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Items: 1 to 20 of 23


Discovering Genes Essential to the Hypothalamic Regulation of Human Reproduction Using a Human Disease Model: Adjusting to Life in the "-Omics" Era.

Stamou MI, Cox KH, Crowley WF Jr.

Endocr Rev. 2015 Dec;36(6):603-21. doi: 10.1210/er.2015-1045. Epub 2015 Sep 22.


Genome-Wide Specific Selection in Three Domestic Sheep Breeds.

Wang H, Zhang L, Cao J, Wu M, Ma X, Liu Z, Liu R, Zhao F, Wei C, Du L.

PLoS One. 2015 Jun 17;10(6):e0128688. doi: 10.1371/journal.pone.0128688. eCollection 2015.


Novel Interaction of Class IIb Histone Deacetylase 6 (HDAC6) with Class IIa HDAC9 Controls Gonadotropin Releasing Hormone (GnRH) Neuronal Cell Survival and Movement.

Salian-Mehta S, Xu M, McKinsey TA, Tobet S, Wierman ME.

J Biol Chem. 2015 May 29;290(22):14045-56. doi: 10.1074/jbc.M115.640482. Epub 2015 Apr 14.


TAM receptor deficiency affects adult hippocampal neurogenesis.

Ji R, Meng L, Li Q, Lu Q.

Metab Brain Dis. 2015 Jun;30(3):633-44. doi: 10.1007/s11011-014-9636-y. Epub 2014 Dec 10.


Axl as a mediator of cellular growth and survival.

Axelrod H, Pienta KJ.

Oncotarget. 2014 Oct 15;5(19):8818-52. Review.


Loss of Growth arrest specific gene 6 (Gas6) results in altered GnRH neuron migration, delayed vaginal opening and sexual maturation in mice.

Salian-Mehta S, Xu M, Pierce A, Bliesner B, Tobet S, Wierman ME.

Mol Cell Endocrinol. 2014 Aug 5;393(1-2):164-70. doi: 10.1016/j.mce.2014.06.015. Epub 2014 Jun 27.


Functional consequences of AXL sequence variants in hypogonadotropic hypogonadism.

Salian-Mehta S, Xu M, Knox AJ, Plummer L, Slavov D, Taylor M, Bevers S, Hodges RS, Crowley WF Jr, Wierman ME.

J Clin Endocrinol Metab. 2014 Apr;99(4):1452-60. doi: 10.1210/jc.2013-3426. Epub 2014 Jan 29.


Maternal dexamethasone exposure during pregnancy in rats disrupts gonadotropin-releasing hormone neuronal development in the offspring.

Lim WL, Soga T, Parhar IS.

Cell Tissue Res. 2014 Feb;355(2):409-23. doi: 10.1007/s00441-013-1765-9. Epub 2013 Dec 28.


Biology of the TAM receptors.

Lemke G.

Cold Spring Harb Perspect Biol. 2013 Nov 1;5(11):a009076. doi: 10.1101/cshperspect.a009076. Review.


TAM receptor tyrosine kinases: expression, disease and oncogenesis in the central nervous system.

Pierce AM, Keating AK.

Brain Res. 2014 Jan 13;1542:206-20. doi: 10.1016/j.brainres.2013.10.049. Epub 2013 Nov 1. Review.


AXL and MET crosstalk to promote gonadotropin releasing hormone (GnRH) neuronal cell migration and survival.

Salian-Mehta S, Xu M, Wierman ME.

Mol Cell Endocrinol. 2013 Jul 15;374(1-2):92-100. doi: 10.1016/j.mce.2013.04.018. Epub 2013 May 3.


Netrin-1 stimulates developing GnRH neurons to extend neurites to the median eminence in a calcium- dependent manner.

Low VF, Fiorini Z, Fisher L, Jasoni CL.

PLoS One. 2012;7(10):e46999. doi: 10.1371/journal.pone.0046999. Epub 2012 Oct 9.


Cross-phosphorylation, signaling and proliferative functions of the Tyro3 and Axl receptors in Rat2 cells.

Brown JE, Krodel M, Pazos M, Lai C, Prieto AL.

PLoS One. 2012;7(5):e36800. doi: 10.1371/journal.pone.0036800. Epub 2012 May 14.


VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels.

Cariboni A, Davidson K, Dozio E, Memi F, Schwarz Q, Stossi F, Parnavelas JG, Ruhrberg C.

Development. 2011 Sep;138(17):3723-33. doi: 10.1242/dev.063362.


Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA.

Mackiewicz M, Huppi K, Pitt JJ, Dorsey TH, Ambs S, Caplen NJ.

Breast Cancer Res Treat. 2011 Nov;130(2):663-79. doi: 10.1007/s10549-011-1690-0. Epub 2011 Aug 4.


Hypothalamic but not pituitary or ovarian defects underlie the reproductive abnormalities in Axl/Tyro3 null mice.

Pierce A, Xu M, Bliesner B, Liu Z, Richards J, Tobet S, Wierman ME.

Mol Cell Endocrinol. 2011 Jun 6;339(1-2):151-8. doi: 10.1016/j.mce.2011.04.007. Epub 2011 Apr 22.


Deletion of Otx2 in GnRH neurons results in a mouse model of hypogonadotropic hypogonadism.

Diaczok D, DiVall S, Matsuo I, Wondisford FE, Wolfe AM, Radovick S.

Mol Endocrinol. 2011 May;25(5):833-46. doi: 10.1210/me.2010-0271. Epub 2011 Mar 24.


Hypothalamic dysregulation and infertility in mice lacking the homeodomain protein Six6.

Larder R, Clark DD, Miller NL, Mellon PL.

J Neurosci. 2011 Jan 12;31(2):426-38. doi: 10.1523/JNEUROSCI.1688-10.2011.


Protein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-phosphatidylinositol 3-kinase-Akt pathway through its sex hormone-binding globulin-like region.

Zhong Z, Wang Y, Guo H, Sagare A, Fernández JA, Bell RD, Barrett TM, Griffin JH, Freeman RS, Zlokovic BV.

J Neurosci. 2010 Nov 17;30(46):15521-34. doi: 10.1523/JNEUROSCI.4437-10.2010.


Gonadotropin-releasing hormone (GnRH) neuron migration: initiation, maintenance and cessation as critical steps to ensure normal reproductive function.

Wierman ME, Kiseljak-Vassiliades K, Tobet S.

Front Neuroendocrinol. 2011 Jan;32(1):43-52. doi: 10.1016/j.yfrne.2010.07.005. Epub 2010 Jul 30. Review.

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