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Results: 1 to 20 of 33

1.

Ubiquitin ligases in cholesterol metabolism.

Jiang W, Song BL.

Diabetes Metab J. 2014 Jun;38(3):171-80. doi: 10.4093/dmj.2014.38.3.171. Review.

PMID:
25003069
[PubMed]
Free PMC Article
2.

The hedgehog pathway gene shifted functions together with the hmgcr-dependent isoprenoid biosynthetic pathway to orchestrate germ cell migration.

Deshpande G, Zhou K, Wan JY, Friedrich J, Jourjine N, Smith D, Schedl P.

PLoS Genet. 2013;9(9):e1003720. doi: 10.1371/journal.pgen.1003720. Epub 2013 Sep 12.

PMID:
24068944
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Deubiquitinases sharpen substrate discrimination during membrane protein degradation from the ER.

Zhang ZR, Bonifacino JS, Hegde RS.

Cell. 2013 Aug 1;154(3):609-22. doi: 10.1016/j.cell.2013.06.038. Epub 2013 Jul 25.

PMID:
23890821
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Perturbations to the ubiquitin conjugate proteome in yeast δubx mutants identify Ubx2 as a regulator of membrane lipid composition.

Kolawa N, Sweredoski MJ, Graham RL, Oania R, Hess S, Deshaies RJ.

Mol Cell Proteomics. 2013 Oct;12(10):2791-803. doi: 10.1074/mcp.M113.030163. Epub 2013 Jun 22.

PMID:
23793018
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Hepatic fatty acid and cholesterol metabolism in nephrotic syndrome.

Han S, Vaziri ND, Gollapudi P, Kwok V, Moradi H.

Am J Transl Res. 2013;5(2):246-53. Epub 2013 Mar 28.

PMID:
23573368
[PubMed]
Free PMC Article
6.

A novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) splice variant with an alternative exon 1 potentially encoding an extended N-terminus.

Stormo C, Kringen MK, Grimholt RM, Berg JP, Piehler AP.

BMC Mol Biol. 2012 Sep 18;13:29. doi: 10.1186/1471-2199-13-29.

PMID:
22989091
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Abnormal vascularization in mouse retina with dysregulated retinal cholesterol homeostasis.

Omarova S, Charvet CD, Reem RE, Mast N, Zheng W, Huang S, Peachey NS, Pikuleva IA.

J Clin Invest. 2012 Aug 1;122(8):3012-23. doi: 10.1172/JCI63816. Epub 2012 Jul 23.

PMID:
22820291
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Spatial distribution of the pathways of cholesterol homeostasis in human retina.

Zheng W, Reem RE, Omarova S, Huang S, DiPatre PL, Charvet CD, Curcio CA, Pikuleva IA.

PLoS One. 2012;7(5):e37926. doi: 10.1371/journal.pone.0037926. Epub 2012 May 22.

PMID:
22629470
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Blockade of cholesterol absorption by ezetimibe reveals a complex homeostatic network in enterocytes.

Engelking LJ, McFarlane MR, Li CK, Liang G.

J Lipid Res. 2012 Jul;53(7):1359-68. doi: 10.1194/jlr.M027599. Epub 2012 Apr 22.

PMID:
22523394
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Abnormal barrier function in the pathogenesis of ichthyosis: therapeutic implications for lipid metabolic disorders.

Elias PM, Williams ML, Feingold KR.

Clin Dermatol. 2012 May-Jun;30(3):311-22. doi: 10.1016/j.clindermatol.2011.08.017.

PMID:
22507046
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.

Jo Y, Lee PC, Sguigna PV, DeBose-Boyd RA.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20503-8. doi: 10.1073/pnas.1112831108. Epub 2011 Dec 5.

PMID:
22143767
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Indirect stimulation of human Vγ2Vδ2 T cells through alterations in isoprenoid metabolism.

Wang H, Sarikonda G, Puan KJ, Tanaka Y, Feng J, Giner JL, Cao R, Mönkkönen J, Oldfield E, Morita CT.

J Immunol. 2011 Nov 15;187(10):5099-113. doi: 10.4049/jimmunol.1002697. Epub 2011 Oct 19.

PMID:
22013129
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Regulation of HMG-CoA reductase in mammals and yeast.

Burg JS, Espenshade PJ.

Prog Lipid Res. 2011 Oct;50(4):403-10. doi: 10.1016/j.plipres.2011.07.002. Epub 2011 Jul 23. Review.

PMID:
21801748
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein.

Leichner GS, Avner R, Harats D, Roitelman J.

J Biol Chem. 2011 Sep 16;286(37):32150-61. doi: 10.1074/jbc.M111.278036. Epub 2011 Jul 21.

PMID:
21778231
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Pathogenesis of the cutaneous phenotype in inherited disorders of cholesterol metabolism: Therapeutic implications for topical treatment of these disorders.

Elias PM, Crumrine D, Paller A, Rodriguez-Martin M, Williams ML.

Dermatoendocrinol. 2011 Apr;3(2):100-6. doi: 10.4161/derm.3.2.14831. Epub 2011 Apr 1.

PMID:
21695019
[PubMed]
Free PMC Article
16.

Regulation of cholesterol and fatty acid synthesis.

Ye J, DeBose-Boyd RA.

Cold Spring Harb Perspect Biol. 2011 Jul 1;3(7). pii: a004754. doi: 10.1101/cshperspect.a004754. Review.

PMID:
21504873
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

Jo Y, Sguigna PV, DeBose-Boyd RA.

J Biol Chem. 2011 Apr 29;286(17):15022-31. doi: 10.1074/jbc.M110.211326. Epub 2011 Feb 22.

PMID:
21343306
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Quantitative role of LAL, NPC2, and NPC1 in lysosomal cholesterol processing defined by genetic and pharmacological manipulations.

Ramirez CM, Liu B, Aqul A, Taylor AM, Repa JJ, Turley SD, Dietschy JM.

J Lipid Res. 2011 Apr;52(4):688-98. doi: 10.1194/jlr.M013789. Epub 2011 Feb 2.

PMID:
21289032
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Cdc48/p97 mediates UV-dependent turnover of RNA Pol II.

Verma R, Oania R, Fang R, Smith GT, Deshaies RJ.

Mol Cell. 2011 Jan 7;41(1):82-92. doi: 10.1016/j.molcel.2010.12.017.

PMID:
21211725
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Cell cholesterol homeostasis: mediation by active cholesterol.

Steck TL, Lange Y.

Trends Cell Biol. 2010 Nov;20(11):680-7. doi: 10.1016/j.tcb.2010.08.007. Epub 2010 Sep 16. Review.

PMID:
20843692
[PubMed - indexed for MEDLINE]
Free PMC Article

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