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Items: 1 to 20 of 26

1.

An integrative genome-wide transcriptome reveals that candesartan is neuroprotective and a candidate therapeutic for Alzheimer's disease.

Elkahloun AG, Hafko R, Saavedra JM.

Alzheimers Res Ther. 2016 Jan 28;8:5. doi: 10.1186/s13195-015-0167-5.

2.

Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling.

Hu X, Fan Q, Hou H, Yan R.

J Neurochem. 2016 Jan;136(2):234-49. doi: 10.1111/jnc.13395. Epub 2015 Nov 13. Review.

PMID:
26465092
3.

Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

Bekris LM, Tsuang DW, Peskind ER, Yu CE, Montine TJ, Zhang J, Zabetian CP, Leverenz JB.

Mov Disord. 2015 Jun;30(7):936-44. doi: 10.1002/mds.26172. Epub 2015 Mar 24.

4.

Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production.

Langjahr P, Díaz-Jiménez D, De la Fuente M, Rubio E, Golenbock D, Bronfman FC, Quera R, González MJ, Hermoso MA.

PLoS One. 2014 Dec 22;9(12):e104624. doi: 10.1371/journal.pone.0104624. eCollection 2014.

5.

P2Y receptors in Alzheimer's disease.

Erb L, Cao C, Ajit D, Weisman GA.

Biol Cell. 2015 Jan;107(1):1-21. doi: 10.1111/boc.201400043. Epub 2014 Oct 13. Review.

6.

ADAM10 is the major sheddase responsible for the release of membrane-associated meprin A.

Herzog C, Haun RS, Ludwig A, Shah SV, Kaushal GP.

J Biol Chem. 2014 May 9;289(19):13308-22. doi: 10.1074/jbc.M114.559088. Epub 2014 Mar 24.

7.

Association of cerebrospinal fluid Aβ42 with A2M gene in cognitively normal subjects.

Millard SP, Lutz F, Li G, Galasko DR, Farlow MR, Quinn JF, Kaye JA, Leverenz JB, Tsuang D, Yu CE, Peskind ER, Bekris LM.

Neurobiol Aging. 2014 Feb;35(2):357-64. doi: 10.1016/j.neurobiolaging.2013.07.027. Epub 2013 Sep 4.

8.

Autism as early neurodevelopmental disorder: evidence for an sAPPα-mediated anabolic pathway.

Lahiri DK, Sokol DK, Erickson C, Ray B, Ho CY, Maloney B.

Front Cell Neurosci. 2013 Jun 21;7:94. doi: 10.3389/fncel.2013.00094. eCollection 2013.

9.

Reduction in inflammation and the expression of amyloid precursor protein and other proteins related to Alzheimer's disease following gastric bypass surgery.

Ghanim H, Monte SV, Sia CL, Abuaysheh S, Green K, Caruana JA, Dandona P.

J Clin Endocrinol Metab. 2012 Jul;97(7):E1197-201. doi: 10.1210/jc.2011-3284. Epub 2012 Apr 16.

10.

The emerging role of matrix metalloproteases of the ADAM family in male germ cell apoptosis.

Moreno RD, Urriola-Muñoz P, Lagos-Cabré R.

Spermatogenesis. 2011 Jul;1(3):195-208. Epub 2011 Jul 1.

11.

Prenatal lead levels, plasma amyloid β levels, and gene expression in young adulthood.

Mazumdar M, Xia W, Hofmann O, Gregas M, Ho Sui S, Hide W, Yang T, Needleman HL, Bellinger DC.

Environ Health Perspect. 2012 May;120(5):702-7. doi: 10.1289/ehp.1104474. Epub 2012 Feb 7.

13.

Interaction between amyloid precursor protein and Nogo receptors regulates amyloid deposition.

Zhou X, Hu X, He W, Tang X, Shi Q, Zhang Z, Yan R.

FASEB J. 2011 Sep;25(9):3146-56. doi: 10.1096/fj.11-184325. Epub 2011 Jun 13.

14.

Unsaturated fatty acids drive disintegrin and metalloproteinase (ADAM)-dependent cell adhesion, proliferation, and migration by modulating membrane fluidity.

Reiss K, Cornelsen I, Husmann M, Gimpl G, Bhakdi S.

J Biol Chem. 2011 Jul 29;286(30):26931-42. doi: 10.1074/jbc.M111.243485. Epub 2011 Jun 3.

15.

An overview of notch signaling in adult tissue renewal and maintenance.

Sato C, Zhao G, Ilagan MX.

Curr Alzheimer Res. 2012 Feb;9(2):227-40. Review.

16.

Amyloid precursor protein (APP) processing genes and cerebrospinal fluid APP cleavage product levels in Alzheimer's disease.

Bekris LM, Galloway NM, Millard S, Lockhart D, Li G, Galasko DR, Farlow MR, Clark CM, Quinn JF, Kaye JA, Schellenberg GD, Leverenz JB, Seubert P, Tsuang DW, Peskind ER, Yu CE.

Neurobiol Aging. 2011 Mar;32(3):556.e13-23. doi: 10.1016/j.neurobiolaging.2010.10.020. Epub 2010 Dec 31.

17.

Lipoprotein receptors--an evolutionarily ancient multifunctional receptor family.

Dieckmann M, Dietrich MF, Herz J.

Biol Chem. 2010 Nov;391(11):1341-63. doi: 10.1515/BC.2010.129. Review.

18.

Insulin-like growth factor-1 (IGF-1)-induced processing of amyloid-beta precursor protein (APP) and APP-like protein 2 is mediated by different metalloproteinases.

Jacobsen KT, Adlerz L, Multhaup G, Iverfeldt K.

J Biol Chem. 2010 Apr 2;285(14):10223-31. doi: 10.1074/jbc.M109.038224. Epub 2010 Feb 5.

19.

The selective beta1-adrenoceptor antagonist nebivolol is a potential oestrogen receptor agonist with neuroprotective abilities.

Manthey D, Gamerdinger M, Behl C.

Br J Pharmacol. 2010 Mar;159(6):1264-73. doi: 10.1111/j.1476-5381.2009.00610.x. Epub 2010 Feb 1.

20.

Klotho is a substrate for alpha-, beta- and gamma-secretase.

Bloch L, Sineshchekova O, Reichenbach D, Reiss K, Saftig P, Kuro-o M, Kaether C.

FEBS Lett. 2009 Oct 6;583(19):3221-4. doi: 10.1016/j.febslet.2009.09.009. Epub 2009 Sep 6.

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