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Results: 1 to 20 of 38

1.

Reducing cannabinoid abuse and preventing relapse by enhancing endogenous brain levels of kynurenic acid.

Justinova Z, Mascia P, Wu HQ, Secci ME, Redhi GH, Panlilio LV, Scherma M, Barnes C, Parashos A, Zara T, Fratta W, Solinas M, Pistis M, Bergman J, Kangas BD, Ferré S, Tanda G, Schwarcz R, Goldberg SR.

Nat Neurosci. 2013 Nov;16(11):1652-61. doi: 10.1038/nn.3540. Epub 2013 Oct 13.

PMID:
24121737
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Modulation of the endocannabinoid system: vulnerability factor and new treatment target for stimulant addiction.

Olière S, Joliette-Riopel A, Potvin S, Jutras-Aswad D.

Front Psychiatry. 2013 Sep 23;4:109. doi: 10.3389/fpsyt.2013.00109. Review.

PMID:
24069004
[PubMed]
Free PMC Article
3.

The endocannabinoid system as a possible target to treat both the cognitive and emotional features of post-traumatic stress disorder (PTSD).

Trezza V, Campolongo P.

Front Behav Neurosci. 2013 Aug 9;7:100. doi: 10.3389/fnbeh.2013.00100. eCollection 2013.

PMID:
23950739
[PubMed]
Free PMC Article
4.

Development and characterization of a promising fluorine-18 labelled radiopharmaceutical for in vivo imaging of fatty acid amide hydrolase.

Sadovski O, Hicks JW, Parkes J, Raymond R, Nobrega J, Houle S, Cipriano M, Fowler CJ, Vasdev N, Wilson AA.

Bioorg Med Chem. 2013 Jul 15;21(14):4351-7. doi: 10.1016/j.bmc.2013.04.077. Epub 2013 May 7.

PMID:
23712084
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Chemical probes of endocannabinoid metabolism.

Blankman JL, Cravatt BF.

Pharmacol Rev. 2013 Mar 19;65(2):849-71. doi: 10.1124/pr.112.006387. Print 2013 Apr. Review.

PMID:
23512546
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Marijuana dependence: not just smoke and mirrors.

Ramesh D, Schlosburg JE, Wiebelhaus JM, Lichtman AH.

ILAR J. 2011;52:295-308. doi: 10.1093/ilar.52.3.295.

PMID:
23382144
[PubMed - in process]
Free PMC Article
7.

Inhibition of FAAH and activation of PPAR: new approaches to the treatment of cognitive dysfunction and drug addiction.

Panlilio LV, Justinova Z, Goldberg SR.

Pharmacol Ther. 2013 Apr;138(1):84-102. doi: 10.1016/j.pharmthera.2013.01.003. Epub 2013 Jan 16. Review.

PMID:
23333350
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Hub and switches: endocannabinoid signalling in midbrain dopamine neurons.

Melis M, Pistis M.

Philos Trans R Soc Lond B Biol Sci. 2012 Dec 5;367(1607):3276-85. doi: 10.1098/rstb.2011.0383. Review.

PMID:
23108546
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A polymorphism in the gene of the endocannabinoid-degrading enzyme FAAH (FAAH C385A) is associated with emotional-motivational reactivity.

Conzelmann A, Reif A, Jacob C, Weyers P, Lesch KP, Lutz B, Pauli P.

Psychopharmacology (Berl). 2012 Dec;224(4):573-9. doi: 10.1007/s00213-012-2785-y. Epub 2012 Jul 10.

PMID:
22776995
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence.

Muldoon PP, Lichtman AH, Parsons LH, Damaj MI.

Life Sci. 2013 Mar 19;92(8-9):458-62. doi: 10.1016/j.lfs.2012.05.015. Epub 2012 Jun 12. Review.

PMID:
22705310
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Lack of effect of chronic pre-treatment with the FAAH inhibitor URB597 on inflammatory pain behaviour: evidence for plastic changes in the endocannabinoid system.

Okine BN, Norris LM, Woodhams S, Burston J, Patel A, Alexander SP, Barrett DA, Kendall DA, Bennett AJ, Chapman V.

Br J Pharmacol. 2012 Oct;167(3):627-40. doi: 10.1111/j.1476-5381.2012.02028.x.

PMID:
22595021
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Monoacylglycerol lipase - a target for drug development?

Fowler CJ.

Br J Pharmacol. 2012 Jul;166(5):1568-85. doi: 10.1111/j.1476-5381.2012.01950.x. Review.

PMID:
22428756
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Endocannabinoids and the processing of value-related signals.

Melis M, Muntoni AL, Pistis M.

Front Pharmacol. 2012 Feb 2;3:7. doi: 10.3389/fphar.2012.00007. eCollection 2012.

PMID:
22347186
[PubMed]
Free PMC Article
14.

Cannabinoid-related agents in the treatment of anxiety disorders: current knowledge and future perspectives.

Tambaro S, Bortolato M.

Recent Pat CNS Drug Discov. 2012 Apr 1;7(1):25-40. Review.

PMID:
22280339
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors.

Serrano A, Parsons LH.

Pharmacol Ther. 2011 Dec;132(3):215-41. doi: 10.1016/j.pharmthera.2011.06.005. Epub 2011 Jul 18. Review.

PMID:
21798285
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice.

Kinsey SG, Naidu PS, Cravatt BF, Dudley DT, Lichtman AH.

Pharmacol Biochem Behav. 2011 Oct;99(4):718-25. doi: 10.1016/j.pbb.2011.06.022. Epub 2011 Jun 29.

PMID:
21740924
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice.

Ramesh D, Ross GR, Schlosburg JE, Owens RA, Abdullah RA, Kinsey SG, Long JZ, Nomura DK, Sim-Selley LJ, Cravatt BF, Akbarali HI, Lichtman AH.

J Pharmacol Exp Ther. 2011 Oct;339(1):173-85. doi: 10.1124/jpet.111.181370. Epub 2011 Jun 30.

PMID:
21719468
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The endogenous cannabinoid 2-arachidonoylglycerol is intravenously self-administered by squirrel monkeys.

Justinová Z, Yasar S, Redhi GH, Goldberg SR.

J Neurosci. 2011 May 11;31(19):7043-8. doi: 10.1523/JNEUROSCI.6058-10.2011.

PMID:
21562266
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The fatty acid amide hydrolase inhibitor URB 597: interactions with anandamide in rhesus monkeys.

Stewart JL, McMahon LR.

Br J Pharmacol. 2011 Sep;164(2b):655-66. doi: 10.1111/j.1476-5381.2011.01388.x.

PMID:
21449917
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Drug addiction.

Justinova Z, Panlilio LV, Goldberg SR.

Curr Top Behav Neurosci. 2009;1:309-46. doi: 10.1007/978-3-540-88955-7_13. Review.

PMID:
21104390
[PubMed - indexed for MEDLINE]
Free PMC Article

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