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Items: 8

1.

Moving on from GWAS: functional studies on the G6PC2 gene implicated in the regulation of fasting blood glucose.

O'Brien RM.

Curr Diab Rep. 2013 Dec;13(6):768-77. doi: 10.1007/s11892-013-0422-8.

2.

Characterization of the human SLC30A8 promoter and intronic enhancer.

Pound LD, Sarkar SA, Cauchi S, Wang Y, Oeser JK, Lee CE, Froguel P, Hutton JC, O'Brien RM.

J Mol Endocrinol. 2011 Sep 30;47(3):251-9. doi: 10.1530/JME-11-0055. Print 2011 Dec.

3.

The pancreatic islet β-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer.

Pound LD, Hang Y, Sarkar SA, Wang Y, Milam LA, Oeser JK, Printz RL, Lee CE, Stein R, Hutton JC, O'Brien RM.

Biochem J. 2011 Jan 1;433(1):95-105. doi: 10.1042/BJ20101488.

4.

Common polymorphisms in MTNR1B, G6PC2 and GCK are associated with increased fasting plasma glucose and impaired beta-cell function in Chinese subjects.

Tam CH, Ho JS, Wang Y, Lee HM, Lam VK, Germer S, Martin M, So WY, Ma RC, Chan JC, Ng MC.

PLoS One. 2010 Jul 8;5(7):e11428. doi: 10.1371/journal.pone.0011428.

5.

Genetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels.

Bouatia-Naji N, Bonnefond A, Baerenwald DA, Marchand M, Bugliani M, Marchetti P, Pattou F, Printz RL, Flemming BP, Umunakwe OC, Conley NL, Vaxillaire M, Lantieri O, Balkau B, Marre M, Lévy-Marchal C, Elliott P, Jarvelin MR, Meyre D, Dina C, Oeser JK, Froguel P, O'Brien RM.

Diabetes. 2010 Oct;59(10):2662-71. doi: 10.2337/db10-0389. Epub 2010 Jul 9.

6.

A retrospective review of the roles of multifunctional glucose-6-phosphatase in blood glucose homeostasis: Genesis of the tuning/retuning hypothesis.

Nordlie RC, Foster JD.

Life Sci. 2010 Sep 11;87(11-12):339-49. doi: 10.1016/j.lfs.2010.06.021. Epub 2010 Jul 21. Review.

7.

Glucose-6-phosphatase catalytic subunit gene family.

Hutton JC, O'Brien RM.

J Biol Chem. 2009 Oct 23;284(43):29241-5. doi: 10.1074/jbc.R109.025544. Epub 2009 Aug 20. Review.

8.

Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression.

Martin CC, Flemming BP, Wang Y, Oeser JK, O'Brien RM.

J Mol Endocrinol. 2008 Nov;41(5):315-28. doi: 10.1677/JME-08-0062. Epub 2008 Aug 27.

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