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Processing and transcriptome expansion at the mRNA 3' end in health and disease: finding the right end.

Ogorodnikov A, Kargapolova Y, Danckwardt S.

Pflugers Arch. 2016 Jun;468(6):993-1012. doi: 10.1007/s00424-016-1828-3. Epub 2016 May 25. Review.


Alternative Polyadenylation of mRNAs: 3'-Untranslated Region Matters in Gene Expression.

Yeh HS, Yong J.

Mol Cells. 2016 Apr 30;39(4):281-5. doi: 10.14348/molcells.2016.0035. Epub 2016 Feb 25. Review.


Embryonic Stem Cells Exhibit mRNA Isoform Specific Translational Regulation.

Wong QW, Vaz C, Lee QY, Zhao TY, Luo R, Archer SK, Preiss T, Tanavde V, Vardy LA.

PLoS One. 2016 Jan 22;11(1):e0143235. doi: 10.1371/journal.pone.0143235. eCollection 2016.


Seed Dormancy in Arabidopsis Is Controlled by Alternative Polyadenylation of DOG1.

Cyrek M, Fedak H, Ciesielski A, Guo Y, Sliwa A, Brzezniak L, Krzyczmonik K, Pietras Z, Kaczanowski S, Liu F, Swiezewski S.

Plant Physiol. 2016 Feb;170(2):947-55. doi: 10.1104/pp.15.01483. Epub 2015 Nov 30.


RAX2: a genome-wide detection method of condition-associated transcription variation.

Tan YD, Deng J, Neilson JR.

Nucleic Acids Res. 2015 Sep 3;43(15):e96. doi: 10.1093/nar/gkv411. Epub 2015 May 7.


The 3' end prothrombin gene variants in serbian patients with idiopathic thrombophilia.

Aradjanski M, Djordjevic V, Pruner I, Tomic B, Gvozdenov M, Kovac M, Radojkovic D.

Balkan J Med Genet. 2015 Apr 10;17(2):43-8. doi: 10.2478/bjmg-2014-0073. eCollection 2014 Dec.


Poly(A) Polymerase and the Nuclear Poly(A) Binding Protein, PABPN1, Coordinate the Splicing and Degradation of a Subset of Human Pre-mRNAs.

Muniz L, Davidson L, West S.

Mol Cell Biol. 2015 Jul;35(13):2218-30. doi: 10.1128/MCB.00123-15. Epub 2015 Apr 20.


Ribonucleic acid (RNA) biosynthesis in human cancer.

Hajjawi OS.

Cancer Cell Int. 2015 Feb 21;15:22. doi: 10.1186/s12935-015-0167-3. eCollection 2015.


CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3' processing.

Chan SL, Huppertz I, Yao C, Weng L, Moresco JJ, Yates JR 3rd, Ule J, Manley JL, Shi Y.

Genes Dev. 2014 Nov 1;28(21):2370-80. doi: 10.1101/gad.250993.114. Epub 2014 Oct 9.


Loss of MBNL leads to disruption of developmentally regulated alternative polyadenylation in RNA-mediated disease.

Batra R, Charizanis K, Manchanda M, Mohan A, Li M, Finn DJ, Goodwin M, Zhang C, Sobczak K, Thornton CA, Swanson MS.

Mol Cell. 2014 Oct 23;56(2):311-22. doi: 10.1016/j.molcel.2014.08.027. Epub 2014 Sep 25.


U2 snRNP is required for expression of the 3' end of genes.

Koga M, Satoh T, Takasaki I, Kawamura Y, Yoshida M, Kaida D.

PLoS One. 2014 May 20;9(5):e98015. doi: 10.1371/journal.pone.0098015. eCollection 2014.


RNA sequencing: from tag-based profiling to resolving complete transcript structure.

de Klerk E, den Dunnen JT, 't Hoen PA.

Cell Mol Life Sci. 2014 Sep;71(18):3537-51. doi: 10.1007/s00018-014-1637-9. Epub 2014 May 15. Review.


The polyadenylation code: a unified model for the regulation of mRNA alternative polyadenylation.

Davis R, Shi Y.

J Zhejiang Univ Sci B. 2014 May;15(5):429-37. doi: 10.1631/jzus.B1400076. Review.


Alternative polyadenylation of tumor suppressor genes in small intestinal neuroendocrine tumors.

Rehfeld A, Plass M, Døssing K, Knigge U, Kjær A, Krogh A, Friis-Hansen L.

Front Endocrinol (Lausanne). 2014 Apr 15;5:46. doi: 10.3389/fendo.2014.00046. eCollection 2014.


Delineating the structural blueprint of the pre-mRNA 3'-end processing machinery.

Xiang K, Tong L, Manley JL.

Mol Cell Biol. 2014 Jun;34(11):1894-910. doi: 10.1128/MCB.00084-14. Epub 2014 Mar 3. Review.


Integrin α3β1 controls mRNA splicing that determines Cox-2 mRNA stability in breast cancer cells.

Subbaram S, Lyons SP, Svenson KB, Hammond SL, McCabe LG, Chittur SV, DiPersio CM.

J Cell Sci. 2014 Mar 15;127(Pt 6):1179-89. doi: 10.1242/jcs.131227. Epub 2014 Jan 16.


mRNA 3'end processing: A tale of the tail reaches the clinic.

Hollerer I, Grund K, Hentze MW, Kulozik AE.

EMBO Mol Med. 2014 Jan;6(1):16-26. doi: 10.1002/emmm.201303300. Review.


The nucleosome regulates the usage of polyadenylation sites in the human genome.

Huang H, Chen J, Liu H, Sun X.

BMC Genomics. 2013 Dec 23;14:912. doi: 10.1186/1471-2164-14-912.


Means to an end: mechanisms of alternative polyadenylation of messenger RNA precursors.

Gruber AR, Martin G, Keller W, Zavolan M.

Wiley Interdiscip Rev RNA. 2014 Mar-Apr;5(2):183-96. doi: 10.1002/wrna.1206. Epub 2013 Nov 14. Review.


Overlapping and distinct functions of CstF64 and CstF64τ in mammalian mRNA 3' processing.

Yao C, Choi EA, Weng L, Xie X, Wan J, Xing Y, Moresco JJ, Tu PG, Yates JR 3rd, Shi Y.

RNA. 2013 Dec;19(12):1781-90. doi: 10.1261/rna.042317.113. Epub 2013 Oct 22.

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