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PAX5-KIAA1549L: a novel fusion gene in a case of pediatric B-cell precursor acute lymphoblastic leukemia.

Anderl S, König M, Attarbaschi A, Strehl S.

Mol Cytogenet. 2015 Jul 8;8:48. doi: 10.1186/s13039-015-0138-3. eCollection 2015.


The role of the Janus-faced transcription factor PAX5-JAK2 in acute lymphoblastic leukemia.

Schinnerl D, Fortschegger K, Kauer M, Marchante JR, Kofler R, Den Boer ML, Strehl S.

Blood. 2015 Feb 19;125(8):1282-91. doi: 10.1182/blood-2014-04-570960. Epub 2014 Dec 16.


PAX5 fusion genes in t(7;9)(q11.2;p13) leukemia: a case report and review of the literature.

Denk D, Bradtke J, König M, Strehl S.

Mol Cytogenet. 2014 Feb 7;7(1):13. doi: 10.1186/1755-8166-7-13.


Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma.

Gu DL, Chen YH, Shih JH, Lin CH, Jou YS, Chen CF.

World J Gastroenterol. 2013 Dec 21;19(47):8873-9. doi: 10.3748/wjg.v19.i47.8873. Review.


The role of AUTS2 in neurodevelopment and human evolution.

Oksenberg N, Ahituv N.

Trends Genet. 2013 Oct;29(10):600-8. doi: 10.1016/j.tig.2013.08.001. Epub 2013 Sep 2. Review.


Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types.

Giacomini CP, Sun S, Varma S, Shain AH, Giacomini MM, Balagtas J, Sweeney RT, Lai E, Del Vecchio CA, Forster AD, Clarke N, Montgomery KD, Zhu S, Wong AJ, van de Rijn M, West RB, Pollack JR.

PLoS Genet. 2013 Apr;9(4):e1003464. doi: 10.1371/journal.pgen.1003464. Epub 2013 Apr 25.


Characterization of genetic rearrangements in esophageal squamous carcinoma cell lines by a combination of M-FISH and array-CGH: further confirmation of some split genomic regions in primary tumors.

Hao JJ, Shi ZZ, Zhao ZX, Zhang Y, Gong T, Li CX, Zhan T, Cai Y, Dong JT, Fu SB, Zhan QM, Wang MR.

BMC Cancer. 2012 Aug 24;12:367. doi: 10.1186/1471-2407-12-367.


IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia.

Iacobucci I, Iraci N, Messina M, Lonetti A, Chiaretti S, Valli E, Ferrari A, Papayannidis C, Paoloni F, Vitale A, Storlazzi CT, Ottaviani E, Guadagnuolo V, Durante S, Vignetti M, Soverini S, Pane F, Foà R, Baccarani M, Müschen M, Perini G, Martinelli G.

PLoS One. 2012;7(7):e40934. doi: 10.1371/journal.pone.0040934. Epub 2012 Jul 25.


PAX5-AUTS2: a recurrent fusion gene in childhood B-cell precursor acute lymphoblastic leukemia.

Denk D, Nebral K, Bradtke J, Pass G, Möricke A, Attarbaschi A, Strehl S.

Leuk Res. 2012 Aug;36(8):e178-81. doi: 10.1016/j.leukres.2012.04.015. Epub 2012 May 12. Review.


The role of dicentric chromosome formation and secondary centromere deletion in the evolution of myeloid malignancy.

Mackinnon RN, Campbell LJ.

Genet Res Int. 2011;2011:643628. doi: 10.4061/2011/643628. Epub 2011 Sep 27.


Dominant-negative mechanism of leukemogenic PAX5 fusions.

Kawamata N, Pennella MA, Woo JL, Berk AJ, Koeffler HP.

Oncogene. 2012 Feb 23;31(8):966-77. doi: 10.1038/onc.2011.291. Epub 2011 Jul 18.


The use of ultra-dense array CGH analysis for the discovery of micro-copy number alterations and gene fusions in the cancer genome.

Przybytkowski E, Ferrario C, Basik M.

BMC Med Genomics. 2011 Jan 27;4:16. doi: 10.1186/1755-8794-4-16.


Genome-wide Mapping of Copy Number Variations Using SNP Arrays.

Nowak D, Hofmann WK, Koeffler HP.

Transfus Med Hemother. 2009;36(4):246-251. Epub 2009 Jul 10.


Acquired genomic copy number aberrations and survival in adult acute myelogenous leukemia.

Parkin B, Erba H, Ouillette P, Roulston D, Purkayastha A, Karp J, Talpaz M, Kujawski L, Shakhan S, Li C, Shedden K, Malek SN.

Blood. 2010 Dec 2;116(23):4958-67. doi: 10.1182/blood-2010-01-266999. Epub 2010 Aug 20.


The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party.

Iacobucci I, Lonetti A, Paoloni F, Papayannidis C, Ferrari A, Storlazzi CT, Vignetti M, Cilloni D, Messa F, Guadagnuolo V, Paolini S, Elia L, Messina M, Vitale A, Meloni G, Soverini S, Pane F, Baccarani M, Foà R, Martinelli G.

Haematologica. 2010 Oct;95(10):1683-90. doi: 10.3324/haematol.2009.020792. Epub 2010 Jun 9.


NF1 inactivation in adult acute myelogenous leukemia.

Parkin B, Ouillette P, Wang Y, Liu Y, Wright W, Roulston D, Purkayastha A, Dressel A, Karp J, Bockenstedt P, Al-Zoubi A, Talpaz M, Kujawski L, Liu Y, Shedden K, Shakhan S, Li C, Erba H, Malek SN.

Clin Cancer Res. 2010 Aug 15;16(16):4135-47. doi: 10.1158/1078-0432.CCR-09-2639. Epub 2010 May 26.


Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia.

Okamoto R, Ogawa S, Nowak D, Kawamata N, Akagi T, Kato M, Sanada M, Weiss T, Haferlach C, Dugas M, Ruckert C, Haferlach T, Koeffler HP.

Haematologica. 2010 Sep;95(9):1481-8. doi: 10.3324/haematol.2009.011114. Epub 2010 Apr 30.


Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function.

Trageser D, Iacobucci I, Nahar R, Duy C, von Levetzow G, Klemm L, Park E, Schuh W, Gruber T, Herzog S, Kim YM, Hofmann WK, Li A, Storlazzi CT, Jäck HM, Groffen J, Martinelli G, Heisterkamp N, Jumaa H, Müschen M.

J Exp Med. 2009 Aug 3;206(8):1739-53. doi: 10.1084/jem.20090004. Epub 2009 Jul 20.


Heterogeneous breakpoints in patients with acute lymphoblastic leukemia and the dic(9;20)(p11-13;q11) show recurrent involvement of genes at 20q11.21.

An Q, Wright SL, Moorman AV, Parker H, Griffiths M, Ross FM, Davies T, Harrison CJ, Strefford JC.

Haematologica. 2009 Aug;94(8):1164-9. doi: 10.3324/haematol.2008.002808. Epub 2009 Jul 7.


Molecular allelokaryotyping of T-cell prolymphocytic leukemia cells with high density single nucleotide polymorphism arrays identifies novel common genomic lesions and acquired uniparental disomy.

Nowak D, Le Toriellec E, Stern MH, Kawamata N, Akagi T, Dyer MJ, Hofmann WK, Ogawa S, Koeffler HP.

Haematologica. 2009 Apr;94(4):518-27. doi: 10.3324/haematol.2008.001347. Epub 2009 Mar 10.

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