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Exosome Cofactors Connect Transcription Termination to RNA Processing by Guiding Terminated Transcripts to the Appropriate Exonuclease within the Nuclear Exosome.

Kim K, Heo DH, Kim I, Suh JY, Kim M.

J Biol Chem. 2016 Jun 17;291(25):13229-42. doi: 10.1074/jbc.M116.715771. Epub 2016 Apr 13.


Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states.

Tan D, Li Q, Zhang MJ, Liu C, Ma C, Zhang P, Ding YH, Fan SB, Tao L, Yang B, Li X, Ma S, Liu J, Feng B, Liu X, Wang HW, He SM, Gao N, Ye K, Dong MQ, Lei X.

Elife. 2016 Mar 8;5. pii: e12509. doi: 10.7554/eLife.12509.


Rrp6: Integrated roles in nuclear RNA metabolism and transcription termination.

Fox MJ, Mosley AL.

Wiley Interdiscip Rev RNA. 2016 Jan-Feb;7(1):91-104. doi: 10.1002/wrna.1317. Epub 2015 Nov 26. Review.


Immature large ribosomal subunits containing the 7S pre-rRNA can engage in translation in Saccharomyces cerevisiae.

Rodríguez-Galán O, García-Gómez JJ, Kressler D, de la Cruz J.

RNA Biol. 2015;12(8):838-46. doi: 10.1080/15476286.2015.1058477.


Non-coding RNA: what is functional and what is junk?

Palazzo AF, Lee ES.

Front Genet. 2015 Jan 26;6:2. doi: 10.3389/fgene.2015.00002. eCollection 2015.


The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase.

Schuch B, Feigenbutz M, Makino DL, Falk S, Basquin C, Mitchell P, Conti E.

EMBO J. 2014 Dec 1;33(23):2829-46. doi: 10.15252/embj.201488757. Epub 2014 Oct 15.


The nuclear exosome is active and important during budding yeast meiosis.

Frenk S, Oxley D, Houseley J.

PLoS One. 2014 Sep 11;9(9):e107648. doi: 10.1371/journal.pone.0107648. eCollection 2014.


Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA.

Wasmuth EV, Januszyk K, Lima CD.

Nature. 2014 Jul 24;511(7510):435-9. doi: 10.1038/nature13406. Epub 2014 Jul 6.


The RNA exosome affects iron response and sensitivity to oxidative stress.

Tsanova B, Spatrick P, Jacobson A, van Hoof A.

RNA. 2014 Jul;20(7):1057-67. doi: 10.1261/rna.043257.113. Epub 2014 May 23.


The case for junk DNA.

Palazzo AF, Gregory TR.

PLoS Genet. 2014 May 8;10(5):e1004351. doi: 10.1371/journal.pgen.1004351. eCollection 2014 May. No abstract available.


The eukaryotic RNA exosome.

Januszyk K, Lima CD.

Curr Opin Struct Biol. 2014 Feb;24:132-40. doi: 10.1016/ Epub 2014 Feb 11. Review.


The exosome cofactor Rrp47 is critical for the stability and normal expression of its associated exoribonuclease Rrp6 in Saccharomyces cerevisiae.

Feigenbutz M, Garland W, Turner M, Mitchell P.

PLoS One. 2013 Nov 5;8(11):e80752. doi: 10.1371/journal.pone.0080752. eCollection 2013.


Rrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6.

Garland W, Feigenbutz M, Turner M, Mitchell P.

RNA. 2013 Dec;19(12):1659-68. doi: 10.1261/rna.039388.113. Epub 2013 Oct 8.


The Sm complex is required for the processing of non-coding RNAs by the exosome.

Coy S, Volanakis A, Shah S, Vasiljeva L.

PLoS One. 2013 Jun 6;8(6):e65606. doi: 10.1371/journal.pone.0065606. Print 2013.


Las1 interacts with Grc3 polynucleotide kinase and is required for ribosome synthesis in Saccharomyces cerevisiae.

Castle CD, Sardana R, Dandekar V, Borgianini V, Johnson AW, Denicourt C.

Nucleic Acids Res. 2013 Jan;41(2):1135-50. doi: 10.1093/nar/gks1086. Epub 2012 Nov 21.


The THO complex cooperates with the nuclear RNA surveillance machinery to control small nucleolar RNA expression.

Larochelle M, Lemay JF, Bachand F.

Nucleic Acids Res. 2012 Nov 1;40(20):10240-53. doi: 10.1093/nar/gks838. Epub 2012 Sep 10.


DExD/H-box RNA helicases in ribosome biogenesis.

Martin R, Straub AU, Doebele C, Bohnsack MT.

RNA Biol. 2013 Jan;10(1):4-18. doi: 10.4161/rna.21879. Epub 2012 Aug 24. Review.


RNA degradation in Saccharomyces cerevisae.

Parker R.

Genetics. 2012 Jul;191(3):671-702. doi: 10.1534/genetics.111.137265. Review.


Progenitor function in self-renewing human epidermis is maintained by the exosome.

Mistry DS, Chen Y, Sen GL.

Cell Stem Cell. 2012 Jul 6;11(1):127-35. doi: 10.1016/j.stem.2012.04.022.

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