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Results: 20

1.

Up-regulated FASN expression promotes transcoelomic metastasis of ovarian cancer cell through epithelial-mesenchymal transition.

Jiang L, Wang H, Li J, Fang X, Pan H, Yuan X, Zhang P.

Int J Mol Sci. 2014 Jun 27;15(7):11539-54. doi: 10.3390/ijms150711539.

PMID:
24979135
[PubMed - in process]
Free PMC Article
2.

Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic melan-a cells associated with inhibition of mitochondrial respiration.

Rossato FA, Zecchin KG, La Guardia PG, Ortega RM, Alberici LC, Costa RA, Catharino RR, Graner E, Castilho RF, Vercesi AE.

PLoS One. 2014 Jun 25;9(6):e101060. doi: 10.1371/journal.pone.0101060. eCollection 2014.

PMID:
24964211
[PubMed - in process]
Free PMC Article
3.

Myelopoietic efficacy of orlistat in murine hosts bearing T cell lymphoma: implication in macrophage differentiation and activation.

Kant S, Kumar A, Singh SM.

PLoS One. 2013 Dec 3;8(12):e82396. doi: 10.1371/journal.pone.0082396. eCollection 2013.

PMID:
24349275
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Fatty acid synthase is a key target in multiple essential tumor functions of prostate cancer: uptake of radiolabeled acetate as a predictor of the targeted therapy outcome.

Yoshii Y, Furukawa T, Oyama N, Hasegawa Y, Kiyono Y, Nishii R, Waki A, Tsuji AB, Sogawa C, Wakizaka H, Fukumura T, Yoshii H, Fujibayashi Y, Lewis JS, Saga T.

PLoS One. 2013 May 31;8(5):e64570. doi: 10.1371/journal.pone.0064570. Print 2013.

PMID:
23741342
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Tumor suppressive microRNA-424 inhibits osteosarcoma cell migration and invasion via targeting fatty acid synthase.

Long XH, Mao JH, Peng AF, Zhou Y, Huang SH, Liu ZL.

Exp Ther Med. 2013 Apr;5(4):1048-1052. Epub 2013 Feb 18.

PMID:
23599729
[PubMed]
Free PMC Article
6.

Proteomics of genetically engineered mouse mammary tumors identifies fatty acid metabolism members as potential predictive markers for cisplatin resistance.

Warmoes M, Jaspers JE, Xu G, Sampadi BK, Pham TV, Knol JC, Piersma SR, Boven E, Jonkers J, Rottenberg S, Jimenez CR.

Mol Cell Proteomics. 2013 May;12(5):1319-34. doi: 10.1074/mcp.M112.024182. Epub 2013 Feb 8.

PMID:
23397111
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Altered energy metabolism in cancer: a unique opportunity for therapeutic intervention.

Zhang Y, Yang JM.

Cancer Biol Ther. 2013 Feb;14(2):81-9. doi: 10.4161/cbt.22958. Epub 2012 Nov 28. Review.

PMID:
23192270
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

microRNA-195 suppresses osteosarcoma cell invasion and migration in vitro by targeting FASN.

Mao JH, Zhou RP, Peng AF, Liu ZL, Huang SH, Long XH, Shu Y.

Oncol Lett. 2012 Nov;4(5):1125-1129. Epub 2012 Aug 16.

PMID:
23162665
[PubMed]
Free PMC Article
9.

Fatty acid synthase expression in osteosarcoma and its correlation with pulmonary metastasis.

Liu ZL, Wang G, Peng AF, Luo QF, Zhou Y, Huang SH.

Oncol Lett. 2012 Nov;4(5):878-882. Epub 2012 Aug 14.

PMID:
23162615
[PubMed]
Free PMC Article
10.

The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas.

Seguin F, Carvalho MA, Bastos DC, Agostini M, Zecchin KG, Alvarez-Flores MP, Chudzinski-Tavassi AM, Coletta RD, Graner E.

Br J Cancer. 2012 Sep 4;107(6):977-87. doi: 10.1038/bjc.2012.355. Epub 2012 Aug 14.

PMID:
22892389
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Glutamine-fueled mitochondrial metabolism is decoupled from glycolysis in melanoma.

Filipp FV, Ratnikov B, De Ingeniis J, Smith JW, Osterman AL, Scott DA.

Pigment Cell Melanoma Res. 2012 Nov;25(6):732-9. doi: 10.1111/pcmr.12000. Epub 2012 Oct 1. Review.

PMID:
22846158
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer.

Zaytseva YY, Rychahou PG, Gulhati P, Elliott VA, Mustain WC, O'Connor K, Morris AJ, Sunkara M, Weiss HL, Lee EY, Evers BM.

Cancer Res. 2012 Mar 15;72(6):1504-17. doi: 10.1158/0008-5472.CAN-11-4057. Epub 2012 Jan 19.

PMID:
22266115
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesity.

Navina S, Acharya C, DeLany JP, Orlichenko LS, Baty CJ, Shiva SS, Durgampudi C, Karlsson JM, Lee K, Bae KT, Furlan A, Behari J, Liu S, McHale T, Nichols L, Papachristou GI, Yadav D, Singh VP.

Sci Transl Med. 2011 Nov 2;3(107):107ra110. doi: 10.1126/scitranslmed.3002573.

PMID:
22049070
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The use of chemokine-releasing tissue engineering scaffolds in a model of inflammatory response-mediated melanoma cancer metastasis.

Ko CY, Wu L, Nair AM, Tsai YT, Lin VK, Tang L.

Biomaterials. 2012 Jan;33(3):876-85. doi: 10.1016/j.biomaterials.2011.10.002. Epub 2011 Oct 22.

PMID:
22019117
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Inhibition of SREBP1 sensitizes cells to death ligands.

Eberhard Y, Gronda M, Hurren R, Datti A, MacLean N, Ketela T, Moffat J, Wrana JL, Schimmer AD.

Oncotarget. 2011 Mar;2(3):186-96.

PMID:
21406729
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Metabolic alterations and targeted therapies in prostate cancer.

Flavin R, Zadra G, Loda M.

J Pathol. 2011 Jan;223(2):283-94. doi: 10.1002/path.2809. Epub 2010 Nov 16. Review.

PMID:
21125681
[PubMed - indexed for MEDLINE]
Free PMC Article
17.
18.

Fatty acid synthase as a potential therapeutic target in cancer.

Flavin R, Peluso S, Nguyen PL, Loda M.

Future Oncol. 2010 Apr;6(4):551-62. doi: 10.2217/fon.10.11. Review.

PMID:
20373869
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

p63 promotes cell survival through fatty acid synthase.

Sabbisetti V, Di Napoli A, Seeley A, Amato AM, O'Regan E, Ghebremichael M, Loda M, Signoretti S.

PLoS One. 2009 Jun 11;4(6):e5877. doi: 10.1371/journal.pone.0005877.

PMID:
19517019
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer.

Migita T, Ruiz S, Fornari A, Fiorentino M, Priolo C, Zadra G, Inazuka F, Grisanzio C, Palescandolo E, Shin E, Fiore C, Xie W, Kung AL, Febbo PG, Subramanian A, Mucci L, Ma J, Signoretti S, Stampfer M, Hahn WC, Finn S, Loda M.

J Natl Cancer Inst. 2009 Apr 1;101(7):519-32. doi: 10.1093/jnci/djp030. Epub 2009 Mar 24.

PMID:
19318631
[PubMed - indexed for MEDLINE]
Free PMC Article

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