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Cited In for PubMed (Select 18006685)


Dynamic loading and redistribution of the Mcm2-7 helicase complex through the cell cycle.

Powell SK, MacAlpine HK, Prinz JA, Li Y, Belsky JA, MacAlpine DM.

EMBO J. 2015 Feb 12;34(4):531-43. doi: 10.15252/embj.201488307. Epub 2015 Jan 2.


Functional insight into the role of Orc6 in septin complex filament formation in Drosophila.

Akhmetova K, Balasov M, Huijbregts RP, Chesnokov I.

Mol Biol Cell. 2015 Jan 1;26(1):15-28. doi: 10.1091/mbc.E14-02-0734. Epub 2014 Oct 29.


DNA damage enhanced by the attenuation of SLD5 delays cell cycle restoration in normal cells but not in cancer cells.

Gong ZY, Kidoya H, Mohri T, Han Y, Takakura N.

PLoS One. 2014 Oct 21;9(10):e110483. doi: 10.1371/journal.pone.0110483. eCollection 2014.


Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and function.

Sun J, Fernandez-Cid A, Riera A, Tognetti S, Yuan Z, Stillman B, Speck C, Li H.

Genes Dev. 2014 Oct 15;28(20):2291-303. doi: 10.1101/gad.242313.114.


Origin plasticity during budding yeast DNA replication in vitro.

Gros J, Devbhandari S, Remus D.

EMBO J. 2014 Mar 18;33(6):621-36. doi: 10.1002/embj.201387278. Epub 2014 Feb 24.


The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation.

Evrin C, Fernández-Cid A, Riera A, Zech J, Clarke P, Herrera MC, Tognetti S, Lurz R, Speck C.

Nucleic Acids Res. 2014 Feb;42(4):2257-69. doi: 10.1093/nar/gkt1148. Epub 2013 Nov 14.


A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation.

Bleichert F, Balasov M, Chesnokov I, Nogales E, Botchan MR, Berger JM.

Elife. 2013 Oct 8;2:e00882. doi: 10.7554/eLife.00882.


Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.

Sun J, Evrin C, Samel SA, Fernández-Cid A, Riera A, Kawakami H, Stillman B, Speck C, Li H.

Nat Struct Mol Biol. 2013 Aug;20(8):944-51. doi: 10.1038/nsmb.2629. Epub 2013 Jul 14.


Activation of a human chromosomal replication origin by protein tethering.

Chen X, Liu G, Leffak M.

Nucleic Acids Res. 2013 Jul;41(13):6460-74. doi: 10.1093/nar/gkt368. Epub 2013 May 8.


Flipping the switch from g1 to s phase with e3 ubiquitin ligases.

Rizzardi LF, Cook JG.

Genes Cancer. 2012 Nov;3(11-12):634-48. doi: 10.1177/1947601912473307.


Helicase loading at chromosomal origins of replication.

Bell SP, Kaguni JM.

Cold Spring Harb Perspect Biol. 2013 Jun 1;5(6). pii: a010124. doi: 10.1101/cshperspect.a010124. Review.


Dbf4: the whole is greater than the sum of its parts.

Matthews LA, Guarné A.

Cell Cycle. 2013 Apr 15;12(8):1180-8. doi: 10.4161/cc.24416. Epub 2013 Apr 2. Review.


Dbf4 and Cdc7 proteins promote DNA replication through interactions with distinct Mcm2-7 protein subunits.

Ramer MD, Suman ES, Richter H, Stanger K, Spranger M, Bieberstein N, Duncker BP.

J Biol Chem. 2013 May 24;288(21):14926-35. doi: 10.1074/jbc.M112.392910. Epub 2013 Apr 2.


Loading and activation of DNA replicative helicases: the key step of initiation of DNA replication.

Li Y, Araki H.

Genes Cells. 2013 Apr;18(4):266-77. doi: 10.1111/gtc.12040. Epub 2013 Mar 5. Review.


In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.

Evrin C, Fernández-Cid A, Zech J, Herrera MC, Riera A, Clarke P, Brill S, Lurz R, Speck C.

Nucleic Acids Res. 2013 Mar 1;41(5):3162-72. doi: 10.1093/nar/gkt043. Epub 2013 Feb 1.


Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology.

Slaymaker IM, Fu Y, Toso DB, Ranatunga N, Brewster A, Forsburg SL, Zhou ZH, Chen XS.

Nucleic Acids Res. 2013 Mar 1;41(5):3446-56. doi: 10.1093/nar/gkt022. Epub 2013 Jan 29.


The origin recognition complex: a biochemical and structural view.

Li H, Stillman B.

Subcell Biochem. 2012;62:37-58. doi: 10.1007/978-94-007-4572-8_3. Review.


A quantitative model of the initiation of DNA replication in Saccharomyces cerevisiae predicts the effects of system perturbations.

Gidvani RD, Sudmant P, Li G, DaSilva LF, McConkey BJ, Duncker BP, Ingalls BP.

BMC Syst Biol. 2012 Jun 27;6:78. doi: 10.1186/1752-0509-6-78.


Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment.

Varma D, Chandrasekaran S, Sundin LJ, Reidy KT, Wan X, Chasse DA, Nevis KR, DeLuca JG, Salmon ED, Cook JG.

Nat Cell Biol. 2012 May 13;14(6):593-603. doi: 10.1038/ncb2489.


Identification of ORC1/CDC6-interacting factors in Trypanosoma brucei reveals critical features of origin recognition complex architecture.

Tiengwe C, Marcello L, Farr H, Gadelha C, Burchmore R, Barry JD, Bell SD, McCulloch R.

PLoS One. 2012;7(3):e32674. doi: 10.1371/journal.pone.0032674. Epub 2012 Mar 8.

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