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Results: 1 to 20 of 22

Cited In for PubMed (Select 18519666)


Targeting Polo-Like Kinases: A Promising Therapeutic Approach for Cancer Treatment.

Liu X.

Transl Oncol. 2015 Jun;8(3):185-95. doi: 10.1016/j.tranon.2015.03.010. Review.


Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development.

Yang H, Fang L, Zhan R, Hegarty JM, Ren J, Hsiai TK, Gleeson JG, Miller YI, Trejo J, Chi NC.

Dev Biol. 2015 Aug 15;404(2):49-60. doi: 10.1016/j.ydbio.2015.05.011. Epub 2015 May 22.


Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state.

Li Z, Li J, Bi P, Lu Y, Burcham G, Elzey BD, Ratliff T, Konieczny SF, Ahmad N, Kuang S, Liu X.

Mol Cell Biol. 2014 Oct 1;34(19):3642-61. doi: 10.1128/MCB.00814-14. Epub 2014 Jul 21.


Plk1 protein phosphorylates phosphatase and tensin homolog (PTEN) and regulates its mitotic activity during the cell cycle.

Choi BH, Pagano M, Dai W.

J Biol Chem. 2014 May 16;289(20):14066-74. doi: 10.1074/jbc.M114.558155. Epub 2014 Apr 4.


The role of polo-like kinase 1 in carcinogenesis: cause or consequence?

Cholewa BD, Liu X, Ahmad N.

Cancer Res. 2013 Dec 1;73(23):6848-55. doi: 10.1158/0008-5472.CAN-13-2197. Epub 2013 Nov 21. Review.


A novel anti-tumor inhibitor identified by virtual screen with PLK1 structure and zebrafish assay.

Lu J, Xin S, Meng H, Veldman M, Schoenfeld D, Che C, Yan R, Zhong H, Li S, Lin S.

PLoS One. 2013 Apr 26;8(4):e53317. doi: 10.1371/journal.pone.0053317. Print 2013.


Roles of Polo-like kinase 3 in suppressing tumor angiogenesis.

Xu D, Wang Q, Jiang Y, Zhang Y, Vega-Saenzdemiera E, Osman I, Dai W.

Exp Hematol Oncol. 2012 Apr 18;1(1):5. doi: 10.1186/2162-3619-1-5.


Targeting subcellular localization through the polo-box domain: non-ATP competitive inhibitors recapitulate a PLK1 phenotype.

McInnes C, Estes K, Baxter M, Yang Z, Farag DB, Johnston P, Lazo JS, Wang J, Wyatt MD.

Mol Cancer Ther. 2012 Aug;11(8):1683-92. doi: 10.1158/1535-7163.MCT-12-0006-T. Epub 2012 Jul 30.


Identification of ChIP-seq mapped targets of HP1β due to bombesin/GRP receptor activation.

Tell R, Wang QT, Blunier A, Benya RV.

Clin Epigenetics. 2011 Aug;2(2):331-8. doi: 10.1007/s13148-011-0027-5. Epub 2011 Mar 29.


Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation.

Hintermair C, Heidemann M, Koch F, Descostes N, Gut M, Gut I, Fenouil R, Ferrier P, Flatley A, Kremmer E, Chapman RD, Andrau JC, Eick D.

EMBO J. 2012 Jun 13;31(12):2784-97. doi: 10.1038/emboj.2012.123. Epub 2012 May 1.


From Plk1 to Plk5: functional evolution of polo-like kinases.

de Cárcer G, Manning G, Malumbres M.

Cell Cycle. 2011 Jul 15;10(14):2255-62. Epub 2011 Jul 15. Review.


Plk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppression.

de Cárcer G, Escobar B, Higuero AM, García L, Ansón A, Pérez G, Mollejo M, Manning G, Meléndez B, Abad-Rodríguez J, Malumbres M.

Mol Cell Biol. 2011 Mar;31(6):1225-39. doi: 10.1128/MCB.00607-10. Epub 2011 Jan 18.


Regulation of PTEN stability and activity by Plk3.

Xu D, Yao Y, Jiang X, Lu L, Dai W.

J Biol Chem. 2010 Dec 17;285(51):39935-42. doi: 10.1074/jbc.M110.166462. Epub 2010 Oct 12.


Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha.

Xu D, Yao Y, Lu L, Costa M, Dai W.

J Biol Chem. 2010 Dec 10;285(50):38944-50. doi: 10.1074/jbc.M110.160325. Epub 2010 Oct 1.


Calcium-dependent inhibition of polo-like kinase 3 activity by CIB1 in breast cancer cells.

Naik MU, Pham NT, Beebe K, Dai W, Naik UP.

Int J Cancer. 2011 Feb 1;128(3):587-96. doi: 10.1002/ijc.25388.


Polo-box domain: a versatile mediator of polo-like kinase function.

Park JE, Soung NK, Johmura Y, Kang YH, Liao C, Lee KH, Park CH, Nicklaus MC, Lee KS.

Cell Mol Life Sci. 2010 Jun;67(12):1957-70. doi: 10.1007/s00018-010-0279-9. Epub 2010 Feb 11. Review.


The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus.

Andrysik Z, Bernstein WZ, Deng L, Myer DL, Li YQ, Tischfield JA, Stambrook PJ, Bahassi el M.

Nucleic Acids Res. 2010 May;38(9):2931-43. doi: 10.1093/nar/gkq011. Epub 2010 Jan 25.


Hypoxia transiently sequesters mps1 and polo to collagenase-sensitive filaments in Drosophila prometaphase oocytes.

Gilliland WD, Vietti DL, Schweppe NM, Guo F, Johnson TJ, Hawley RS.

PLoS One. 2009 Oct 22;4(10):e7544. doi: 10.1371/journal.pone.0007544.

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