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Items: 1 to 20 of 192


Polymorphisms of Insulin-Like Growth Factor 1 Pathway Genes and Breast Cancer Risk.

Shi J, Aronson KJ, Grundy A, Kobayashi LC, Burstyn I, Schuetz JM, Lohrisch CA, SenGupta SK, Lai AS, Brooks-Wilson A, Spinelli JJ, Richardson H.

Front Oncol. 2016 Jun 8;6:136. doi: 10.3389/fonc.2016.00136. eCollection 2016.


The Somatotropic Axis in Human Aging: Framework for the Current State of Knowledge and Future Research.

Milman S, Huffman DM, Barzilai N.

Cell Metab. 2016 Jun 14;23(6):980-9. doi: 10.1016/j.cmet.2016.05.014. Review.


Association between Cognition and Serum Insulin-Like Growth Factor-1 in Middle-Aged & Older Men: An 8 Year Follow-Up Study.

Tumati S, Burger H, Martens S, van der Schouw YT, Aleman A.

PLoS One. 2016 Apr 26;11(4):e0154450. doi: 10.1371/journal.pone.0154450. eCollection 2016.


Whole-Genome Sequencing of a Healthy Aging Cohort.

Erikson GA, Bodian DL, Rueda M, Molparia B, Scott ER, Scott-Van Zeeland AA, Topol SE, Wineinger NE, Niederhuber JE, Topol EJ, Torkamani A.

Cell. 2016 May 5;165(4):1002-11. doi: 10.1016/j.cell.2016.03.022. Epub 2016 Apr 21.


A Human Variant of Glucose-Regulated Protein 94 That Inefficiently Supports IGF Production.

Marzec M, Hawkes CP, Eletto D, Boyle S, Rosenfeld R, Hwa V, Wit JM, van Duyvenvoorde HA, Oostdijk W, Losekoot M, Pedersen O, Yeap BB, Flicker L, Barzilai N, Atzmon G, Grimberg A, Argon Y.

Endocrinology. 2016 May;157(5):1914-28. doi: 10.1210/en.2015-2058. Epub 2016 Mar 16.


Genetic landscape of APOE in human longevity revealed by high-throughput sequencing.

Ryu S, Atzmon G, Barzilai N, Raghavachari N, Suh Y.

Mech Ageing Dev. 2016 Apr;155:7-9. doi: 10.1016/j.mad.2016.02.010. Epub 2016 Feb 27.


The somatotropic axis and aging: Benefits of endocrine defects.

Bartke A, List EO, Kopchick JJ.

Growth Horm IGF Res. 2016 Apr;27:41-5. doi: 10.1016/j.ghir.2016.02.002. Epub 2016 Feb 16. Review.


NADPH oxidases: key modulators in aging and age-related cardiovascular diseases?

Sahoo S, Meijles DN, Pagano PJ.

Clin Sci (Lond). 2016 Mar;130(5):317-35. doi: 10.1042/CS20150087. Review.


IGF-1 Receptor Differentially Regulates Spontaneous and Evoked Transmission via Mitochondria at Hippocampal Synapses.

Gazit N, Vertkin I, Shapira I, Helm M, Slomowitz E, Sheiba M, Mor Y, Rizzoli S, Slutsky I.

Neuron. 2016 Feb 3;89(3):583-97. doi: 10.1016/j.neuron.2015.12.034. Epub 2016 Jan 21.


Growth hormone actions during development influence adult phenotype and longevity.

Bartke A, Sun L, Fang Y, Hill C.

Exp Gerontol. 2016 Jan 2. pii: S0531-5565(15)30109-1. doi: 10.1016/j.exger.2015.12.011. [Epub ahead of print]


Association study of polymorphisms in FOXO3, AKT1 and IGF-2R genes with human longevity in a Han Chinese population.

Li N, Luo H, Liu X, Ma S, Lin H, Chen R, Hao F, Zhang D.

Oncotarget. 2016 Jan 5;7(1):23-32. doi: 10.18632/oncotarget.6627.


Long live FOXO: unraveling the role of FOXO proteins in aging and longevity.

Martins R, Lithgow GJ, Link W.

Aging Cell. 2016 Apr;15(2):196-207. doi: 10.1111/acel.12427. Epub 2015 Dec 8. Review.


The African Turquoise Killifish Genome Provides Insights into Evolution and Genetic Architecture of Lifespan.

Valenzano DR, Benayoun BA, Singh PP, Zhang E, Etter PD, Hu CK, Clément-Ziza M, Willemsen D, Cui R, Harel I, Machado BE, Yee MC, Sharp SC, Bustamante CD, Beyer A, Johnson EA, Brunet A.

Cell. 2015 Dec 3;163(6):1539-54. doi: 10.1016/j.cell.2015.11.008.


Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study.

van der Spoel E, Rozing MP, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, de Craen AJ, Westendorp RG, van Heemst D.

Aging (Albany NY). 2015 Nov;7(11):956-63.


Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline.

Huffman DM, Farias Quipildor G, Mao K, Zhang X, Wan J, Apontes P, Cohen P, Barzilai N.

Aging Cell. 2016 Feb;15(1):181-6. doi: 10.1111/acel.12415. Epub 2015 Nov 4.


Mini-review: Retarding aging in murine genetic models of neurodegeneration.

Albin RL, Miller RA.

Neurobiol Dis. 2016 Jan;85:73-80. doi: 10.1016/j.nbd.2015.10.014. Epub 2015 Oct 21. Review.


Growth Hormone Receptor Antagonist Transgenic Mice Have Increased Subcutaneous Adipose Tissue Mass, Altered Glucose Homeostasis and No Change in White Adipose Tissue Cellular Senescence.

Comisford R, Lubbers ER, Householder LA, Suer O, Tchkonia T, Kirkland JL, List EO, Kopchick JJ, Berryman DE.

Gerontology. 2016;62(2):163-72. doi: 10.1159/000439050. Epub 2015 Sep 16.


A Genetic Network Associated With Stress Resistance, Longevity, and Cancer in Humans.

Levine ME, Crimmins EM.

J Gerontol A Biol Sci Med Sci. 2016 Jun;71(6):703-12. doi: 10.1093/gerona/glv141. Epub 2015 Sep 9.


Longevity: Mapping the path to a longer life.

White MF.

Nature. 2015 Aug 13;524(7564):170-1. doi: 10.1038/524170a. No abstract available.


The somatotropic axis and longevity in mice.

Brown-Borg HM.

Am J Physiol Endocrinol Metab. 2015 Sep 15;309(6):E503-10. doi: 10.1152/ajpendo.00262.2015. Epub 2015 Jul 28. Review.

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