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Results: 16

1.

Quinacrine Inhibits Cell Growth and Induces Apoptosis in Human Gastric Cancer Cell Line SGC-7901.

Wu X, Wang Y, Wang H, Wang Q, Wang L, Miao J, Cui F, Wang J.

Curr Ther Res Clin Exp. 2012 Feb;73(1-2):52-64. doi: 10.1016/j.curtheres.2012.02.003.

PMID:
24653512
[PubMed]
Free PMC Article
2.

Unraveling regulatory programs for NF-kappaB, p53 and microRNAs in head and neck squamous cell carcinoma.

Yan B, Li H, Yang X, Shao J, Jang M, Guan D, Zou S, Van Waes C, Chen Z, Zhan M.

PLoS One. 2013 Sep 19;8(9):e73656. doi: 10.1371/journal.pone.0073656. eCollection 2013.

PMID:
24069219
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

HSP90 Inhibitor SNX5422/2112 Targets the Dysregulated Signal and Transcription Factor Network and Malignant Phenotype of Head and Neck Squamous Cell Carcinoma.

Friedman JA, Wise SC, Hu M, Gouveia C, Vander Broek R, Freudlsperger C, Kannabiran VR, Arun P, Mitchell JB, Chen Z, Van Waes C.

Transl Oncol. 2013 Aug 1;6(4):429-41. Print 2013 Aug.

PMID:
23908686
[PubMed]
Free PMC Article
4.

PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer.

Herzog A, Bian Y, Vander Broek R, Hall B, Coupar J, Cheng H, Sowers AL, Cook JD, Mitchell JB, Chen Z, Kulkarni AB, Van Waes C.

Clin Cancer Res. 2013 Jul 15;19(14):3808-19. doi: 10.1158/1078-0432.CCR-12-2716. Epub 2013 May 2.

PMID:
23640975
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Quinacrine impairs enterovirus 71 RNA replication by preventing binding of polypyrimidine-tract binding protein with internal ribosome entry sites.

Wang J, Du J, Wu Z, Jin Q.

PLoS One. 2013;8(1):e52954. doi: 10.1371/journal.pone.0052954. Epub 2013 Jan 3.

PMID:
23301007
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers.

Freudlsperger C, Bian Y, Contag Wise S, Burnett J, Coupar J, Yang X, Chen Z, Van Waes C.

Oncogene. 2013 Mar 21;32(12):1549-59. doi: 10.1038/onc.2012.171. Epub 2012 May 28.

PMID:
22641218
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

TNF-α promotes c-REL/ΔNp63α interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer.

Lu H, Yang X, Duggal P, Allen CT, Yan B, Cohen J, Nottingham L, Romano RA, Sinha S, King KE, Weinberg WC, Chen Z, Van Waes C.

Cancer Res. 2011 Nov 1;71(21):6867-77. doi: 10.1158/0008-5472.CAN-11-2460. Epub 2011 Sep 20.

PMID:
21933882
[PubMed - indexed for MEDLINE]
Free PMC Article
8.
9.

YAP dysregulation by phosphorylation or ΔNp63-mediated gene repression promotes proliferation, survival and migration in head and neck cancer subsets.

Ehsanian R, Brown M, Lu H, Yang XP, Pattatheyil A, Yan B, Duggal P, Chuang R, Doondeea J, Feller S, Sudol M, Chen Z, Van Waes C.

Oncogene. 2010 Nov 18;29(46):6160-71. doi: 10.1038/onc.2010.339. Epub 2010 Aug 23.

PMID:
20729916
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Emergence of protein kinase CK2 as a key target in cancer therapy.

Trembley JH, Chen Z, Unger G, Slaton J, Kren BT, Van Waes C, Ahmed K.

Biofactors. 2010 May-Jun;36(3):187-95. doi: 10.1002/biof.96. Review.

PMID:
20533398
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

CK2 modulation of NF-kappaB, TP53, and the malignant phenotype in head and neck cancer by anti-CK2 oligonucleotides in vitro or in vivo via sub-50-nm nanocapsules.

Brown MS, Diallo OT, Hu M, Ehsanian R, Yang X, Arun P, Lu H, Korman V, Unger G, Ahmed K, Van Waes C, Chen Z.

Clin Cancer Res. 2010 Apr 15;16(8):2295-307. doi: 10.1158/1078-0432.CCR-09-3200. Epub 2010 Apr 6.

PMID:
20371694
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Current and potential inflammation targeted therapies in head and neck cancer.

Wang F, Arun P, Friedman J, Chen Z, Van Waes C.

Curr Opin Pharmacol. 2009 Aug;9(4):389-95. doi: 10.1016/j.coph.2009.06.005. Epub 2009 Jun 29. Review.

PMID:
19570715
[PubMed - indexed for MEDLINE]
Free PMC Article
13.
14.

Attenuated transforming growth factor beta signaling promotes nuclear factor-kappaB activation in head and neck cancer.

Cohen J, Chen Z, Lu SL, Yang XP, Arun P, Ehsanian R, Brown MS, Lu H, Yan B, Diallo O, Wang XJ, Van Waes C.

Cancer Res. 2009 Apr 15;69(8):3415-24. doi: 10.1158/0008-5472.CAN-08-3704. Epub 2009 Apr 7.

PMID:
19351843
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Molecular techniques and genetic alterations in head and neck cancer.

Ha PK, Chang SS, Glazer CA, Califano JA, Sidransky D.

Oral Oncol. 2009 Apr-May;45(4-5):335-9. doi: 10.1016/j.oraloncology.2008.05.015. Epub 2008 Jul 31. Review.

PMID:
18674960
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Systems biology-defined NF-kappaB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status.

Yan B, Chen G, Saigal K, Yang X, Jensen ST, Van Waes C, Stoeckert CJ, Chen Z.

Genome Biol. 2008;9(3):R53. doi: 10.1186/gb-2008-9-3-r53. Epub 2008 Mar 11.

PMID:
18334025
[PubMed - indexed for MEDLINE]
Free PMC Article

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