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Items: 8

1.

Human neural stem cells survive long term in the midbrain of dopamine-depleted monkeys after GDNF overexpression and project neurites toward an appropriate target.

Wakeman DR, Redmond DE Jr, Dodiya HB, Sladek JR Jr, Leranth C, Teng YD, Samulski RJ, Snyder EY.

Stem Cells Transl Med. 2014 Jun;3(6):692-701. doi: 10.5966/sctm.2013-0208. Epub 2014 Apr 17.

2.

Enhancement of polysialic acid expression improves function of embryonic stem-derived dopamine neuron grafts in Parkinsonian mice.

Battista D, Ganat Y, El Maarouf A, Studer L, Rutishauser U.

Stem Cells Transl Med. 2014 Jan;3(1):108-13. doi: 10.5966/sctm.2013-0084. Epub 2013 Dec 5.

3.

Comparison of fetal mesencephalic grafts, AAV-delivered GDNF, and both combined in an MPTP-induced nonhuman primate Parkinson's model.

Redmond DE Jr, McEntire CR, Kingsbery JP, Leranth C, Elsworth JD, Bjugstad KB, Roth RH, Samulski RJ, Sladek JR Jr.

Mol Ther. 2013 Dec;21(12):2160-8. doi: 10.1038/mt.2013.180. Epub 2013 Aug 5.

4.

Transgene expression in the striatum following intracerebral injections of DNA nanoparticles encoding for human glial cell line-derived neurotrophic factor.

Fletcher AM, Kowalczyk TH, Padegimas L, Cooper MJ, Yurek DM.

Neuroscience. 2011 Oct 27;194:220-6. doi: 10.1016/j.neuroscience.2011.07.072. Epub 2011 Aug 4.

5.

Cellular repair in the parkinsonian nonhuman primate brain.

Redmond DE Jr, Weiss S, Elsworth JD, Roth RH, Wakeman DR, Bjugstad KB, Collier TJ, Blanchard BC, Teng YD, Synder EY, Sladek JR Jr.

Rejuvenation Res. 2010 Apr-Jun;13(2-3):188-94. doi: 10.1089/rej.2009.0960. Review.

6.

Viral vectors for neurotrophic factor delivery: a gene therapy approach for neurodegenerative diseases of the CNS.

Lim ST, Airavaara M, Harvey BK.

Pharmacol Res. 2010 Jan;61(1):14-26. doi: 10.1016/j.phrs.2009.10.002. Epub 2009 Oct 17. Review.

7.

Compacted DNA nanoparticle gene transfer of GDNF to the rat striatum enhances the survival of grafted fetal dopamine neurons.

Yurek DM, Flectcher AM, Kowalczyk TH, Padegimas L, Cooper MJ.

Cell Transplant. 2009;18(10):1183-96. doi: 10.3727/096368909X12483162196881. Epub 2009 Jun 22.

8.

Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF.

Redmond DE Jr, Elsworth JD, Roth RH, Leranth C, Collier TJ, Blanchard B, Bjugstad KB, Samulski RJ, Aebischer P, Sladek JR Jr.

J Comp Neurol. 2009 Jul 1;515(1):31-40. doi: 10.1002/cne.22028.

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