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Items: 8

1.

RAC1 activation drives pathologic interactions between the epidermis and immune cells.

Winge MC, Ohyama B, Dey CN, Boxer LM, Li W, Ehsani-Chimeh N, Truong AK, Wu D, Armstrong AW, Makino T, Davidson M, Starcevic D, Kislat A, Nguyen NT, Hashimoto T, Homey B, Khavari PA, Bradley M, Waterman EA, Marinkovich MP.

J Clin Invest. 2016 Jul 1;126(7):2661-77. doi: 10.1172/JCI85738. Epub 2016 Jun 13.

PMID:
27294528
2.

ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.

Boxer LD, Barajas B, Tao S, Zhang J, Khavari PA.

Genes Dev. 2014 Sep 15;28(18):2013-26. doi: 10.1101/gad.246579.114.

3.

Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms.

Li B, Tsoi LC, Swindell WR, Gudjonsson JE, Tejasvi T, Johnston A, Ding J, Stuart PE, Xing X, Kochkodan JJ, Voorhees JJ, Kang HM, Nair RP, Abecasis GR, Elder JT.

J Invest Dermatol. 2014 Jul;134(7):1828-38. doi: 10.1038/jid.2014.28. Epub 2014 Jan 17.

4.

Common variants of ZNF750, RPTOR and TRAF3IP2 genes and psoriasis risk.

Dębniak T, Soczawa E, Boer M, Różewicka-Czabańska M, Wiśniewska J, Serrano-Fernandez P, Mirecka A, Paszkowska-Szczur K, Lubinski J, Krysztoforska L, Adamski Z, Maleszka R.

Arch Dermatol Res. 2014 Apr;306(3):231-8. doi: 10.1007/s00403-013-1407-9. Epub 2013 Sep 5.

5.

Genomic profiling of a human organotypic model of AEC syndrome reveals ZNF750 as an essential downstream target of mutant TP63.

Zarnegar BJ, Webster DE, Lopez-Pajares V, Vander Stoep Hunt B, Qu K, Yan KJ, Berk DR, Sen GL, Khavari PA.

Am J Hum Genet. 2012 Sep 7;91(3):435-43. doi: 10.1016/j.ajhg.2012.07.007. Epub 2012 Aug 23.

6.

PSORS2 is due to mutations in CARD14.

Jordan CT, Cao L, Roberson ED, Pierson KC, Yang CF, Joyce CE, Ryan C, Duan S, Helms CA, Liu Y, Chen Y, McBride AA, Hwu WL, Wu JY, Chen YT, Menter A, Goldbach-Mansky R, Lowes MA, Bowcock AM.

Am J Hum Genet. 2012 May 4;90(5):784-95. doi: 10.1016/j.ajhg.2012.03.012. Epub 2012 Apr 19.

7.

ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation.

Sen GL, Boxer LD, Webster DE, Bussat RT, Qu K, Zarnegar BJ, Johnston D, Siprashvili Z, Khavari PA.

Dev Cell. 2012 Mar 13;22(3):669-77. doi: 10.1016/j.devcel.2011.12.001. Epub 2012 Feb 23.

8.

Association analysis identifies ZNF750 regulatory variants in psoriasis.

Birnbaum RY, Hayashi G, Cohen I, Poon A, Chen H, Lam ET, Kwok PY, Birk OS, Liao W.

BMC Med Genet. 2011 Dec 20;12:167. doi: 10.1186/1471-2350-12-167.

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