheridge TJ, Yuan F, Zhang Y, Kim Y, Carr AM, Cho Y.

Genes Dev. 2014 Oct 15;28(20):2276-90. doi: 10.1101/gad.248492.114.


MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon cancer patients in randomized CALGB 89803 trial.

Pavelitz T, Renfro L, Foster NR, Caracol A, Welsch P, Lao VV, Grady WB, Niedzwiecki D, Saltz LB, Bertagnolli MM, Goldberg RM, Rabinovitch PS, Emond M, Monnat RJ Jr, Maizels N.

PLoS One. 2014 Oct 13;9(10):e108483. doi: 10.1371/journal.pone.0108483. eCollection 2014.


Distinct roles of Ape1 protein, an enzyme involved in DNA repair, in high or low linear energy transfer ionizing radiation-induced cell killing.

Wang H, Wang X, Chen G, Zhang X, Tang X, Park D, Cucinotta FA, Yu DS, Deng X, Dynan WS, Doetsch PW, Wang Y.

J Biol Chem. 2014 Oct 31;289(44):30635-44. doi: 10.1074/jbc.M114.604959. Epub 2014 Sep 10.


Multifaceted role of the Topo IIIα-RMI1-RMI2 complex and DNA2 in the BLM-dependent pathway of DNA break end resection.

Daley JM, Chiba T, Xue X, Niu H, Sung P.

Nucleic Acids Res. 2014;42(17):11083-91. doi: 10.1093/nar/gku803. Epub 2014 Sep 8.


Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1.

Montemayor EJ, Katolik A, Clark NE, Taylor AB, Schuermann JP, Combs DJ, Johnsson R, Holloway SP, Stevens SW, Damha MJ, Hart PJ.

Nucleic Acids Res. 2014;42(16):10845-55. doi: 10.1093/nar/gku725. Epub 2014 Aug 14.


Recognition and repair of chemically heterogeneous structures at DNA ends.

Andres SN, Schellenberg MJ, Wallace BD, Tumbale P, Williams RS.

Environ Mol Mutagen. 2015 Jan;56(1):1-21. doi: 10.1002/em.21892. Epub 2014 Aug 11. Review.


DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA.

Sung S, Li F, Park YB, Kim JS, Kim AK, Song OK, Kim J, Che J, Lee SE, Cho Y.

EMBO J. 2014 Oct 16;33(20):2422-35. doi: 10.15252/embj.201488299. Epub 2014 Aug 8.


Autoinhibition of bacteriophage T4 Mre11 by its C-terminal domain.

Gao Y, Nelson SW.

J Biol Chem. 2014 Sep 19;289(38):26505-13. doi: 10.1074/jbc.M114.583625. Epub 2014 Jul 30.

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