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Items: 5


TEM8/ANTXR1 blockade inhibits pathological angiogenesis and potentiates tumoricidal responses against multiple cancer types.

Chaudhary A, Hilton MB, Seaman S, Haines DC, Stevenson S, Lemotte PK, Tschantz WR, Zhang XM, Saha S, Fleming T, St Croix B.

Cancer Cell. 2012 Feb 14;21(2):212-26. doi: 10.1016/j.ccr.2012.01.004.


Anthrax lethal toxin-induced gene expression changes in mouse lung.

Dumas EK, Cox PM, Fullenwider CO, Nguyen M, Centola M, Frank MB, Dozmorov I, James JA, Farris AD.

Toxins (Basel). 2011 Sep;3(9):1111-30. doi: 10.3390/toxins3091111. Epub 2011 Sep 7.


Targeting the anthrax receptors, TEM-8 and CMG-2, for anti-angiogenic therapy.

Cryan LM, Rogers MS.

Front Biosci (Landmark Ed). 2011 Jan 1;16:1574-88. Review.


The cell surface structure of tumor endothelial marker 8 (TEM8) is regulated by the actin cytoskeleton.

Yang MY, Chaudhary A, Seaman S, Dunty J, Stevens J, Elzarrad MK, Frankel AE, St Croix B.

Biochim Biophys Acta. 2011 Jan;1813(1):39-49. doi: 10.1016/j.bbamcr.2010.11.013. Epub 2010 Dec 1.


Host-derived tumor endothelial marker 8 promotes the growth of melanoma.

Cullen M, Seaman S, Chaudhary A, Yang MY, Hilton MB, Logsdon D, Haines DC, Tessarollo L, St Croix B.

Cancer Res. 2009 Aug 1;69(15):6021-6. doi: 10.1158/0008-5472.CAN-09-1086. Epub 2009 Jul 21.

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