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Items: 1 to 20 of 28


Deletion of GSTA4-4 results in increased mitochondrial post-translational modification of proteins by reactive aldehydes following chronic ethanol consumption in mice.

Shearn CT, Fritz KS, Shearn AH, Saba LM, Mercer KE, Engi B, Galligan JJ, Zimniak P, Orlicky DJ, Ronis MJ, Petersen DR.

Redox Biol. 2016 Apr;7:68-77. doi: 10.1016/j.redox.2015.11.013. Epub 2015 Nov 27.


Increased hepatocellular protein carbonylation in human end-stage alcoholic cirrhosis.

Shearn CT, Orlicky DJ, Saba LM, Shearn AH, Petersen DR.

Free Radic Biol Med. 2015 Dec;89:1144-53. doi: 10.1016/j.freeradbiomed.2015.10.420. Epub 2015 Oct 27.


Herbal SGR Formula Prevents Acute Ethanol-Induced Liver Steatosis via Inhibition of Lipogenesis and Enhancement Fatty Acid Oxidation in Mice.

Qiu P, Li X, Kong DS, Li HZ, Niu CC, Pan SH.

Evid Based Complement Alternat Med. 2015;2015:613584. doi: 10.1155/2015/613584. Epub 2015 May 25.


Liver steatosis in hepatitis C patients.

González-Reimers E, Quintero-Platt G, Rodríguez-Gaspar M, Alemán-Valls R, Pérez-Hernández O, Santolaria-Fernández F.

World J Hepatol. 2015 Jun 8;7(10):1337-46. doi: 10.4254/wjh.v7.i10.1337. Review.


Pathogenesis of alcoholic liver disease: role of oxidative metabolism.

Ceni E, Mello T, Galli A.

World J Gastroenterol. 2014 Dec 21;20(47):17756-72. doi: 10.3748/wjg.v20.i47.17756. Review.


Ethanol and liver: recent insights into the mechanisms of ethanol-induced fatty liver.

Liu J.

World J Gastroenterol. 2014 Oct 28;20(40):14672-85. doi: 10.3748/wjg.v20.i40.14672. Review.


Chronic alcohol ingestion in rats alters lung metabolism, promotes lipid accumulation, and impairs alveolar macrophage functions.

Romero F, Shah D, Duong M, Stafstrom W, Hoek JB, Kallen CB, Lang CH, Summer R.

Am J Respir Cell Mol Biol. 2014 Dec;51(6):840-9. doi: 10.1165/rcmb.2014-0127OC.


Steatosis and steatohepatitis: complex disorders.

Bettermann K, Hohensee T, Haybaeck J.

Int J Mol Sci. 2014 Jun 3;15(6):9924-44. doi: 10.3390/ijms15069924. Review.


Pharmacological ceramide reduction alleviates alcohol-induced steatosis and hepatomegaly in adiponectin knockout mice.

Correnti JM, Juskeviciute E, Swarup A, Hoek JB.

Am J Physiol Gastrointest Liver Physiol. 2014 Jun 1;306(11):G959-73. doi: 10.1152/ajpgi.00395.2013. Epub 2014 Apr 17.


Identification of 5' AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol.

Shearn CT, Backos DS, Orlicky DJ, Smathers-McCullough RL, Petersen DR.

J Biol Chem. 2014 May 30;289(22):15449-62. doi: 10.1074/jbc.M113.543942. Epub 2014 Apr 10.


5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo.

Hasenour CM, Ridley DE, Hughey CC, James FD, Donahue EP, Shearer J, Viollet B, Foretz M, Wasserman DH.

J Biol Chem. 2014 Feb 28;289(9):5950-9. doi: 10.1074/jbc.M113.528232. Epub 2014 Jan 8.


Zidovudine (AZT) and hepatic lipid accumulation: implication of inflammation, oxidative and endoplasmic reticulum stress mediators.

Banerjee A, Abdelmegeed MA, Jang S, Song BJ.

PLoS One. 2013 Oct 11;8(10):e76850. doi: 10.1371/journal.pone.0076850. eCollection 2013.


Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis.

Shearn CT, Smathers RL, Jiang H, Orlicky DJ, Maclean KN, Petersen DR.

J Nutr Biochem. 2013 Aug;24(8):1436-45. doi: 10.1016/j.jnutbio.2012.12.002. Epub 2013 Mar 1.


The hepatic cannabinoid 1 receptor as a modulator of hepatic energy state and food intake.

Cooper ME, Regnell SE.

Br J Clin Pharmacol. 2014 Jan;77(1):21-30. doi: 10.1111/bcp.12102. Review.


Mechanisms mediating the effects of alcohol and HIV anti-retroviral agents on mTORC1, mTORC2 and protein synthesis in myocytes.

Hong-Brown LQ, Kazi AA, Lang CH.

World J Biol Chem. 2012 Jun 26;3(6):110-20. doi: 10.4331/wjbc.v3.i6.110.


Toward a unifying hypothesis of metabolic syndrome.

Bremer AA, Mietus-Snyder M, Lustig RH.

Pediatrics. 2012 Mar;129(3):557-70. doi: 10.1542/peds.2011-2912. Epub 2012 Feb 20. Review.


The effect of alcohol on postprandial and fasting triglycerides.

Van de Wiel A.

Int J Vasc Med. 2012;2012:862504. doi: 10.1155/2012/862504. Epub 2011 Sep 22.


Alteration of hepatic nuclear receptor-mediated signaling pathways in hepatitis C virus patients with and without a history of alcohol drinking.

Wu C, Gilroy R, Taylor R, Olyaee M, Abdulkarim B, Forster J, O'Neil M, Damjanov I, Wan YJ.

Hepatology. 2011 Dec;54(6):1966-74. doi: 10.1002/hep.24645.


Activated AMPK inhibits PPAR-{alpha} and PPAR-{gamma} transcriptional activity in hepatoma cells.

Sozio MS, Lu C, Zeng Y, Liangpunsakul S, Crabb DW.

Am J Physiol Gastrointest Liver Physiol. 2011 Oct;301(4):G739-47. doi: 10.1152/ajpgi.00161.2011. Epub 2011 Jun 23.


Mitochondria and redox signaling in steatohepatitis.

Morris EM, Rector RS, Thyfault JP, Ibdah JA.

Antioxid Redox Signal. 2011 Jul 15;15(2):485-504. doi: 10.1089/ars.2010.3795. Epub 2011 Apr 26. Review.

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