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Results: 6

1.

Critical evaluation of vinflunine in the treatment of refractory metastatic urothelial carcinoma.

Morel A, Talbot D.

Open Access J Urol. 2010 Jun 29;2:99-108. Review.

PMID:
24198619
[PubMed]
Free PMC Article
2.

Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors.

La Regina G, Bai R, Rensen WM, Di Cesare E, Coluccia A, Piscitelli F, Famiglini V, Reggio A, Nalli M, Pelliccia S, Da Pozzo E, Costa B, Granata I, Porta A, Maresca B, Soriani A, Iannitto ML, Santoni A, Li J, Miranda Cona M, Chen F, Ni Y, Brancale A, Dondio G, Vultaggio S, Varasi M, Mercurio C, Martini C, Hamel E, Lavia P, Novellino E, Silvestri R.

J Med Chem. 2013 Jan 10;56(1):123-49. doi: 10.1021/jm3013097. Epub 2012 Dec 27.

PMID:
23214452
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Preclinical studies identify novel targeted pharmacological strategies for treatment of human malignant pleural mesothelioma.

Favoni RE, Daga A, Malatesta P, Florio T.

Br J Pharmacol. 2012 May;166(2):532-53. doi: 10.1111/j.1476-5381.2012.01873.x. Review.

PMID:
22289125
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.

La Regina G, Bai R, Rensen W, Coluccia A, Piscitelli F, Gatti V, Bolognesi A, Lavecchia A, Granata I, Porta A, Maresca B, Soriani A, Iannitto ML, Mariani M, Santoni A, Brancale A, Ferlini C, Dondio G, Varasi M, Mercurio C, Hamel E, Lavia P, Novellino E, Silvestri R.

J Med Chem. 2011 Dec 22;54(24):8394-406. doi: 10.1021/jm2012886. Epub 2011 Nov 21.

PMID:
22044164
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Design, synthesis, biological evaluation, and structure-activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4.

Fortin S, Wei L, Moreau E, Lacroix J, Côté MF, Petitclerc E, Kotra LP, C-Gaudreault R.

J Med Chem. 2011 Jul 14;54(13):4559-80. doi: 10.1021/jm200488a. Epub 2011 Jun 13.

PMID:
21604746
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies.

La Regina G, Sarkar T, Bai R, Edler MC, Saletti R, Coluccia A, Piscitelli F, Minelli L, Gatti V, Mazzoccoli C, Palermo V, Mazzoni C, Falcone C, Scovassi AI, Giansanti V, Campiglia P, Porta A, Maresca B, Hamel E, Brancale A, Novellino E, Silvestri R.

J Med Chem. 2009 Dec 10;52(23):7512-27. doi: 10.1021/jm900016t.

PMID:
19601594
[PubMed - indexed for MEDLINE]
Free PMC Article

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