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Results: 1 to 20 of 23

1.

Mesothelin-targeted immunotherapies for malignant pleural mesothelioma.

Villena-Vargas J, Adusumilli PS.

Ann Cardiothorac Surg. 2012 Nov;1(4):466-71. doi: 10.3978/j.issn.2225-319X.2012.10.03. No abstract available.

PMID:
23977538
[PubMed]
Free PMC Article
2.

Targeting CD133 in an in vivo ovarian cancer model reduces ovarian cancer progression.

Skubitz AP, Taras EP, Boylan KL, Waldron NN, Oh S, Panoskaltsis-Mortari A, Vallera DA.

Gynecol Oncol. 2013 Sep;130(3):579-87. doi: 10.1016/j.ygyno.2013.05.027. Epub 2013 May 27.

PMID:
23721800
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas.

Mossman BT, Shukla A, Heintz NH, Verschraegen CF, Thomas A, Hassan R.

Am J Pathol. 2013 Apr;182(4):1065-77. doi: 10.1016/j.ajpath.2012.12.028. Epub 2013 Feb 8. Review.

PMID:
23395095
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Tumor therapy with a urokinase plasminogen activator-activated anthrax lethal toxin alone and in combination with paclitaxel.

Wein AN, Liu S, Zhang Y, McKenzie AT, Leppla SH.

Invest New Drugs. 2013 Feb;31(1):206-12. doi: 10.1007/s10637-012-9847-1. Epub 2012 Jul 28.

PMID:
22843210
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Bispecific targeting of EGFR and uPAR in a mouse model of head and neck squamous cell carcinoma.

Waldron NN, Oh S, Vallera DA.

Oral Oncol. 2012 Dec;48(12):1202-7. doi: 10.1016/j.oraloncology.2012.06.002. Epub 2012 Jul 20.

PMID:
22818892
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A multifunctional mesothelin antibody-tagged microparticle targets human mesotheliomas.

Macura SL, Hillegass JM, Steinbacher JL, MacPherson MB, Shukla A, Beuschel SL, Perkins TN, Butnor KJ, Lathrop MJ, Sayan M, Hekmatyar K, Taatjes DJ, Kauppinen RA, Landry CC, Mossman BT.

J Histochem Cytochem. 2012 Sep;60(9):658-74. doi: 10.1369/0022155412452567. Epub 2012 Jun 21.

PMID:
22723527
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Luminal membrane expression of mesothelin is a prominent poor prognostic factor for gastric cancer.

Einama T, Homma S, Kamachi H, Kawamata F, Takahashi K, Takahashi N, Taniguchi M, Kamiyama T, Furukawa H, Matsuno Y, Tanaka S, Nishihara H, Taketomi A, Todo S.

Br J Cancer. 2012 Jun 26;107(1):137-42. doi: 10.1038/bjc.2012.235. Epub 2012 May 29.

PMID:
22644300
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mesothelin-targeted agents in clinical trials and in preclinical development.

Kelly RJ, Sharon E, Pastan I, Hassan R.

Mol Cancer Ther. 2012 Mar;11(3):517-25. doi: 10.1158/1535-7163.MCT-11-0454. Epub 2012 Feb 17. Review.

PMID:
22351743
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Synergistic antitumor activity of anti-CD25 recombinant immunotoxin LMB-2 with chemotherapy.

Singh R, Zhang Y, Pastan I, Kreitman RJ.

Clin Cancer Res. 2012 Jan 1;18(1):152-60. doi: 10.1158/1078-0432.CCR-11-1839. Epub 2011 Nov 8.

PMID:
22068660
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Advances in liver cancer antibody therapies: a focus on glypican-3 and mesothelin.

Ho M.

BioDrugs. 2011 Oct 1;25(5):275-84. doi: 10.2165/11595360-000000000-00000. Review.

PMID:
21942912
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Targeting tumor-initiating cancer cells with dCD133KDEL shows impressive tumor reductions in a xenotransplant model of human head and neck cancer.

Waldron NN, Kaufman DS, Oh S, Inde Z, Hexum MK, Ohlfest JR, Vallera DA.

Mol Cancer Ther. 2011 Oct;10(10):1829-38. doi: 10.1158/1535-7163.MCT-11-0206. Epub 2011 Aug 23.

PMID:
21862685
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Molecular targeted approaches for treatment of pancreatic cancer.

Huang ZQ, Saluja AK, Dudeja V, Vickers SM, Buchsbaum DJ.

Curr Pharm Des. 2011;17(21):2221-38. Review.

PMID:
21777178
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Cytotoxic activity of immunotoxin SS1P is modulated by TACE-dependent mesothelin shedding.

Zhang Y, Chertov O, Zhang J, Hassan R, Pastan I.

Cancer Res. 2011 Sep 1;71(17):5915-22. doi: 10.1158/0008-5472.CAN-11-0466. Epub 2011 Jul 20.

PMID:
21775520
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor.

Moon EK, Carpenito C, Sun J, Wang LC, Kapoor V, Predina J, Powell DJ Jr, Riley JL, June CH, Albelda SM.

Clin Cancer Res. 2011 Jul 15;17(14):4719-30. doi: 10.1158/1078-0432.CCR-11-0351. Epub 2011 May 24.

PMID:
21610146
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A guide to taming a toxin--recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer.

Weldon JE, Pastan I.

FEBS J. 2011 Dec;278(23):4683-700. doi: 10.1111/j.1742-4658.2011.08182.x. Epub 2011 Jun 2. Review.

PMID:
21585657
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Pentostatin plus cyclophosphamide safely and effectively prevents immunotoxin immunogenicity in murine hosts.

Mossoba ME, Onda M, Taylor J, Massey PR, Treadwell S, Sharon E, Hassan R, Pastan I, Fowler DH.

Clin Cancer Res. 2011 Jun 1;17(11):3697-705. doi: 10.1158/1078-0432.CCR-11-0493. Epub 2011 Apr 26.

PMID:
21521777
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

In vivo imaging of human malignant mesothelioma grown orthotopically in the peritoneal cavity of nude mice.

Feng M, Zhang J, Anver M, Hassan R, Ho M.

J Cancer. 2011 Mar 1;2:123-31.

PMID:
21479131
[PubMed]
Free PMC Article
18.

The development and characterization of a human mesothelioma in vitro 3D model to investigate immunotoxin therapy.

Xiang X, Phung Y, Feng M, Nagashima K, Zhang J, Broaddus VC, Hassan R, Fitzgerald D, Ho M.

PLoS One. 2011 Jan 31;6(1):e14640. doi: 10.1371/journal.pone.0014640.

PMID:
21305058
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The detection, treatment, and biology of epithelial ovarian cancer.

Gubbels JA, Claussen N, Kapur AK, Connor JP, Patankar MS.

J Ovarian Res. 2010 Mar 29;3:8. doi: 10.1186/1757-2215-3-8.

PMID:
20350313
[PubMed]
Free PMC Article
20.

Monoclonal antibodies in the treatment of pancreatic cancer.

Huang ZQ, Buchsbaum DJ.

Immunotherapy. 2009 Mar;1(2):223-9. doi: 10.2217/1750743X.1.2.223. Review.

PMID:
20046965
[PubMed - indexed for MEDLINE]
Free PMC Article

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