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Results: 19

1.

Strategies to modulate heritable epigenetic defects in cellular machinery: lessons from nature.

Pandian GN, Sugiyama H.

Pharmaceuticals (Basel). 2012 Dec 27;6(1):1-24. doi: 10.3390/ph6010001.

PMID:
24275784
[PubMed]
Free PMC Article
2.

Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing.

Velasquez LS, Sutherland LB, Liu Z, Grinnell F, Kamm KE, Schneider JW, Olson EN, Small EM.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16850-5. doi: 10.1073/pnas.1316764110. Epub 2013 Sep 30.

PMID:
24082095
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

SMRT-mediated co-shuttling enables export of class IIa HDACs independent of their CaM kinase phosphorylation sites.

Soriano FX, Chawla S, Skehel P, Hardingham GE.

J Neurochem. 2013 Jan;124(1):26-35. doi: 10.1111/jnc.12058. Epub 2012 Nov 15.

PMID:
23083128
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Role of Kruppel-like factor 4 in neurogenesis and radial neuronal migration in the developing cerebral cortex.

Qin S, Zhang CL.

Mol Cell Biol. 2012 Nov;32(21):4297-305. doi: 10.1128/MCB.00838-12. Epub 2012 Aug 20.

PMID:
22907754
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Coupling hippocampal neurogenesis to brain pH through proneurogenic small molecules that regulate proton sensing G protein-coupled receptors.

Schneider JW, Goetsch SC, Leng X, Ludwig SM, Russell JL, Yang CP, Zhang QJ.

ACS Chem Neurosci. 2012 Jul 18;3(7):557-68. doi: 10.1021/cn300025a. Epub 2012 Mar 14.

PMID:
22860225
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Crosstalk among Epigenetic Pathways Regulates Neurogenesis.

Jobe EM, McQuate AL, Zhao X.

Front Neurosci. 2012 May 8;6:59. doi: 10.3389/fnins.2012.00059. eCollection 2012.

PMID:
22586361
[PubMed]
Free PMC Article
7.

Histone deacetylase inhibitors in cell pluripotency, differentiation, and reprogramming.

Kretsovali A, Hadjimichael C, Charmpilas N.

Stem Cells Int. 2012;2012:184154. doi: 10.1155/2012/184154. Epub 2012 Mar 8.

PMID:
22550500
[PubMed]
Free PMC Article
8.

Functional and mechanistic exploration of an adult neurogenesis-promoting small molecule.

Petrik D, Jiang Y, Birnbaum SG, Powell CM, Kim MS, Hsieh J, Eisch AJ.

FASEB J. 2012 Aug;26(8):3148-62. doi: 10.1096/fj.11-201426. Epub 2012 Apr 27.

PMID:
22542682
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Regulated expression of pH sensing G Protein-coupled receptor-68 identified through chemical biology defines a new drug target for ischemic heart disease.

Russell JL, Goetsch SC, Aguilar HR, Coe H, Luo X, Liu N, van Rooij E, Frantz DE, Schneider JW.

ACS Chem Biol. 2012 Jun 15;7(6):1077-83. doi: 10.1021/cb300001m. Epub 2012 May 9.

PMID:
22462679
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Epigenetic (de)regulation of adult hippocampal neurogenesis: implications for depression.

Mateus-Pinheiro A, Pinto L, Sousa N.

Clin Epigenetics. 2011 Nov 1;3:5. doi: 10.1186/1868-7083-3-5.

PMID:
22414227
[PubMed]
Free PMC Article
11.

Targeting native adult heart progenitors with cardiogenic small molecules.

Russell JL, Goetsch SC, Aguilar HR, Frantz DE, Schneider JW.

ACS Chem Biol. 2012 Jun 15;7(6):1067-76. doi: 10.1021/cb200525q. Epub 2012 Apr 13.

PMID:
22413910
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A small molecule differentiation inducer increases insulin production by pancreatic β cells.

Dioum EM, Osborne JK, Goetsch S, Russell J, Schneider JW, Cobb MH.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20713-8. doi: 10.1073/pnas.1118526109. Epub 2011 Dec 5.

PMID:
22143803
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Opposing roles of voltage-gated Ca2+ channels in neuronal control of regenerative patterning.

Zhang D, Chan JD, Nogi T, Marchant JS.

J Neurosci. 2011 Nov 2;31(44):15983-95. doi: 10.1523/JNEUROSCI.3029-11.2011.

PMID:
22049441
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells.

Gao Z, Ure K, Ding P, Nashaat M, Yuan L, Ma J, Hammer RE, Hsieh J.

J Neurosci. 2011 Jun 29;31(26):9772-86. doi: 10.1523/JNEUROSCI.1604-11.2011.

PMID:
21715642
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Small-molecule blocks malignant astrocyte proliferation and induces neuronal gene expression.

Zhang L, Li P, Hsu T, Aguilar HR, Frantz DE, Schneider JW, Bachoo RM, Hsieh J.

Differentiation. 2011 Apr;81(4):233-42. doi: 10.1016/j.diff.2011.02.005. Epub 2011 Mar 17.

PMID:
21419563
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A small molecule accelerates neuronal differentiation in the adult rat.

Wurdak H, Zhu S, Min KH, Aimone L, Lairson LL, Watson J, Chopiuk G, Demas J, Charette B, Halder R, Weerapana E, Cravatt BF, Cline HT, Peters EC, Zhang J, Walker JR, Wu C, Chang J, Tuntland T, Cho CY, Schultz PG.

Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16542-7. doi: 10.1073/pnas.1010300107. Epub 2010 Sep 7. Erratum in: Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22360. Halder, Rajkumar [added].

PMID:
20823227
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells.

Luo Y, Shan G, Guo W, Smrt RD, Johnson EB, Li X, Pfeiffer RL, Szulwach KE, Duan R, Barkho BZ, Li W, Liu C, Jin P, Zhao X.

PLoS Genet. 2010 Apr 8;6(4):e1000898. doi: 10.1371/journal.pgen.1000898.

PMID:
20386739
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development.

Montgomery RL, Hsieh J, Barbosa AC, Richardson JA, Olson EN.

Proc Natl Acad Sci U S A. 2009 May 12;106(19):7876-81. doi: 10.1073/pnas.0902750106. Epub 2009 Apr 20.

PMID:
19380719
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Identification of small-molecule inducers of pancreatic beta-cell expansion.

Wang W, Walker JR, Wang X, Tremblay MS, Lee JW, Wu X, Schultz PG.

Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1427-32. doi: 10.1073/pnas.0811848106. Epub 2009 Jan 22. Erratum in: Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7264.

PMID:
19164755
[PubMed - indexed for MEDLINE]
Free PMC Article

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