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Items: 1 to 20 of 27

1.

Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation.

Li J, Hardy K, Phetsouphanh C, Tu WJ, Sutcliffe EL, McCuaig R, Sutton CR, Zafar A, Munier CM, Zaunders JJ, Xu Y, Theodoratos A, Tan A, Lim PS, Knaute T, Masch A, Zerweck J, Brezar V, Milburn PJ, Dunn J, Casarotto MG, Turner SJ, Seddiki N, Kelleher AD, Rao S.

J Cell Sci. 2016 Jun 15;129(12):2448-61. doi: 10.1242/jcs.181248. Epub 2016 May 5.

2.

MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation.

Tan Y, AlKhamees B, Jia D, Li L, Couture JF, Figeys D, Jinushi M, Wang L.

Stem Cell Reports. 2015 Nov 10;5(5):741-52. doi: 10.1016/j.stemcr.2015.09.005. Epub 2015 Oct 8.

3.

The Role of PKC-θ in CD4+ T Cells and HIV Infection: To the Nucleus and Back Again.

Phetsouphanh C, Kelleher AD.

Front Immunol. 2015 Jul 30;6:391. doi: 10.3389/fimmu.2015.00391. eCollection 2015. Review.

4.

Protein kinase C in the immune system: from signalling to chromatin regulation.

Lim PS, Sutton CR, Rao S.

Immunology. 2015 Dec;146(4):508-22. doi: 10.1111/imm.12510. Epub 2015 Oct 6. Review.

PMID:
26194700
5.

Modulation of Immune Cell Functions by the E3 Ligase Cbl-b.

Lutz-Nicoladoni C, Wolf D, Sopper S.

Front Oncol. 2015 Mar 11;5:58. doi: 10.3389/fonc.2015.00058. eCollection 2015. Review.

6.

Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: involvement of protein kinase C-θ activation.

Takahashi T, Uehara H, Ogawa H, Umemoto H, Bando Y, Izumi K.

Oncotarget. 2015 Mar 10;6(7):4829-44.

7.

Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile.

Reynolds C, Chong D, Raynsford E, Quigley K, Kelly D, Llewellyn-Hughes J, Altmann D, Boyton R.

BMC Biol. 2014 May 9;12:32. doi: 10.1186/1741-7007-12-32.

8.

Reversal of global CD4+ subset dysfunction is associated with spontaneous clinical resolution of pulmonary sarcoidosis.

Oswald-Richter KA, Richmond BW, Braun NA, Isom J, Abraham S, Taylor TR, Drake JM, Culver DA, Wilkes DS, Drake WP.

J Immunol. 2013 Jun 1;190(11):5446-53. doi: 10.4049/jimmunol.1202891. Epub 2013 Apr 29.

9.

PKCα and PKCβ cooperate functionally in CD3-induced de novo IL-2 mRNA transcription.

Lutz-Nicoladoni C, Thuille N, Wachowicz K, Gruber T, Leitges M, Baier G.

Immunol Lett. 2013 Mar;151(1-2):31-8. doi: 10.1016/j.imlet.2013.02.002. Epub 2013 Feb 21. Erratum in: Immunol Lett. 2014 Jul;160(1):104. Christina, Lutz-Nicoladoni [corrected to Lutz-Nicoladoni, Christina]; Nikolaus, Thuille [corrected to Thuille, Nikolaus]; Katarzyna, Wachowicz [corrected to Wachowicz, Katarzyna]; Thomas, Gruber [corrected to Gruber, Thomas]; Michael, Leitges [corrected to Leitges, Michael]; Gottfried, Baier [corrected to Baier, Gottfried].

10.

Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality.

Sourbier C, Scroggins BT, Ratnayake R, Prince TL, Lee S, Lee MJ, Nagy PL, Lee YH, Trepel JB, Beutler JA, Linehan WM, Neckers L.

Cancer Cell. 2013 Feb 11;23(2):228-37. doi: 10.1016/j.ccr.2012.12.007. Epub 2013 Jan 23.

11.

PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes.

Thuille N, Wachowicz K, Hermann-Kleiter N, Kaminski S, Fresser F, Lutz-Nicoladoni C, Leitges M, Thome M, Massoumi R, Baier G.

PLoS One. 2013;8(1):e53709. doi: 10.1371/journal.pone.0053709. Epub 2013 Jan 15.

12.

Protein kinase C signaling and cell cycle regulation.

Black AR, Black JD.

Front Immunol. 2013 Jan 17;3:423. doi: 10.3389/fimmu.2012.00423. eCollection 2012.

13.

The emerging role of protein kinase Cθ in cytoskeletal signaling.

Michalczyk I, Sikorski AF, Kotula L, Junghans RP, Dubielecka PM.

J Leukoc Biol. 2013 Mar;93(3):319-27. doi: 10.1189/jlb.0812371. Epub 2012 Nov 27. Review.

14.

Microtubule-organizing center polarity and the immunological synapse: protein kinase C and beyond.

Huse M.

Front Immunol. 2012 Jul 31;3:235. doi: 10.3389/fimmu.2012.00235. eCollection 2012.

15.

Targeting PKCθ in alloreactivity and graft-versus-host-disease: unanswered questions and therapeutic potential.

Bronk CC, Yu XZ, Beg AA.

Front Immunol. 2012 Aug 14;3:259. doi: 10.3389/fimmu.2012.00259. eCollection 2012.

16.

Th1/Th2 Differentiation and B Cell Function by the Atypical PKCs and Their Regulators.

Martin P, Moscat J.

Front Immunol. 2012 Aug 6;3:241. doi: 10.3389/fimmu.2012.00241. eCollection 2012.

17.

Intervention of PKC-θ as an immunosuppressive regimen.

Sun Z.

Front Immunol. 2012 Aug 2;3:225. doi: 10.3389/fimmu.2012.00225. eCollection 2012.

18.

Regulating the Regulator: Phosphorylation of PKC θ in T Cells.

Freeley M, Long A.

Front Immunol. 2012 Aug 1;3:227. doi: 10.3389/fimmu.2012.00227. eCollection 2012. No abstract available.

19.

Regulation of PKC-θ function by phosphorylation in T cell receptor signaling.

Wang X, Chuang HC, Li JP, Tan TH.

Front Immunol. 2012 Jul 11;3:197. doi: 10.3389/fimmu.2012.00197. eCollection 2012.

20.

The PKCθ pathway participates in the aberrant accumulation of Fra-1 protein in invasive ER-negative breast cancer cells.

Belguise K, Milord S, Galtier F, Moquet-Torcy G, Piechaczyk M, Chalbos D.

Oncogene. 2012 Nov 22;31(47):4889-97. doi: 10.1038/onc.2011.659. Epub 2012 Jan 30.

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