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Afatinib down-regulates MCL-1 expression through the PERK-eIF2α-ATF4 axis and leads to apoptosis in head and neck squamous cell carcinoma.

Liu X, Lv Z, Zou J, Liu X, Ma J, Wang J, Sa N, Jing P, Xu W.

Am J Cancer Res. 2016 Aug 1;6(8):1708-19. eCollection 2016.


Chloride channel protein 2 prevents glutamate-induced apoptosis in retinal ganglion cells.

Bi MM, Hong S, Ma LJ, Zhou HY, Lu J, Zhao J, Zheng YJ.

Iran J Basic Med Sci. 2016 Jul;19(7):705-11.


Oncogenic Mutations Differentially Affect Bax Monomer, Dimer, and Oligomeric Pore Formation in the Membrane.

Zhang M, Zheng J, Nussinov R, Ma B.

Sci Rep. 2016 Sep 15;6:33340. doi: 10.1038/srep33340.


The pharmacogenomics of drug resistance to protein kinase inhibitors.

Gillis NK, McLeod HL.

Drug Resist Updat. 2016 Sep;28:28-42. doi: 10.1016/j.drup.2016.06.008. Epub 2016 Jul 5.


The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation.

Lauterwasser J, Todt F, Zerbes RM, Nguyen TN, Craigen W, Lazarou M, van der Laan M, Edlich F.

Sci Rep. 2016 Sep 13;6:32994. doi: 10.1038/srep32994.


Modulation of Bcl-x Alternative Splicing Induces Apoptosis of Human Hepatic Stellate Cells.

Wu L, Mao C, Ming X.

Biomed Res Int. 2016;2016:7478650. doi: 10.1155/2016/7478650. Epub 2016 Aug 7.


MicroRNA-184 Promotes Proliferation and Inhibits Apoptosis in HaCaT Cells: An In Vitro Study.

Bi X, Cao Y, Chen R, Liu C, Chen J, Min D.

Med Sci Monit. 2016 Aug 29;22:3056-61.


Expression levels of the BAK1 and BCL2 genes highlight the role of apoptosis in age-related hearing impairment.

Falah M, Najafi M, Houshmand M, Farhadi M.

Clin Interv Aging. 2016 Jul 28;11:1003-8. doi: 10.2147/CIA.S109110. eCollection 2016.


Benzo(a)pyrene Induced p53 Mediated Male Germ Cell Apoptosis: Synergistic Protective Effects of Curcumin and Resveratrol.

Banerjee B, Chakraborty S, Ghosh D, Raha S, Sen PC, Jana K.

Front Pharmacol. 2016 Aug 8;7:245. doi: 10.3389/fphar.2016.00245. eCollection 2016.


Overexpression of β-Catenin Induces Cisplatin Resistance in Oral Squamous Cell Carcinoma.

Li L, Liu HC, Wang C, Liu X, Hu FC, Xie N, Lü L, Chen X, Huang HZ.

Biomed Res Int. 2016;2016:5378567. doi: 10.1155/2016/5378567. Epub 2016 Jul 27.


Mitochondria, cholesterol and cancer cell metabolism.

Ribas V, García-Ruiz C, Fernández-Checa JC.

Clin Transl Med. 2016 Dec;5(1):22. doi: 10.1186/s40169-016-0106-5. Epub 2016 Jul 25. Review.


Arctigenin Treatment Protects against Brain Damage through an Anti-Inflammatory and Anti-Apoptotic Mechanism after Needle Insertion.

Song J, Li N, Xia Y, Gao Z, Zou SF, Kong L, Yao YJ, Jiao YN, Yan YH, Li SH, Tao ZY, Lian G, Yang JX, Kang TG.

Front Pharmacol. 2016 Jun 22;7:182. doi: 10.3389/fphar.2016.00182. eCollection 2016.


An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway.

Garner TP, Reyna DE, Priyadarshi A, Chen HC, Li S, Wu Y, Ganesan YT, Malashkevich VN, Almo SS, Cheng EH, Gavathiotis E.

Mol Cell. 2016 Aug 4;63(3):485-97. doi: 10.1016/j.molcel.2016.06.010. Epub 2016 Jul 14.


In vitro and in vivo study of epigallocatechin-3-gallate-induced apoptosis in aerobic glycolytic hepatocellular carcinoma cells involving inhibition of phosphofructokinase activity.

Li S, Wu L, Feng J, Li J, Liu T, Zhang R, Xu S, Cheng K, Zhou Y, Zhou S, Kong R, Chen K, Wang F, Xia Y, Lu J, Zhou Y, Dai W, Guo C.

Sci Rep. 2016 Jun 28;6:28479. doi: 10.1038/srep28479.


The Human Bcl-2 Family Member Bcl-rambo Localizes to Mitochondria and Induces Apoptosis and Morphological Aberrations in Drosophila.

Nakazawa M, Matsubara H, Matsushita Y, Watanabe M, Vo N, Yoshida H, Yamaguchi M, Kataoka T.

PLoS One. 2016 Jun 27;11(6):e0157823. doi: 10.1371/journal.pone.0157823. eCollection 2016.


Propofol Decreases Endoplasmic Reticulum Stress-Mediated Apoptosis in Retinal Pigment Epithelial Cells.

Zhou X, Wei Y, Qiu S, Xu Y, Zhang T, Zhang S.

PLoS One. 2016 Jun 16;11(6):e0157590. doi: 10.1371/journal.pone.0157590. eCollection 2016.


Induction of Apoptosis by the Nonstructural Protein 4 and 10 of Porcine Reproductive and Respiratory Syndrome Virus.

Yuan S, Zhang N, Xu L, Zhou L, Ge X, Guo X, Yang H.

PLoS One. 2016 Jun 16;11(6):e0156518. doi: 10.1371/journal.pone.0156518. eCollection 2016.


Acute Sensitivity of Ph-like Acute Lymphoblastic Leukemia to the SMAC-Mimetic Birinapant.

Richmond J, Robbins A, Evans K, Beck D, Kurmasheva RT, Billups CA, Carol H, Heatley S, Sutton R, Marshall GM, White D, Pimanda J, Houghton PJ, Smith MA, Lock RB.

Cancer Res. 2016 Aug 1;76(15):4579-91. doi: 10.1158/0008-5472.CAN-16-0523. Epub 2016 Jun 14.


Donepezil delays photoreceptor apoptosis induced by N-methyl-N-nitrosourea in mice.

Wu L, Xu M, Liu S, Chen G, Zhang F, Zhao Y, Yi J.

Exp Ther Med. 2016 Jun;11(6):2446-2454. Epub 2016 Apr 11.

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