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Update on Pyrin Functions and Mechanisms of Familial Mediterranean Fever.

Manukyan G, Aminov R.

Front Microbiol. 2016 Mar 31;7:456. doi: 10.3389/fmicb.2016.00456. eCollection 2016. Review.


Colchicine--Update on mechanisms of action and therapeutic uses.

Leung YY, Yao Hui LL, Kraus VB.

Semin Arthritis Rheum. 2015 Dec;45(3):341-50. doi: 10.1016/j.semarthrit.2015.06.013. Epub 2015 Jun 26. Review.


Caspase cleavage sites in the human proteome: CaspDB, a database of predicted substrates.

Kumar S, van Raam BJ, Salvesen GS, Cieplak P.

PLoS One. 2014 Oct 17;9(10):e110539. doi: 10.1371/journal.pone.0110539. eCollection 2014.


Increased frequency of Mediterranean fever gene variants in multiple myeloma.

Celik S, Tangi F, Oktenli C.

Oncol Lett. 2014 Oct;8(4):1735-1738. Epub 2014 Aug 4.


Monogenic autoinflammatory syndromes: state of the art on genetic, clinical, and therapeutic issues.

Caso F, Rigante D, Vitale A, Lucherini OM, Costa L, Atteno M, Compagnone A, Caso P, Frediani B, Galeazzi M, Punzi L, Cantarini L.

Int J Rheumatol. 2013;2013:513782. doi: 10.1155/2013/513782. Epub 2013 Oct 24. Review.


Caspase functions in cell death and disease.

McIlwain DR, Berger T, Mak TW.

Cold Spring Harb Perspect Biol. 2013 Apr 1;5(4):a008656. doi: 10.1101/cshperspect.a008656. Review. Erratum in: Cold Spring Harb Perspect Biol. 2015 Apr;7(4). pii: a026716. doi: 10.1101/cshperspect.a026716.


Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels.

Hesker PR, Nguyen M, Kovarova M, Ting JP, Koller BH.

PLoS One. 2012;7(11):e51105. doi: 10.1371/journal.pone.0051105. Epub 2012 Nov 30.


(-)-Epigallocatechin-3-gallate protects against NO-induced ototoxicity through the regulation of caspase- 1, caspase-3, and NF-κB activation.

Kim SJ, Lee JH, Kim BS, So HS, Park R, Myung NY, Um JY, Hong SH.

PLoS One. 2012;7(9):e43967. doi: 10.1371/journal.pone.0043967. Epub 2012 Sep 28.


Abdominal pain, arthritis, and nephrotic syndrome in a Syrian patient.

Balbo BE, Silva AA, Amaral AG, Malheiros DM, Onuchic LF, Barros RT.

Clinics (Sao Paulo). 2012;67(6):685-8. No abstract available.


Immunology in clinic review series; focus on autoinflammatory diseases: inflammasomes: mechanisms of activation.

Mankan AK, Kubarenko A, Hornung V.

Clin Exp Immunol. 2012 Mar;167(3):369-81. doi: 10.1111/j.1365-2249.2011.04534.x. Review.


Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins.

Kawai T, Akira S.

EMBO Mol Med. 2011 Sep;3(9):513-27. doi: 10.1002/emmm.201100160. Epub 2011 Aug 9. Review.


Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice.

Chae JJ, Cho YH, Lee GS, Cheng J, Liu PP, Feigenbaum L, Katz SI, Kastner DL.

Immunity. 2011 May 27;34(5):755-68. doi: 10.1016/j.immuni.2011.02.020. Epub 2011 May 19.


Renal amyloidosis in children.

Bilginer Y, Akpolat T, Ozen S.

Pediatr Nephrol. 2011 Aug;26(8):1215-27. doi: 10.1007/s00467-011-1797-x. Epub 2011 Mar 1. Review.


Increased levels of circulating Annexin A5 in Familial Mediterranean fever.

Boyajyan AS, Mkrtchyan GM, Hovhannisyan LP, Hovsepyan TJ.

J Inflamm (Lond). 2010 Nov 23;7:55. doi: 10.1186/1476-9255-7-55.


Inflammasomes and their activation.

Khare S, Luc N, Dorfleutner A, Stehlik C.

Crit Rev Immunol. 2010;30(5):463-87. Review.


Inflammatory stimuli regulate caspase substrate profiles.

Agard NJ, Maltby D, Wells JA.

Mol Cell Proteomics. 2010 May;9(5):880-93. doi: 10.1074/mcp.M900528-MCP200. Epub 2010 Feb 20.


The "other" vasculitis syndromes and kidney involvement.

Ozen S.

Pediatr Nephrol. 2010 Sep;25(9):1633-9. doi: 10.1007/s00467-009-1327-2. Epub 2009 Nov 7. Review.


Genetic variation in the familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis.

Villani AC, Lemire M, Louis E, Silverberg MS, Collette C, Fortin G, Nimmo ER, Renaud Y, Brunet S, Libioulle C, Belaiche J, Bitton A, Gaudet D, Cohen A, Langelier D, Rioux JD, Arnott ID, Wild GE, Rutgeerts P, Satsangi J, Vermeire S, Hudson TJ, Franchimont D.

PLoS One. 2009 Sep 28;4(9):e7154. doi: 10.1371/journal.pone.0007154.


Pyrin critical to macrophage IL-1beta response to Francisella challenge.

Gavrilin MA, Mitra S, Seshadri S, Nateri J, Berhe F, Hall MW, Wewers MD.

J Immunol. 2009 Jun 15;182(12):7982-9. doi: 10.4049/jimmunol.0803073.


Familial Mediterranean fever with a single MEFV mutation: where is the second hit?

Booty MG, Chae JJ, Masters SL, Remmers EF, Barham B, Le JM, Barron KS, Holland SM, Kastner DL, Aksentijevich I.

Arthritis Rheum. 2009 Jun;60(6):1851-61. doi: 10.1002/art.24569.

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