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Contribution of ENPP1, TCF7L2, and FTO polymorphisms to type 2 diabetes in mixed ancestry ethnic population of South Africa.

Yako YY, Madubedube JH, Kengne AP, Erasmus RT, Pillay TS, Matsha TE.

Afr Health Sci. 2015 Dec;15(4):1149-60. doi: 10.4314/ahs.v15i4.14.


The neuropilin-like protein ESDN regulates insulin signaling and sensitivity.

Li X, Jung JJ, Nie L, Razavian M, Zhang J, Samuel V, Sadeghi MM.

Am J Physiol Heart Circ Physiol. 2016 May 1;310(9):H1184-93. doi: 10.1152/ajpheart.00782.2015. Epub 2016 Feb 26.


Proteomic Analysis of Disease Stratified Human Pancreas Tissue Indicates Unique Signature of Type 1 Diabetes.

Burch TC, Morris MA, Campbell-Thompson M, Pugliese A, Nadler JL, Nyalwidhe JO.

PLoS One. 2015 Aug 24;10(8):e0135663. doi: 10.1371/journal.pone.0135663. eCollection 2015.


A unified model for bone-renal mineral and energy metabolism.

Rowe PS.

Curr Opin Pharmacol. 2015 Jun;22:64-71. doi: 10.1016/j.coph.2015.03.006. Epub 2015 Apr 13. Review.


Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans.

Todd JN, Poon W, Lyssenko V, Groop L, Nichols B, Wilmot M, Robson S, Enjyoji K, Herman MA, Hu C, Zhang R, Jia W, Ma R, Florez JC, Friedman DJ.

J Clin Endocrinol Metab. 2015 May;100(5):E688-96. doi: 10.1210/jc.2014-4160. Epub 2015 Feb 26.


Deficiency of the bone mineralization inhibitor NPP1 protects mice against obesity and diabetes.

Huesa C, Zhu D, Glover JD, Ferron M, Karsenty G, Milne EM, Millan JL, Ahmed SF, Farquharson C, Morton NM, MacRae VE.

Dis Model Mech. 2014 Dec;7(12):1341-50. doi: 10.1242/dmm.017905. Epub 2014 Oct 31.


Insulin resistance induced by hyperinsulinemia coincides with a persistent alteration at the insulin receptor tyrosine kinase domain.

Catalano KJ, Maddux BA, Szary J, Youngren JF, Goldfine ID, Schaufele F.

PLoS One. 2014 Sep 26;9(9):e108693. doi: 10.1371/journal.pone.0108693. eCollection 2014.


PHEX mimetic (SPR4-peptide) corrects and improves HYP and wild type mice energy-metabolism.

Zelenchuk LV, Hedge AM, Rowe PS.

PLoS One. 2014 May 19;9(5):e97326. doi: 10.1371/journal.pone.0097326. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e101192.


Vascular calcification is dependent on plasma levels of pyrophosphate.

Lomashvili KA, Narisawa S, Millán JL, O'Neill WC.

Kidney Int. 2014 Jun;85(6):1351-6. doi: 10.1038/ki.2013.521. Epub 2014 Apr 9.


Intersection of complex genetic traits affecting maternal metabolism, fetal metabolism, and neural tube defect risk: looking for needles in multiple haystacks.

Loeken MR.

Mol Genet Metab. 2014 Apr;111(4):415-7. doi: 10.1016/j.ymgme.2014.01.010. Epub 2014 Jan 25. No abstract available.


Maternal-fetal metabolic gene-gene interactions and risk of neural tube defects.

Lupo PJ, Mitchell LE, Canfield MA, Shaw GM, Olshan AF, Finnell RH, Zhu H; National Birth Defects Prevention Study.

Mol Genet Metab. 2014 Jan;111(1):46-51. doi: 10.1016/j.ymgme.2013.11.004. Epub 2013 Nov 18.


Cole Disease Results from Mutations in ENPP1.

Eytan O, Morice-Picard F, Sarig O, Ezzedine K, Isakov O, Li Q, Ishida-Yamamoto A, Shomron N, Goldsmith T, Fuchs-Telem D, Adir N, Uitto J, Orlow SJ, Taieb A, Sprecher E.

Am J Hum Genet. 2013 Oct 3;93(4):752-7. doi: 10.1016/j.ajhg.2013.08.007. Epub 2013 Sep 26.


Spatio-temporal analysis of type 2 diabetes mellitus based on differential expression networks.

Sun SY, Liu ZP, Zeng T, Wang Y, Chen L.

Sci Rep. 2013;3:2268. doi: 10.1038/srep02268.


Enpp1: a potential facilitator of breast cancer bone metastasis.

Lau WM, Doucet M, Stadel R, Huang D, Weber KL, Kominsky SL.

PLoS One. 2013 Jul 5;8(7):e66752. doi: 10.1371/journal.pone.0066752. Print 2013.


Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in mice.

Goldsworthy M, Absalom NL, Schröter D, Matthews HC, Bogani D, Moir L, Long A, Church C, Hugill A, Anstee QM, Goldin R, Thursz M, Hollfelder F, Cox RD.

PLoS One. 2013 Jun 24;8(6):e61870. doi: 10.1371/journal.pone.0061870. Print 2013.


Variants of insulin-signaling inhibitor genes in type 2 diabetes and related metabolic abnormalities.

de Lorenzo C, Greco A, Fiorentino TV, Mannino GC, Hribal ML.

Int J Genomics. 2013;2013:376454. doi: 10.1155/2013/376454. Epub 2013 May 23.


Aging and insulin resistance: just say iNOS.

Evans JL, Goldfine ID.

Diabetes. 2013 Feb;62(2):346-8. doi: 10.2337/db12-1239. No abstract available.


Adipose tissue dysfunction in humans: a potential role for the transmembrane protein ENPP1.

Chandalia M, Davila H, Pan W, Szuszkiewicz M, Tuvdendorj D, Livingston EH, Abate N.

J Clin Endocrinol Metab. 2012 Dec;97(12):4663-72. doi: 10.1210/jc.2012-2018. Epub 2012 Sep 25.


Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances.

Siddle K.

Front Endocrinol (Lausanne). 2012 Feb 28;3:34. doi: 10.3389/fendo.2012.00034. eCollection 2012.


The mammalian tribbles homolog TRIB3, glucose homeostasis, and cardiovascular diseases.

Prudente S, Sesti G, Pandolfi A, Andreozzi F, Consoli A, Trischitta V.

Endocr Rev. 2012 Aug;33(4):526-46. doi: 10.1210/er.2011-1042. Epub 2012 May 10. Review.

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