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Results: 1 to 20 of 29

1.

Dual inhibition of EGFR at protein and activity level via combinatorial blocking of PI4KIIα as anti-tumor strategy.

Li J, Zhang L, Gao Z, Kang H, Rong G, Zhang X, Chen C.

Protein Cell. 2014 Jun;5(6):457-68. doi: 10.1007/s13238-014-0055-y. Epub 2014 May 7.

PMID:
24801752
[PubMed - in process]
Free PMC Article
2.

Inhibiting heat shock factor 1 in human cancer cells with a potent RNA aptamer.

Salamanca HH, Antonyak MA, Cerione RA, Shi H, Lis JT.

PLoS One. 2014 May 6;9(5):e96330. doi: 10.1371/journal.pone.0096330. eCollection 2014.

PMID:
24800749
[PubMed - in process]
Free PMC Article
3.

Expression of heat shock protein (Hsp90) paralogues is regulated by amino acids in skeletal muscle of Atlantic salmon.

Garcia de la Serrana D, Johnston IA.

PLoS One. 2013 Sep 6;8(9):e74295. doi: 10.1371/journal.pone.0074295. eCollection 2013.

PMID:
24040223
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Combined delivery of paclitaxel and tanespimycin via micellar nanocarriers: pharmacokinetics, efficacy and metabolomic analysis.

Katragadda U, Fan W, Wang Y, Teng Q, Tan C.

PLoS One. 2013;8(3):e58619. doi: 10.1371/journal.pone.0058619. Epub 2013 Mar 7.

PMID:
23505544
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Wild-type EGFR is stabilized by direct interaction with HSP90 in cancer cells and tumors.

Ahsan A, Ramanand SG, Whitehead C, Hiniker SM, Rehemtulla A, Pratt WB, Jolly S, Gouveia C, Truong K, Van Waes C, Ray D, Lawrence TS, Nyati MK.

Neoplasia. 2012 Aug;14(8):670-7.

PMID:
22952420
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A high-content biosensor-based screen identifies cell-permeable activators and inhibitors of EGFR function: implications in drug discovery.

Antczak C, Mahida JP, Bhinder B, Calder PA, Djaballah H.

J Biomol Screen. 2012 Aug;17(7):885-99. doi: 10.1177/1087057112446174. Epub 2012 May 9.

PMID:
22573732
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Pharmacokinetic study of 3-in-1 poly(ethylene glycol)-block-poly(D, L-lactic acid) micelles carrying paclitaxel, 17-allylamino-17-demethoxygeldanamycin, and rapamycin.

Shin HC, Cho H, Lai TC, Kozak KR, Kolesar JM, Kwon GS.

J Control Release. 2012 Oct 10;163(1):93-9. doi: 10.1016/j.jconrel.2012.04.024. Epub 2012 Apr 23.

PMID:
22549011
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33.

Azoitei N, Hoffmann CM, Ellegast JM, Ball CR, Obermayer K, Gößele U, Koch B, Faber K, Genze F, Schrader M, Kestler HA, Döhner H, Chiosis G, Glimm H, Fröhling S, Scholl C.

J Exp Med. 2012 Apr 9;209(4):697-711. doi: 10.1084/jem.20111910. Epub 2012 Mar 26.

PMID:
22451720
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Noncovalent assembly of targeted carbon nanovectors enables synergistic drug and radiation cancer therapy in vivo.

Sano D, Berlin JM, Pham TT, Marcano DC, Valdecanas DR, Zhou G, Milas L, Myers JN, Tour JM.

ACS Nano. 2012 Mar 27;6(3):2497-505. doi: 10.1021/nn204885f. Epub 2012 Feb 16.

PMID:
22316245
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Synergistic activity of the Hsp90 inhibitor ganetespib with taxanes in non-small cell lung cancer models.

Proia DA, Sang J, He S, Smith DL, Sequeira M, Zhang C, Liu Y, Ye S, Zhou D, Blackman RK, Foley KP, Koya K, Wada Y.

Invest New Drugs. 2012 Dec;30(6):2201-9. doi: 10.1007/s10637-011-9790-6. Epub 2012 Jan 10.

PMID:
22227828
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Hsp90 molecular chaperone inhibitors: are we there yet?

Neckers L, Workman P.

Clin Cancer Res. 2012 Jan 1;18(1):64-76. doi: 10.1158/1078-0432.CCR-11-1000. Review.

PMID:
22215907
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Concomitant inhibition of HSP90, its mitochondrial localized homologue TRAP1 and HSP27 by green tea in pancreatic cancer HPAF-II cells.

Zhang L, Pang E, Loo RR, Rao J, Go VL, Loo JA, Lu QY.

Proteomics. 2011 Dec;11(24):4638-47. doi: 10.1002/pmic.201100242. Epub 2011 Nov 23.

PMID:
22116673
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Curcumin induces EGFR degradation in lung adenocarcinoma and modulates p38 activation in intestine: the versatile adjuvant for gefitinib therapy.

Lee JY, Lee YM, Chang GC, Yu SL, Hsieh WY, Chen JJ, Chen HW, Yang PC.

PLoS One. 2011;6(8):e23756. doi: 10.1371/journal.pone.0023756. Epub 2011 Aug 17.

PMID:
21858220
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Multi-drug delivery to tumor cells via micellar nanocarriers.

Katragadda U, Teng Q, Rayaprolu BM, Chandran T, Tan C.

Int J Pharm. 2011 Oct 31;419(1-2):281-6. doi: 10.1016/j.ijpharm.2011.07.033. Epub 2011 Jul 27.

PMID:
21820041
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

New strategies in overcoming acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer.

Oxnard GR, Arcila ME, Chmielecki J, Ladanyi M, Miller VA, Pao W.

Clin Cancer Res. 2011 Sep 1;17(17):5530-7. doi: 10.1158/1078-0432.CCR-10-2571. Epub 2011 Jul 20. Review.

PMID:
21775534
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

An RNA aptamer perturbs heat shock transcription factor activity in Drosophila melanogaster.

Salamanca HH, Fuda N, Shi H, Lis JT.

Nucleic Acids Res. 2011 Aug;39(15):6729-40. doi: 10.1093/nar/gkr206. Epub 2011 May 16.

PMID:
21576228
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Lung cancer in never smokers.

Yang P.

Semin Respir Crit Care Med. 2011 Feb;32(1):10-21. doi: 10.1055/s-0031-1272865. Epub 2011 Apr 15. Review.

PMID:
21500120
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Expression-based in silico screening of candidate therapeutic compounds for lung adenocarcinoma.

Wang G, Ye Y, Yang X, Liao H, Zhao C, Liang S.

PLoS One. 2011 Jan 21;6(1):e14573. doi: 10.1371/journal.pone.0014573.

PMID:
21283735
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Antitumor activity of SNX-2112, a synthetic heat shock protein-90 inhibitor, in MET-amplified tumor cells with or without resistance to selective MET Inhibition.

Bachleitner-Hofmann T, Sun MY, Chen CT, Liska D, Zeng Z, Viale A, Olshen AB, Mittlboeck M, Christensen JG, Rosen N, Solit DB, Weiser MR.

Clin Cancer Res. 2011 Jan 1;17(1):122-33. doi: 10.1158/1078-0432.CCR-10-0253.

PMID:
21208906
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

EGFR-mutated lung cancer: a paradigm of molecular oncology.

Zhang Z, Stiegler AL, Boggon TJ, Kobayashi S, Halmos B.

Oncotarget. 2010 Nov;1(7):497-514. Review.

PMID:
21165163
[PubMed - indexed for MEDLINE]
Free PMC Article

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