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NK cell function and receptor diversity in the context of HCV infection.

Gardiner CM.

Front Microbiol. 2015 Sep 30;6:1061. doi: 10.3389/fmicb.2015.01061. eCollection 2015. Review.


A Distinctive Cytoplasmic Tail Contributes to Low Surface Expression and Intracellular Retention of the Patr-AL MHC Class I Molecule.

Goyos A, Guethlein LA, Horowitz A, Hilton HG, Gleimer M, Brodsky FM, Parham P.

J Immunol. 2015 Oct 15;195(8):3725-36. doi: 10.4049/jimmunol.1500397. Epub 2015 Sep 14.


Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes.

Hilton HG, Guethlein LA, Goyos A, Nemat-Gorgani N, Bushnell DA, Norman PJ, Parham P.

J Immunol. 2015 Oct 1;195(7):3160-70. doi: 10.4049/jimmunol.1501358. Epub 2015 Aug 26.


Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population.

Hilton HG, Norman PJ, Nemat-Gorgani N, Goyos A, Hollenbach JA, Henn BM, Gignoux CR, Guethlein LA, Parham P.

PLoS Genet. 2015 Aug 20;11(8):e1005439. doi: 10.1371/journal.pgen.1005439. eCollection 2015 Aug.


Co-evolution of MHC class I and variable NK cell receptors in placental mammals.

Guethlein LA, Norman PJ, Hilton HH, Parham P.

Immunol Rev. 2015 Sep;267(1):259-82. doi: 10.1111/imr.12326.


Can Selective MHC Downregulation Explain the Specificity and Genetic Diversity of NK Cell Receptors?

Carrillo-Bustamante P, Kesmir C, de Boer RJ.

Front Immunol. 2015 Jun 16;6:311. doi: 10.3389/fimmu.2015.00311. eCollection 2015.


The production of KIR-Fc fusion proteins and their use in a multiplex HLA class I binding assay.

Hilton HG, Moesta AK, Guethlein LA, Blokhuis J, Parham P, Norman PJ.

J Immunol Methods. 2015 Oct;425:79-87. doi: 10.1016/j.jim.2015.06.012. Epub 2015 Jun 19.


The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4.

Moradi S, Berry R, Pymm P, Hitchen C, Beckham SA, Wilce MC, Walpole NG, Clements CS, Reid HH, Perugini MA, Brooks AG, Rossjohn J, Vivian JP.

J Biol Chem. 2015 Apr 17;290(16):10460-71. doi: 10.1074/jbc.M114.612291. Epub 2015 Mar 10.


Peptide selectivity discriminates NK cells from KIR2DL2- and KIR2DL3-positive individuals.

Cassidy S, Mukherjee S, Myint TM, Mbiribindi B, North H, Traherne J, Mulder A, Claas FH, Purbhoo MA, Das J, Khakoo SI.

Eur J Immunol. 2015 Feb;45(2):492-500. doi: 10.1002/eji.201444613. Epub 2014 Nov 29.


Fine-mapping of HLA associations with chronic lymphocytic leukemia in US populations.

Gragert L, Fingerson S, Albrecht M, Maiers M, Kalaycio M, Hill BT.

Blood. 2014 Oct 23;124(17):2657-65. doi: 10.1182/blood-2014-02-558767. Epub 2014 Sep 17.


KIR diversity in Māori and Polynesians: populations in which HLA-B is not a significant KIR ligand.

Nemat-Gorgani N, Edinur HA, Hollenbach JA, Traherne JA, Dunn PP, Chambers GK, Parham P, Norman PJ.

Immunogenetics. 2014 Nov;66(11):597-611. doi: 10.1007/s00251-014-0794-1. Epub 2014 Aug 21.


Natural killer cell function and dysfunction in hepatitis C virus infection.

Holder KA, Russell RS, Grant MD.

Biomed Res Int. 2014;2014:903764. doi: 10.1155/2014/903764. Epub 2014 Jun 25. Review.


Increased frequency and function of KIR2DL1-3⁺ NK cells in primary HIV-1 infection are determined by HLA-C group haplotypes.

Körner C, Granoff ME, Amero MA, Sirignano MN, Vaidya SA, Jost S, Allen TM, Rosenberg ES, Altfeld M.

Eur J Immunol. 2014 Oct;44(10):2938-48. doi: 10.1002/eji.201444751. Epub 2014 Aug 12.


Diversity of killer cell immunoglobulin-like receptor (KIR) genotypes and KIR2DL2/3 variants in HCV treatment outcome.

Vidal-Castiñeira JR, López-Vázquez A, Martínez-Borra J, Martínez-Camblor P, Prieto J, López-Rodríguez R, Sanz-Cameno P, de la Vega J, Rodrigo L, Pérez-López R, Pérez-Álvarez R, López-Larrea C.

PLoS One. 2014 Jun 13;9(6):e99426. doi: 10.1371/journal.pone.0099426. eCollection 2014.


Activating killer cell Ig-like receptors in health and disease.

Ivarsson MA, Michaëlsson J, Fauriat C.

Front Immunol. 2014 Apr 22;5:184. doi: 10.3389/fimmu.2014.00184. eCollection 2014. Review.


Donor killer cell Ig-like receptor B haplotypes, recipient HLA-C1, and HLA-C mismatch enhance the clinical benefit of unrelated transplantation for acute myelogenous leukemia.

Cooley S, Weisdorf DJ, Guethlein LA, Klein JP, Wang T, Marsh SG, Spellman S, Haagenson MD, Saeturn K, Ladner M, Trachtenberg E, Parham P, Miller JS.

J Immunol. 2014 May 15;192(10):4592-600. doi: 10.4049/jimmunol.1302517. Epub 2014 Apr 18.


Effects of Peptide on NK cell-mediated MHC I recognition.

Cassidy SA, Cheent KS, Khakoo SI.

Front Immunol. 2014 Mar 31;5:133. doi: 10.3389/fimmu.2014.00133. eCollection 2014. Review.


Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity at KIR2DL2/KIR2DL3.

Roberts CH, Molina S, Makalo P, Joof H, Harding-Esch EM, Burr SE, Mabey DC, Bailey RL, Burton MJ, Holland MJ.

PLoS Negl Trop Dis. 2014 Mar 20;8(3):e2744. doi: 10.1371/journal.pntd.0002744. eCollection 2014 Mar.


Current and Potential Uses of Immunocytokines as Cancer Immunotherapy.

Sondel PM, Gillies SD.

Antibodies (Basel). 2012 Jul 4;1(2):149-171.


Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity.

O'Connor GM, Vivian JP, Widjaja JM, Bridgeman JS, Gostick E, Lafont BA, Anderson SK, Price DA, Brooks AG, Rossjohn J, McVicar DW.

J Immunol. 2014 Mar 15;192(6):2875-84. doi: 10.4049/jimmunol.1303142. Epub 2014 Feb 21.

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